Condition

Small Cell Lung Carcinoma

ClinicalTrials.gov condition label

Clinical trials103
Recruiting21
Common interventions25
Lead sponsors shown15

Clinical trials

60 shown
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory DiseaseNCT07509034 · 2026-10-12
RECRUITING
MDT-Based Umbrella Decision Model for Geriatric Lung Cancer PatientsNCT07509333 · 2026-04-05
RECRUITING
Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized TrialNCT07015892 · 2026-03-01
RECRUITING
Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)NCT07155200 · 2025-12-18
RECRUITING
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid TumorsNCT07006727 · 2025-10-16
RECRUITING
A Study of LY4175408 in Participants With Advanced CancerNCT07046923 · 2025-07-28
RECRUITING
A Study of Hospital-at-Home for People Receiving TarlatamabNCT06957314 · 2025-04-23
RECRUITING
Prospective, Longitudinal Biocollection in Thoracic Oncology, Including Newly Diagnosed Lung Cancer PatientsNCT06481813 · 2024-12-10
RECRUITING
A Study With NKT3964 for Adults With Advanced/Metastatic Solid TumorsNCT06586957 · 2024-09-19
RECRUITING
Radiotherapy Strategies for Use in Combined Treatment of Small-cell Lung CancerNCT06529081 · 2024-04-01
RECRUITING
PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.NCT06247163 · 2024-02-22
RECRUITING
A Study of SGN-CEACAM5C in Adults With Advanced Solid TumorsNCT06131840 · 2023-11-20
RECRUITING
A Phase IIII Study of AL8326 in Small Cell Lung CancerNCT06247605 · 2023-10-26
RECRUITING
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine CancersNCT05882058 · 2023-10-13
RECRUITING
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung CancerNCT05620342 · 2023-06-21
RECRUITING
Biology of Young Lung Cancer Study: The YOUNG LUNG StudyNCT05265429 · 2023-01-01
RECRUITING
Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung CancerNCT05450965 · 2022-07-19
RECRUITING
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the BrainNCT05419076 · 2022-06-10
RECRUITING
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)NCT04585750 · 2020-10-29
RECRUITING
PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56NCT04199741 · 2019-12-11
RECRUITING
Molecular Analysis and Treatment Options of SCLCNCT05945745 · 2016-01-01
RECRUITING
A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.NCT07623642 · 2026-06-02
NOT_YET_RECRUITING
Exploration of Treatment Strategies After Concurrent Chemoradiotherapy for LS-SCLC Guided by MRDNCT07357532 · 2026-01-31
NOT_YET_RECRUITING
An Exploratory Study of Lurbinectedin With Radiotherapy in SCLC With Single-lesion Progression After First Course TreatmentNCT06501976 · 2025-12-31
ACTIVE_NOT_RECRUITING
Durvalumab After Chemoradiotherapy in Limited Stage Small Cell Lung Cancer.NCT06992609 · 2025-09-15
ACTIVE_NOT_RECRUITING
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BMS-986489 in Chinese Participants With Relapsed/Refractory Small Cell Lung CancerNCT06799286 · 2025-05-07
COMPLETED
Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC)NCT06419179 · 2024-10-09
ENROLLING_BY_INVITATION
REAL-WORLD DURVALUMAB IN EXTENSIVE-STAGE SMALL CELL LUNG CANCERNCT06826677 · 2024-07-30
COMPLETED
A Study With NKT3447 for Adults With Advanced/Metastatic Solid TumorsNCT06264921 · 2024-02-23
TERMINATED
Adebrelimab and Concurrent Radiochemotherapy as First-line Treatment for Extensive-stage Small-cell Lung CancerNCT06236997 · 2024-02-10
NOT_YET_RECRUITING
A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLCNCT06177925 · 2023-12-10
UNKNOWN
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable CancersNCT05582031 · 2023-04-30
WITHDRAWN
ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung CancersNCT05616624 · 2023-04-05
TERMINATED
Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the ThoraxNCT05617963 · 2023-03-24
ACTIVE_NOT_RECRUITING
Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)NCT05049863 · 2023-02-27
TERMINATED
FASTing-like Approach and Maintenance IMMunotherapy in ES-SCLC Patients Not Progressing on Chemoimmunotherapy InductionNCT05703997 · 2023-01-01
NOT_YET_RECRUITING
A French Real-life Study: EvaluatioN of durvALumab Utilization and Effectiveness for First Line Extensive Stage Small Cell Lung Cancer.NCT05683977 · 2022-11-14
ACTIVE_NOT_RECRUITING
A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.NCT05329623 · 2022-05-03
COMPLETED
Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)NCT05224141 · 2022-03-24
ACTIVE_NOT_RECRUITING
KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung CancerNCT05027867 · 2021-12-06
TERMINATED
Surufatinib Combined With Chemotherapy Plus Toripalimab or Not in the Treatment of Small Cell Lung CancerNCT04996771 · 2021-11-09
UNKNOWN
Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)NCT04938817 · 2021-08-19
ACTIVE_NOT_RECRUITING
Camrelizumab Plus Apatinib as Maintenance Therapy in Extensive-stage Small-cell Lung CancerNCT04901754 · 2021-07-14
UNKNOWN
Searching for Predictive Biomarkers of Efficacy in Small Cell Lung Cancer Patients Treated With Chemotherapy-immunotherapy Combination Using Imaging Mass Cytometry (HYPE)NCT06558903 · 2021-06-24
UNKNOWN
Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid TumorsNCT04902872 · 2021-05-03
COMPLETED
Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung CancerNCT04665856 · 2020-12-21
COMPLETED
A Phase Ib/III Clinical Study to Evaluate the Efficacy and Safety of IBI318 in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel in Patients With Small Cell Lung Cancer Who Have Failed First-line or Above ChemotherapiesNCT04672928 · 2020-12-14
COMPLETED
Tislelizumab in Combination With Anlotinib With ES-SCLC as Maintenance Therapy After First Line ChemotherapyNCT04620837 · 2020-11-01
UNKNOWN
A Study of Durvalumab Plus Tremelimumab With Chemotherapy in Untreated ES-SCLCNCT03963414 · 2020-09-25
TERMINATED
Lurbinectedin (PM01183) Combined With Pembrolizumab in Small Cell Lung Cancer.NCT04358237 · 2020-09-21
COMPLETED
A Study of Sequential Therapy of Camrelizumab Combined With Chemotherapy（Irinotecan Plus Platinum）and With Apatinib in Participants With Untreated Advanced Small Cell Lung Cancer（SCLC）NCT04453930 · 2020-06-08
UNKNOWN
First-line Chemotherapy Followed by Toripalimab Combined With Anlotinib for Maintenance in ES-SCLCNCT04363255 · 2020-05-01
UNKNOWN
Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung CancerNCT03735095 · 2020-02-12
COMPLETED
Feasibility and Safety Study of Nivolumab With Irinotecan for Small Cell Lung CancerNCT04173325 · 2020-01-06
TERMINATED
Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLCNCT03994744 · 2019-08-20
UNKNOWN
A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung CancerNCT04028050 · 2019-08-12
COMPLETED
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsNCT03849469 · 2019-05-29
COMPLETED
A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung CancerNCT03850067 · 2019-03-12
COMPLETED
A Study of Lobaplatin/Etoposide With or Without Anlotinib Maintenance Therapy in Patients With ES-SCLCNCT03700359 · 2019-03-01
UNKNOWN
Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung CancerNCT03662074 · 2018-11-07
TERMINATED

Common interventions

EtoposideDRUG13CarboplatinDRUG10CisplatinDRUG7DurvalumabDRUG6IrinotecanDRUG5AtezolizumabDRUG4PembrolizumabDRUG4placeboDRUG4Anlotinib HydrochlorideDRUG3PaclitaxelDRUG3Radiation TherapyRADIATION3AdebrelimabDRUG2GemcitabineDRUG2LurbinectedinDRUG2Roniciclib (BAY1000394)DRUG2111In-ETN029DRUG1225Ac-ETN029DRUG145 Gy in 30 fractionsRADIATION15-Fluorouracil (5-FU)DRUG160 Gy in 40 fractionsRADIATION189Zr-DFO-SC16.56DRUG1ABT-263DRUG1Adebrelimab InjectionDRUG1ADI-PEG 20DRUG1Adriamycin, cyclophosphamide, vindesine, valproic acidDRUG1

Trial status mix

COMPLETED35
RECRUITING21
TERMINATED16
UNKNOWN14
ACTIVE_NOT_RECRUITING9
NOT_YET_RECRUITING4
AVAILABLE1
ENROLLING_BY_INVITATION1
NO_LONGER_AVAILABLE1
WITHDRAWN1

Phase mix

PHASE248
PHASE142
NA9
PHASE39
EARLY_PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.