Condition

Depression, Unipolar

ClinicalTrials.gov condition label

Clinical trials48

Recruiting9

Common interventions25

Lead sponsors shown15

Clinical trials

48 shown

Maternal Mindfulness: Depression and Postpartum PainNCT05400382 · 2025-12-01

Adjunctive Bright Light Therapy in Adolescents With Depression and EveningnessNCT06973759 · 2025-11-01

Natural History of Depression, Bipolar Disorder and Suicide RiskNCT06462196 · 2024-09-09

The Cerebral and Cognitive Changes After Intermittent Theta Burst Stimulation (iTBS) Treatment for DepressionNCT06534684 · 2024-02-12

BioClock: Bright Light Therapy for Depressive DisordersNCT05958940 · 2024-02-08

Intermittent Theta-burst Stimulation for Major Depression: an Intensity-response StudyNCT06392867 · 2024-01-08

Effects of CBT and BLT in Youth With Unipolar Depression and Evening ChronotypeNCT06092411 · 2023-10-31

FMRI-neurofeedback in DepressionNCT05640089 · 2023-01-25

Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With DepressionNCT05011864 · 2021-11-01

Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled TrialNCT07051148 · 2027-05-01

NOT_YET_RECRUITING

Development and Evaluation of a Digital Aftercare Program for Adolescents (12-17 Years) With Depressive Symptoms After Hospital Discharge (Mind-WIN Pilot Study) (Mind-WIN Pilot)NCT07007247 · 2025-05-13

ENROLLING_BY_INVITATION

Repeated Neurocognitive Measurements in Depressed PatientsNCT05991232 · 2025-05-01

Psychotherapy Feasibility Pilot of the Carolina Recovery From Depression ProtocolNCT06590038 · 2025-03-03

Pilot Study: Investigating Mood Changes After Slow-wave EnhancementNCT05146427 · 2025-01-01

CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among LatinosNCT06139159 · 2023-11-10

ACTIVE_NOT_RECRUITING

Safety, Tolerability and Antidepressant Effects of DMT in Patients With DepressionNCT06094907 · 2023-10-09

Lifestyle InterVEntion Study in General Practice: LIVES - GPNCT06286345 · 2023-08-01

Psychiatric Orders in Psychoanalytic Treatment of ASDNCT05930912 · 2023-06-01

Ketamine + Mindfulness for DepressionNCT05168735 · 2022-02-01

Acceptability and Feasibility of an 8-week Online Mindfulness-Based Cognitive Therapy Program Among Undergraduate StudentsNCT05114824 · 2021-09-23

Repeated Neurocognitive Measurements in Depressed PatientsNCT04916548 · 2021-09-16

IM Ketamine vs Midazolam for Suicidal ER PatientsNCT04640636 · 2021-02-09

LIVES: Personalized Lifestyle Intervention for Patients With DepressionNCT05767073 · 2020-09-01

SMART-DAPPER: Leveraging the Depression And Primary-care Partnership for Effectiveness-implementation Research ProjectNCT03466346 · 2020-08-31

The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT)NCT04399070 · 2020-08-01

Validity and Reliability of Vietnamese Version of 17items-Hamilton Depression Rating ScaleNCT04205747 · 2020-01-01

Pramipexole to Target "Anhedonic Depression"NCT04121091 · 2019-10-04

Whole-body Hyperthermia for Moderate to Severe Depressive DisorderNCT03906149 · 2019-07-01

Whole-body Hyperthermia for Mild to Moderate Depressive DisorderNCT03906175 · 2019-06-11

Tracking Depression Symptoms With a Health ChatbotNCT03990389 · 2019-02-20

Psychotherapeutic Augmentation of Brain Stimulation EffectsNCT04159285 · 2019-01-05

Machine Learning to Predict Clinical Response to TMSNCT03847688 · 2018-10-22

A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on DepressionNCT03623711 · 2018-08-01

PF-04995274 and Emotional Processing in Treatment Resistant DepressionNCT03515733 · 2018-05-31

PF-04995274 and Emotional Processing in Un-medicated DepressionNCT03516604 · 2018-05-16

Combinatorial Pharmacogenomics Testing in Treatment-Naïve Major Depressive DisorderNCT03537547 · 2018-05-04

Chronobiology and Depression: Circadian Analytics as a Biomarker for Depressive SubtypesNCT03538275 · 2018-03-13

Sleep, Wake and Light Therapy for DepressionNCT03405493 · 2018-01-18

Reaching and Engaging Depressed Senior Center Clients (REDS)NCT03246789 · 2018-01-01

Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of VortioxetineNCT02969876 · 2017-08-24

Novel Neural Circuit Biomarkers of Major Depression Response to CCBTNCT03096886 · 2017-06-05

Trans-diagnostic Group CBT vs. Standard Group CBT for Depression, Social Anxiety and Agoraphobia/Panic DisorderNCT02954731 · 2016-12-01

Gaze Contingent Feedback in Major Depressive Disorder (MDD)NCT02945735 · 2016-11-06

Pulsed Electro Magnetic Fields (PEMF) in DepressionNCT03556735 · 2016-09-01

Exercise for DepressionNCT02874833 · 2016-07-01

Neural Mechanisms Underlying the Antidepressant Effects of Sleep DeprivationNCT03169543 · 2016-04-01

Low-Dose Naltrexone (LDN) for Depression Relapse and RecurrenceNCT01874951 · 2013-06-01

Treating Major Depression With Yoga: A Prospective, Randomized Controlled Pilot TrialNCT01210651 · 2010-05-01

Common interventions

Leading sponsors

University of Pennsylvania3 Massachusetts General Hospital2 Rebecca Price2 Universität Duisburg-Essen2 University Medical Center Groningen2 University of California, San Francisco2 University of Oxford2 Brown University1 Charite University, Berlin, Germany1 Chinese University of Hong Kong1 Drexel University1 Jay Fournier1 Johannes Gutenberg University Mainz1 King's College London1 Maastricht University Medical Center1

Trial status mix

COMPLETED23

RECRUITING9

UNKNOWN8

TERMINATED2

WITHDRAWN2

ACTIVE_NOT_RECRUITING1

ENROLLING_BY_INVITATION1

NOT_YET_RECRUITING1

SUSPENDED1

Phase mix

NA31

PHASE26

PHASE15

PHASE43

EARLY_PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.