Condition

Cardiogenic Shock

ClinicalTrials.gov condition label

Clinical trials72

Recruiting27

Common interventions25

Lead sponsors shown15

Clinical trials

60 shown

Randomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic ShockNCT07583446 · 2026-09-09

COMPARE-VENT Feasibility Pilot StudyNCT07656259 · 2026-07-01

Prolonged Nasogastric Administration of Ketones in Decompensated Heart FailureNCT07527156 · 2026-04-04

Empagliflozin's Microcirculatory Effects in Cardiogenic Shock: an Ancillary Pilot Study of the EMPASHOCK TrialNCT07141355 · 2025-12-12

Magenta Elevate™ Clinical Feasibility Study in Cardiogenic ShockNCT07293923 · 2025-11-05

BEAT-SHOCK RegistryNCT07643610 · 2025-10-01

Clinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic ShockNCT07825363 · 2025-06-17

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp SystemNCT06080074 · 2025-04-15

Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock PatientsNCT06862700 · 2025-02-26

Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function.NCT05879276 · 2024-12-16

Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurENCT07515508 · 2024-08-07

Changes in Skeletal Muscle Thickness in Patients With Acute Heart FailureNCT06253104 · 2024-02-19

Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEFNCT06078436 · 2024-01-01

Naples Federico II Intensive Cardiac Care Unit Registry (Naples FED2-ICCU Registry)NCT06162247 · 2023-11-20

Cardiac Power Output in Cardiogenic Shock PatientsNCT05700617 · 2023-07-06

Effect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic ShockNCT04020263 · 2023-07-03

Study of Patients Admitted to a Cardiac Intensive Care Unit With Acute CardioVascular DiseaseNCT06081205 · 2023-04-27

Role of Candidate Proteins in Capillary Leakage During Acute Circulatory FailureNCT05586282 · 2023-03-20

Temporary MCS With the iVAC 2L Transaortic Device in High-risk PCINCT07149714 · 2023-02-17

Pharmacological and Mechanical Support Approaches in the Management of Acute Heart Failure in the Regional Network Model for the Management of Cardiogenic ShockNCT06827314 · 2022-12-06

Pulmonary Artery Catheter in Cardiogenic Shock TrialNCT05485376 · 2022-08-23

CytOSorb TreatMent Of Critically Ill PatientS RegistryNCT05146336 · 2022-06-22

Assessment of ECMO in Acute Myocardial Infarction Cardiogenic ShockNCT04184635 · 2021-10-14

Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock TrialNCT04419480 · 2020-12-31

Characterisation of phenotYpes in aCute Heart faiLure patiEntsNCT07508891 · 2019-03-01

Cardiogenic Shock Working Group RegistryNCT04682483 · 2017-12-04

China Extracorporeal Life Support RegistryNCT04158479 · 2017-01-01

CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic ShockNCT07461961 · 2026-10-01

NOT_YET_RECRUITING

Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic ShockNCT07762560 · 2026-10-01

NOT_YET_RECRUITING

INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac RecoveryNCT06965504 · 2026-09-01

NOT_YET_RECRUITING

Prognostic Value Enhancement Of Sequential Organ Failure Assessment )SOFA( Score by Neutrophil-Lymphocyte Ratio and Red Cell Distribution Width in Cardiogenic Shock Patients.NCT07773597 · 2026-08-30

NOT_YET_RECRUITING

Oxygen Delivery Index (ODIN) StudyNCT07601828 · 2026-05-01

NOT_YET_RECRUITING

Routine Versus Provisional Distal Perfusion Catheter Placement in Patients Undergoing Mechanical Circulatory SupportNCT07482865 · 2026-05-01

NOT_YET_RECRUITING

The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in MartiniqueNCT07351435 · 2026-02-01

NOT_YET_RECRUITING

Hemodynamic Evaluation of Left Atrial Pressure in Relationship to Pulmonary Capillary Wedge Pressure in Cardio Thoracic PatientsNCT07163052 · 2025-09-01

NOT_YET_RECRUITING

Effect of Early Empagliflozin Initiation in Cardiogenic Shock.NCT07450417 · 2025-03-10

ACTIVE_NOT_RECRUITING

REMAP ECMO - Beta Receptor Modulation TrialNCT06522594 · 2024-06-01

Clinical Effects of Intra-aortic Balloon Support in Early Acute Coronary Syndrome and Non-Acute Coronary Syndrome Related Cardiogenic ShockNCT06414187 · 2024-06-01

NOT_YET_RECRUITING

The Usefulness of Myocardial Work IndeX in ExtraCorporeal Membrane Oxygenation PatientsNCT05838937 · 2024-06-01

The RECOVER IV TrialNCT05506449 · 2023-10-28

Unloading in Heart Failure Cardiogenic ShockNCT05064202 · 2023-10-01

NOT_YET_RECRUITING

Influence of Enteral Microbiome on Mortality of Patients With Cardiogenic ShockNCT06006754 · 2023-08-30

Ivabradine Effects in Cardiogenic Shock Requiring Inotropic SupportNCT05594342 · 2022-07-01

REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)NCT05788211 · 2022-01-01

NIVIA-HemodynamicsNCT06330597 · 2021-07-17

ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic ShockNCT05027529 · 2021-05-21

Feasibility and Safety of Total Percutaneous Closure of Femoral Arterial Access Sites in the Veno-arterial ECMO PatientsNCT04689451 · 2021-02-01

ECLS Versus IMPELLA™ as Bridge to LVAD (ECI-BLAD)NCT04480151 · 2021-01-20

Innovative Technologies for the Treatment of Pulmonary and Heart FailureNCT05090930 · 2021-01-01

The Safety and Efficacy of Istaroxime for Pre-Cardiogenic ShockNCT04325035 · 2020-09-28

SURPASS Impella 5.5 StudyNCT05100836 · 2020-09-21

Pressure Volume LoopNCT04478188 · 2020-08-01

Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic ShockNCT04369573 · 2020-05-04

Comparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac OutputNCT04206865 · 2019-11-25

Cardiogenic Shock Registry MannheimNCT05575856 · 2019-06-01

Left Ventricular Volume Index in the Adjustment of Initial Dose of Dobutamine in Heart Failure and Cardiogenic ShockNCT03727282 · 2019-01-02

Levosimendan for Veno-arterial ECMO WeaningNCT04323709 · 2019-01-01

Veno-arterial Extracorporeal Membrane Oxygenation Prior to Left Ventricular Assist Device Implantation.NCT03583970 · 2018-07-05

Ultrasound Study of the Diaphragm Evolution Under ECMONCT03736239 · 2018-06-15

Efficacy and Safety on Heart Rate Control With Ivabradine on Cardiogenic ShockNCT03437369 · 2018-05-01

Common interventions

PlaceboDRUG4 LevosimendanDRUG3 Pulmonary artery catheterDEVICE3 standard of careOTHER3 CytoSorbDEVICE2 ECMODEVICE2 Impella 5.5DEVICE2 istaroximeDRUG2 1:1 Randomization to receive milrinoneDRUG1 Acute Mechanical Circulatory Support DevicesDEVICE1 adjust dobutamine according to the attending physicianPROCEDURE1 adjust dobutamine according to the ejection volume indexPROCEDURE1 Admission in the Cardiac Intensive Care Unit (CICU)OTHER1 BivalirudinDRUG1 BodyMetrix Body Composition UltrasoundDIAGNOSTIC_TEST1 Cardiohelp device (VA-ECMO)DEVICE1 CardioMEMS implantation with routine ambulatory pulmonary artery pressure monitoring and medication optimizationDEVICE1 Conventional hemodynamic monitoringPROCEDURE1 CytoSorb (CytoSorbents Corp., USA) - an extracorporeal cytokine adsorberDEVICE1 Data analysisOTHER1 Data collectionOTHER1 Distal perfusion catheter insertionPROCEDURE1 DobutamineDRUG1 DOBUTamine Injectable SolutionDRUG1 Early intra-aortic balloon pump (IABP) implantationCOMBINATION_PRODUCT1

Leading sponsors

Central Hospital, Nancy, France4 Abiomed Inc.3 Erasmus Medical Center3 Tufts Medical Center3 Amsterdam UMC, location VUmc2 Assistance Publique - Hôpitaux de Paris2 Nanjing Medical University2 University Hospital, Bordeaux2 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)1 Association Pro-arte1 Beijing Anzhen Hospital1 Brigham and Women's Hospital1 Cedars-Sinai Medical Center1 Christian Schulze1 Columbia University1

Trial status mix

RECRUITING27

UNKNOWN17

COMPLETED12

NOT_YET_RECRUITING10

TERMINATED4

ACTIVE_NOT_RECRUITING1

WITHDRAWN1

Phase mix

NA20

PHASE26

PHASE46

PHASE35

EARLY_PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.