Condition

Ocular Hypertension

ClinicalTrials.gov condition label

Clinical trials522
Recruiting19
Common interventions25
Lead sponsors shown15

Clinical trials

60 shown
Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma SuspectsNCT04401982 · 2026-07-02
RECRUITING
Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular HypertensionNCT07588152 · 2026-06-05
RECRUITING
DSLT for Reducing Medication in GlaucomaNCT07390890 · 2026-02-10
RECRUITING
Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication UseNCT07217678 · 2026-02-09
RECRUITING
Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular HypertensionNCT07335211 · 2026-01-01
RECRUITING
[KJ-TFC-005] Phase 3 Study, Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-Angle Glaucoma or Ocular HypertensionNCT07662759 · 2025-12-09
RECRUITING
24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension PatientsNCT07325240 · 2025-11-21
RECRUITING
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)NCT07218796 · 2025-10-28
RECRUITING
Implementing AI-based Glaucoma Screening Within Federally Qualified Health CentersNCT06629649 · 2025-10-22
RECRUITING
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)NCT07218783 · 2025-10-15
RECRUITING
Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus TonometryNCT04024293 · 2025-10-01
RECRUITING
Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on GlaucomaNCT07119580 · 2025-07-08
RECRUITING
Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract SurgeryNCT07036510 · 2025-06-12
RECRUITING
Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) ShuntNCT06691555 · 2024-11-08
RECRUITING
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.NCT05401357 · 2022-06-29
RECRUITING
Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority TrialNCT05844384 · 2022-03-17
RECRUITING
Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical ProstaglandinsNCT05039684 · 2021-10-01
RECRUITING
Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet CellsNCT04957329 · 2021-09-01
RECRUITING
Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy SubjectsNCT03870230 · 2017-12-01
RECRUITING
Changes in Intraocular Pressure After Intravitreal InjectionNCT07826286 · 2026-10-01
NOT_YET_RECRUITING
Evaluation of the Safety, Efficacy, Dose Response of the Bimatoprost Drug Ring System (BIM-DRS) in Pseudophakic Patients Diagnosed With Open Angle Glaucoma or Ocular HypertensionNCT07641296 · 2026-07-31
NOT_YET_RECRUITING
Dorzolamide/Brimonidine/Timolol Impact on Ocular Surface, Glaucoma Progression & Chatbot Follow-up: GLAUCO-TECHNCT07690397 · 2026-06-10
ACTIVE_NOT_RECRUITING
Efficacy and Safety of DNN.31.19.026 for Ocular Hypertension or Primary Open-Angle GlaucomaNCT07617532 · 2026-06-01
NOT_YET_RECRUITING
An Observational Study to Evaluate the ETX-4143 Device in Subjects With Ocular HypertensionNCT06709300 · 2026-01-01
WITHDRAWN
GLAUcoma Diagnostic and Imaging Analysis (GLAUDIA) StudyNCT07210216 · 2025-10-01
NOT_YET_RECRUITING
Reformulated PG324 Ophthalmic Solution for Intraocular Pressure ReductionNCT07082816 · 2025-09-02
COMPLETED
This Follow-up Extension Study is Aimed to Monitor the Long-term IOP-lowering Performance/Efficacy and Safety of the MINT® Procedure in Open Angle Glaucoma Eyes.NCT07081347 · 2025-06-16
ACTIVE_NOT_RECRUITING
Evaluate Efficacy and Safety of PA5108 Ocular Implants in Primary Open Angle Glaucoma or Ocular HypertensionNCT06964191 · 2025-05-31
ACTIVE_NOT_RECRUITING
Prophylactic Use of Timolol Maleate to Prevent Intraocular Pressure Elevation After Nd:YAG Laser Posterior CapsulotomyNCT07729189 · 2025-03-10
COMPLETED
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP MonitoringNCT06689696 · 2025-02-19
COMPLETED
Selective, Micropulse and Pattern Laser Trabeculoplasty in Medically Treated Open-angle Glaucoma.NCT07756411 · 2025-02-01
COMPLETED
Long-term Outcomes of Glaucoma Surgery in a Real-life Setting: the Agora Registry StudyNCT06829810 · 2025-01-15
COMPLETED
A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in ChinaNCT06666855 · 2024-11-28
ACTIVE_NOT_RECRUITING
Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive PatientsNCT06827535 · 2024-11-14
ENROLLING_BY_INVITATION
Open-Label Study of Safety of H1337 in Healthy VolunteersNCT06572397 · 2024-09-16
COMPLETED
Next Generation RocklatanNCT06441643 · 2024-09-04
COMPLETED
Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCTNCT06498440 · 2024-09-01
UNKNOWN
Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular HypertensionNCT06394973 · 2024-08-05
COMPLETED
The A D A G I O StudyNCT06455683 · 2024-06-01
NOT_YET_RECRUITING
Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular HypertensionNCT04500574 · 2024-04-03
TERMINATED
A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both EyesNCT06267274 · 2024-04-01
UNKNOWN
Direct Selective Laser Trabeculoplasty in Ethnic Chinese PopulationNCT05902871 · 2024-03-11
ACTIVE_NOT_RECRUITING
EVALUATION of CATS TONOMETER PRISM in LASIK SUBJECTSNCT06266351 · 2024-02-12
COMPLETED
A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular HypertensionNCT06177678 · 2024-02-01
UNKNOWN
Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular HypertensionNCT06152861 · 2023-11-15
UNKNOWN
Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Eye PressureNCT06144918 · 2023-11-09
COMPLETED
Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic SolutionNCT06120842 · 2023-10-13
ACTIVE_NOT_RECRUITING
Travoprost Intraocular Implant in Conjunction With Cataract SurgeryNCT06061718 · 2023-09-11
UNKNOWN
Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionNCT05913232 · 2023-08-28
COMPLETED
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL CombinationNCT07154810 · 2023-03-16
ACTIVE_NOT_RECRUITING
Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and SafetyNCT05857267 · 2023-03-07
COMPLETED
Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP)NCT05495269 · 2022-11-23
COMPLETED
Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With GlaucomaNCT05273385 · 2022-10-10
TERMINATED
Safety and Effectiveness of Drop-free Small Incision Cataract SurgeryNCT05248139 · 2022-10-01
UNKNOWN
A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular HypertensionNCT05456724 · 2022-08-04
UNKNOWN
Safety Assessment of T4090 Eye Drops in Ocular Hypertensive or Glaucomatous Patients.NCT05389267 · 2022-07-05
ACTIVE_NOT_RECRUITING
Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous PatientsNCT05397600 · 2022-06-22
COMPLETED
A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular HypertensionNCT04140279 · 2022-05-13
WITHDRAWN
Evaluation of the Safety and Effectiveness of the Bimatoprost Implant System / IOL Combination in Patients With Ocular Hypertension or Mild to Moderate Open-angle GlaucomaNCT07154797 · 2022-04-21
COMPLETED
A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)NCT05335122 · 2022-03-16
COMPLETED

Common interventions

LatanoprostDRUG17PlaceboDRUG17XalatanDRUG11BimatoprostDRUG10latanoprost 0.005%DRUG10timololDRUG10XalacomDRUG10bimatoprost 0.01%DRUG8Bimatoprost 0.01% ophthalmic solutionDRUG8Latanoprost 0.005% Ophthalmic SolutionDRUG8timolol 0.5%DRUG8latanoprost ophthalmic solution 0.005%DRUG7AR-13324 Ophthalmic Solution 0.02%DRUG6Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspensionDRUG6VehicleDRUG6Bimatoprost 0.03%DRUG5Bimatoprost SRDRUG5Latanoprost ophthalmic solution 0.005% (XALATAN®)DRUG5PlaceboOTHER5Selective laser trabeculoplastyPROCEDURE5timolol maleateDRUG5timolol maleate 0.5%DRUG5Timolol Maleate Ophthalmic Solution 0.5% BIDDRUG5Timolol maleate ophthalmic solution, 0.5%DRUG5TravatanDRUG5

Trial status mix

COMPLETED400
UNKNOWN41
TERMINATED22
WITHDRAWN20
RECRUITING19
ACTIVE_NOT_RECRUITING12
NOT_YET_RECRUITING5
ENROLLING_BY_INVITATION2
SUSPENDED1

Phase mix

PHASE3138
PHASE2121
PHASE4107
NA55
PHASE149

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.