Condition

Metastatic Malignant Neoplasm in the Leptomeninges

ClinicalTrials.gov condition label

Clinical trials6

Recruiting4

Common interventions22

Lead sponsors shown5

Clinical trials

6 shown

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung CancerNCT06910761 · 2025-05-05

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM TrialNCT06500481 · 2025-03-04

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung CancerNCT06518057 · 2025-03-03

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung CancerNCT05746325 · 2023-04-07

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal MetastasisNCT06137651 · 2023-12-31

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal MetastasesNCT03696030 · 2018-11-27

ACTIVE_NOT_RECRUITING

Common interventions

Leading sponsors

City of Hope Medical Center2 Mayo Clinic1 Northwestern University1 NRG Oncology1 University of Washington1

Trial status mix

RECRUITING4

ACTIVE_NOT_RECRUITING1

WITHDRAWN1

Phase mix

PHASE12

PHASE22

NA1

PHASE31

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.