Condition

Heart Failure NYHA Class IV

ClinicalTrials.gov condition label

Clinical trials31

Recruiting5

Common interventions25

Lead sponsors shown15

Clinical trials

31 shown

Sustaining Home Heart Failure Palliative Care in Rural AppalachiaNCT06791850 · 2025-04-01

Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac SurgeryNCT05632432 · 2024-04-01

Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart DiseaseNCT05647213 · 2023-02-03

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health SystemNCT04237701 · 2019-10-01

Study of the Clinical Impact of Surgical Correction of Tricuspid Insufficiency in Implantable LVAD PatientsNCT02537769 · 2015-08-01

Narrative Intervention for Chronic Illness- Heart Failure Trial (NICI-HF)NCT06097481 · 2025-09-01

NOT_YET_RECRUITING

REDUCED FUNCTIONALITY AND KINESIOPHOBIA IN PATIENTS WITH HEART FAILURE: USE OF ALTERNATIVE THERAPEUTIC STRATEGIESNCT07099495 · 2025-08-18

NOT_YET_RECRUITING

Association Between the Sit-To-Stand Test and the Prognosis of Patients With Heart FailureNCT07045649 · 2025-07-16

ACTIVE_NOT_RECRUITING

Whole Heart Radiotherapy for End-stage Heart FailureNCT06299176 · 2025-04-30

ENROLLING_BY_INVITATION

Gender-Based Differences in Heart Failure Hospitalizations Among Patients With Heart Failure Treated With SpironolactoneNCT06641284 · 2023-10-01

A Study to Improve Physician-Youth Communication and Medical Decision MakingNCT05835063 · 2023-09-14

Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe PatientsNCT05575336 · 2023-02-01

Gender-based Differences in the Outcome of Treatment With Aldosterone Antagonists in Patients With Heart FailureNCT06233695 · 2022-10-15

Implementation and Cost-evaluation of a Smartphone-based Telemonitoring and Digital Support in Patients With HFNCT05487365 · 2022-05-21

Biomarker Study: Heart Failure Patients at RiskNCT05336175 · 2022-04-01

CMR T1 Mapping for Diagnosis of Cardiac AmyloidosisNCT04862273 · 2021-04-01

Ivabradine in Stage D Heart Failure Patients on Chronic InotropesNCT03631654 · 2020-10-01

Mechanistic Studies of Nicotinamide Riboside in Human Heart FailureNCT04528004 · 2020-09-26

ACTIVE_NOT_RECRUITING

Mid-Q Response StudyNCT04180696 · 2020-01-23

Family Palliative and End-of-Life Care for Advanced Heart FailureNCT04153890 · 2020-01-13

Clinical Study to Evaluate the Predictive Value of the Heart Failure Questionnaire (HF-Q) for the Occurrence of Μajor Αdverse Cardiovascular Events (MACE) in Patients With Symptomatic Heart FailureNCT03947853 · 2019-10-01

Exergaming in Advanced HF With Multiple Chronic Conditions Prior to LVAD Implantation or Heart TransplantNCT03580759 · 2019-03-01

Impact of Sacubitril/Valsartan on Quality of Life and Mortality of CKD vs Non-CKD in Heart Failure PatientsNCT04218435 · 2019-01-01

HEart fAiluRe evaluaTion QuestionnaireNCT03895073 · 2018-09-01

Hemodynamic-GUIDEd Management of Heart FailureNCT03387813 · 2018-03-15

Future Patient - Telerehabilitation of Heart Failure PatientsNCT03388918 · 2016-12-21

Feasibility Study of the Intravascular Ventricular Assist System (iVAS)NCT02645539 · 2016-04-01

Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusionNCT03592836 · 2013-05-01

Remission From Stage D Heart FailureNCT01774656 · 2013-01-01

Severe Heart Failure and Homebased Rehabilitation - An Intersectoral Randomized Controlled TrialNCT01669395 · 2012-09-01

Epidemiology and Prognostic of the Acute Heart FailureNCT02880358 · 2011-01-01

Common interventions

1-minute sit-to-stand testDIAGNOSTIC_TEST1 6-minute walking test (6MWT)OTHER1 99mTc-DPD scintigraphyDIAGNOSTIC_TEST1 aCRT OFFDEVICE1 aCRT ONDEVICE1 ADLIFE interventionOTHER1 Angiotensin 1-7DRUG1 Attention ControlOTHER1 Blood sampling (NT-proBNP)DIAGNOSTIC_TEST1 Cardiac biopsyPROCEDURE1 CardioMEMS™ HF SystemDEVICE1 Completing a quality of life (QOL)-questionnaireOTHER1 Comunicare Solutions Smartphone ApplicationDEVICE1 Early homebased rehabilitation after hospital admissionOTHER1 Epicardial AAMs-patch transplantationPROCEDURE1 Epicardial collagen-based patch transplantationPROCEDURE1 FamPALcareBEHAVIORAL1 healthy volunteersOTHER1 HF-FamPALhomeCAREBEHAVIORAL1 intravascular ventricular assist system (iVAS)DEVICE1 iPSC-CLBIOLOGICAL1 IvabradineDRUG1 Laboratory screening for multiple myeloma / AL amyloidosisDIAGNOSTIC_TEST1 Late-gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMRI)DIAGNOSTIC_TEST1 Left ventricular assist device (LVAD)DEVICE1

Leading sponsors

University of Washington2 West Virginia University2 Aalborg University1 Abbott Medical Devices1 Ahmad Abdullah Salawi1 Alexandria University1 Biosistemak Institute for Health Systems Research1 Central Hospital, Nancy, France1 Centro Universitário Augusto Motta1 Clinision1 Comunicare Solutions SA1 Elpen Pharmaceutical Co. Inc.1 HeartWorks, Inc.1 Hospital District of Helsinki and Uusimaa1 John Parissis1

Trial status mix

COMPLETED13

UNKNOWN6

RECRUITING5

ACTIVE_NOT_RECRUITING2

NOT_YET_RECRUITING2

WITHDRAWN2

ENROLLING_BY_INVITATION1

Phase mix

NA14

PHASE14

PHASE22

PHASE42

EARLY_PHASE11

PHASE31

How to interpret this record

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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.