Condition

Parkinson

ClinicalTrials.gov condition label

Clinical trials67

Recruiting7

Common interventions25

Lead sponsors shown15

Clinical trials

60 shown

Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior DisorderNCT07217054 · 2025-11-04

The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological ConditionsNCT07786116 · 2025-11-01

Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's DiagnosisNCT07204652 · 2025-09-03

Optimistic and Pessimistic Dopamine Signals in the Human Brain: a Mapping and Modelling Study in Health and Parkinson's DiseaseNCT07402928 · 2025-06-02

Mediterranean Diet Effects on Parkinson's DiseaseNCT06705517 · 2025-01-17

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's DiseaseNCT06680830 · 2025-01-17

Neurologic Stem Cell Treatment StudyNCT02795052 · 2016-06-01

Driving Performance in Parkinson's Disease and Multiple Sclerosis Using a Driving SimulatorNCT07809828 · 2026-11-01

NOT_YET_RECRUITING

Transforming Parkinson's Care With Predictive AlgorithmsNCT06755645 · 2026-09-01

NOT_YET_RECRUITING

Comparing Biomarker-Guided DBS Programming With Standard Clinical Monopolar ProgrammingNCT07369310 · 2026-03-01

NOT_YET_RECRUITING

Effects of Otago and Frenkel's Exercises on Strengthening of Antigravity Muscles in Parkinson's Disease.NCT07277699 · 2025-08-18

The Brain&Senses StudyNCT06991816 · 2025-08-01

ACTIVE_NOT_RECRUITING

Which Tools Better Predict Fall Risk in Parkinson's Disease: A Comparative Study of Objective, Self-Reported, and Functional Balance AssessmentNCT07148700 · 2025-05-01

Validity and Reliability of the Standing Up From Supine Test With Parkinson's PatientsNCT06859385 · 2025-02-01

ENROLLING_BY_INVITATION

Effects of Transcranial Pulse Stimulation in Parkinson's DiseaseNCT06676995 · 2024-12-31

Digital BIOmarkers for the Assessment of Motor Status in Parkinson's Disease Patients with CLInical and ThErapeutic ApplicationNCT06817772 · 2024-12-09

ENROLLING_BY_INVITATION

Impact of Ketoflex 12/3 Diet on Parkinson's Disease Symptoms: A Clinical StudyNCT06892418 · 2024-03-30

Digitised Home Based Care for Parkinson's DiseaseNCT05544305 · 2024-01-01

Clinical Investigation of NMS AssistNCT05414071 · 2023-12-01

A Pilot Comparative Bioavailability Study of Levodopa Administered Via Levodopa Cyclops® Relative to INBRIJA®NCT06037590 · 2023-09-25

Results of Combined Medical and Swallowing Behavioral Readjustment Therapy in Oropharyngeal Dysphagia Management Among Parkinson's PatientsNCT07618637 · 2023-08-30

Virtual Reality and Fear of Falling in Parkinson's DiseaseNCT05931692 · 2023-07-17

Posture Exercises in Parkinson's DiseaseNCT06848257 · 2023-07-15

ENROLLING_BY_INVITATION

Randomized Controlled Study Evaluating the Efficacy of Hypnosis in Nuclear MedicineNCT06116084 · 2023-05-26

GRoningen Early-PD Ambroxol TreatmentNCT05830396 · 2023-05-01

Detecting the Rest Tremor Associated With Parkinson's Disease Using Analysis of the Muscle Contractions RhythmicityNCT05998486 · 2023-04-03

Super-resolution of Brain Magnetic Resonance Images in Deep Brain Stimulation for Parkinson's DiseaseNCT05596201 · 2023-03-28

Sensorimotor Integration in Monogenic Parkinson-dystonia SyndromesNCT05713721 · 2023-01-01

Serious Games for Parkinson's DiseaseNCT05551338 · 2022-06-15

Comparison of Propioceptive Neuromuscular Facilitation Vs Balance Exercise Along With Conventional Therapy for Balance and Gait in Chronic Parkinson's PatientNCT05405933 · 2022-06-01

Choral Singing for Patients With Parkinson'sNCT05379062 · 2022-05-01

Impact of Exercise on Muscle Metabolism and Function for Persons With ParkinsonsNCT07720713 · 2022-04-27

The Effect of Exercise in Water on Functional Fitness in People With Parkinson's DiseaseNCT05737992 · 2022-04-10

Positive Psychological Intervention for Parkinson's Disease PatientsNCT06832358 · 2022-02-01

The Relationship of Spine Posture and Mobility With Upper Extremity Functions in Parkinson's PatientsNCT05119803 · 2021-11-03

Treatment Burden in Parkinson'sNCT04769973 · 2021-06-22

Early ParkinSon wIth L-DOPA/DDCI and OpicapoNe (EPSILON Study)NCT04978597 · 2021-05-31

Improving Walking With Heel-To-Toe DeviceNCT04300348 · 2021-04-15

Neuroplasticity in Parkinson's DiseaseNCT05286736 · 2021-03-01

tDCS of the Primary Motor Cortex to Improve Implicit Motor Sequence Learning in Parkinson's DiseaseNCT04606979 · 2020-10-11

Autologous Stem/Stromal Cells in Neurological Disorders and DiseaseNCT03297177 · 2020-01-01

State-dependent Pathophysiological Oscillations in Parkinson's Disease and Treatment With DBS Using the Medtronic RC+SNCT04011449 · 2019-09-01

123 I-FP-CIT SPECT Prescriptions for Parkinsonian SyndromesNCT05698784 · 2019-06-01

Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's DiseaseNCT04566341 · 2019-05-04

ENROLLING_BY_INVITATION

Study of the Efficacy of N-acetylcysteine (NAC) on Impulse Control DisordersNCT03146130 · 2019-01-23

Studies of Brain and Body InteractionNCT03672266 · 2018-08-01

The Effect of Deep Brain Stimulation on Facial Expressions.NCT03558568 · 2018-05-01

A Study in Patients With Advanced Parkinson's Disease to Assess the Relative Bioavailability of Levodopa Administered as ND0612 Subcutaneous Infusion Versus Levodopa Administered as Carbidopa-Levodopa Enteral SuspensionNCT03462043 · 2018-04-10

Action Observation Treatment in Parkinson's PatientsNCT04181918 · 2018-03-26

The Effect of Cognitive Functions on Upper Extremity Functionality in Parkinson's PatientsNCT05872646 · 2018-02-08

Cerebellar rTMS Theta Burst for Dual-task Walking in Parkinson's DiseaseNCT04238000 · 2018-01-01

Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease.NCT03232996 · 2017-11-01

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation CarriersNCT03234478 · 2017-07-01

EMG Modules as a Novel Biomarker of Basal Ganglia Plasticity in Parkinson's DiseaseNCT02896816 · 2016-08-01

Buspirone Treatment of Iatrogenic Dyskinesias in Advanced Parkinson' DiseaseNCT02617017 · 2016-06-17

Evaluation of Myocardial Sympathetic Denervation in Parkinson's Disease Using [18F]FDOPANCT02495649 · 2015-08-01

Thoracic Spinal Cord Stimulation as a Symptomatic Treatment for Advanced Parkinson's DiseaseNCT02539784 · 2015-06-01

Prism Adaptation Treatment of Parkinson's DiseaseNCT02380859 · 2015-02-01

Development of a Monitoring Set-up and Algorithm Using Functional MRI (fMRI) and EEG for Prediction of Response to Repetitive Deep Transcranial Magnetic Stimulation (rDTMS) for Patients With Parkinson's DiseaseNCT02249715 · 2014-11-01

Suprapostural Attention Focus and Postural Difficulty on H-reflex and Brain Activity: Aging and Parkinson's DiseaseNCT02539446 · 2014-10-01

Common interventions

PlaceboDRUG3 Deep Brain StimulationDEVICE2 [18F]-DOPAOTHER1 1x1 Low Intensity Transcranial Direct Current Stimulation (tDCS)DEVICE1 24 hours drug withdrawal of dopaminergic medicationOTHER1 A series of questionnairesBEHAVIORAL1 Activa PC+SDEVICE1 Active Singing GroupBEHAVIORAL1 Ambroxol HydrochlorideDRUG1 AOTBEHAVIORAL1 attentional focusBEHAVIORAL1 Balance ExerciseDIAGNOSTIC_TEST1 Brainsway Multiway deep TMS device (two channels)DEVICE1 BuspironeDRUG1 Centricyte 1000DEVICE1 CLESCOMBINATION_PRODUCT1 clinical assessmentDIAGNOSTIC_TEST1 combined pharmaceutical treatment and rehabilitation techniquesBEHAVIORAL1 Computer game based balance and walking rehabilitation for individuals with Parkinson's DiseaseOTHER1 Control interventionOTHER1 Conventional DBS Programming (Monopolar Review)DEVICE1 Digital Home Based Care pathwayOTHER1 ElectroencephalogramDIAGNOSTIC_TEST1 ElectromyographyDIAGNOSTIC_TEST1 EMG in wrist flexor-pronators and extensor-supinatorsDIAGNOSTIC_TEST1

Leading sponsors

Assistance Publique - Hôpitaux de Paris3 CND Life Sciences2 Rutgers, The State University of New Jersey2 Spaulding Rehabilitation Hospital2 Tel-Aviv Sourasky Medical Center2 University of Minnesota2 University of Plymouth2 Ahram Canadian University1 Bezmialem Vakif University1 Bial - Portela C S.A.1 Central Hospital, Nancy, France1 Centre Hospitalier Universitaire, Amiens1 Danish Research Centre for Magnetic Resonance1 Dartmouth-Hitchcock Medical Center1 First Affiliated Hospital of Wenzhou Medical University1

Trial status mix

COMPLETED31

UNKNOWN16

RECRUITING7

ENROLLING_BY_INVITATION4

NOT_YET_RECRUITING3

WITHDRAWN3

TERMINATED2

ACTIVE_NOT_RECRUITING1

Phase mix

NA35

PHASE35

PHASE24

PHASE13

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.