Condition
Breast Cancer Stage IV
ClinicalTrials.gov condition label
Clinical trials
51 shownA Study of Meaning-Centered Therapy for Mexican Adults With Advanced CancerNCT07225309 · 2026-05-01
RECRUITINGHERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term RemissionNCT07459673 · 2026-03-04
RECRUITINGTrastuzumab Deruxtecan in First-Line HER2-Positive Metastatic Breast Cancer With Proactive Toxicity ManagementNCT07371585 · 2026-02-18
RECRUITINGHER2-PET as a Precision Imaging Tool for Treatment With HER2-ADC in HER2-expressing mBCNCT06830382 · 2025-10-03
RECRUITINGPhase III Trial of Camrelizumab+Apatinib+Eribulin vs. Physician's Choice Chemotherapy in Advanced Triple-Negative Breast CancerNCT06889688 · 2025-02-21
RECRUITINGA Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast CancerNCT06678269 · 2024-11-15
RECRUITINGTart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced NeuropathyNCT06268665 · 2024-08-15
RECRUITINGHR+/HER2- Advanced or Metastatic Breast Cancer Patients Treated With Sacituzumab GovitecanNCT06236269 · 2024-03-15
RECRUITINGRADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 StudyNCT07030569 · 2024-02-01
RECRUITINGA Study of Pembrolizumab and Ablation (Cryoablation or Histotripsy) in People With Breast CancerNCT06246968 · 2024-01-29
RECRUITINGA Study of Oral MBQ-167 in Participants With Advanced Breast CancerNCT06075810 · 2023-11-09
RECRUITINGA Phase I/II Study of FWD1802 in Patients With ER+/HER2- Advanced BC.NCT06064812 · 2023-09-12
RECRUITINGPhase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain MetastasesNCT05866432 · 2023-07-01
RECRUITINGPredicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 StudyNCT06805812 · 2023-05-01
RECRUITINGStereotactic Ablative Radiotherapy for OligoMetastatic Breast CancerNCT05377047 · 2022-09-19
RECRUITINGSHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem CellsNCT04150042 · 2021-01-13
RECRUITINGDetecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DXd TherapyNCT06680596 · 2025-07-30
ENROLLING_BY_INVITATIONA Phase I/II Multicenter, Open-Label Study of Lu-177-DOTAGA-IAC, for the Treatment of Angiogenic Breast Cancer Patients.NCT04469127 · 2024-09-30
UNKNOWNInetetamab Combined With Paclitaxel With/Without Pertuzumab for Previously Treated HER2-positive Advanced Breast CancerNCT06578299 · 2024-08-30
NOT_YET_RECRUITINGMulti-Institutional Transgender & Gender-Diverse Breast Cancer StudyNCT06234488 · 2023-12-08
COMPLETEDDetection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or RibociclibNCT05625087 · 2023-10-19
ACTIVE_NOT_RECRUITINGClinical Study of Huaier Granules in Patients With Advanced Breast Cancer Without Visceral MetastasisNCT05860907 · 2023-10-01
NOT_YET_RECRUITINGMulticenter Study to Evaluate a Systematized Communication Model for Breast Cancer PatientsNCT05837533 · 2023-05-17
COMPLETEDRWS of Paclitaxel Liposome Combined With Anti-HER-2 Monoclonal AntibodyNCT06481553 · 2023-02-01
UNKNOWNStudy of Dotatate Imaging in Breast CancerNCT05880394 · 2023-01-10
UNKNOWNCyclin Dependant Kinase 4/6 (CDK4/6) Inhibitors as a Second Line Treatment in Metastatic Breast Cancer PatientsNCT05670054 · 2022-03-01
UNKNOWNA Study of Oleogel-S10 Gel for the Treatment of Radiation Dermatitis in People With Breast CancerNCT05190770 · 2021-12-15
COMPLETEDTucatinib With Chemotherapy and Trastuzumab in Advanced Her-2-neu Overexpressing, Previously Treated Breast Cancer.NCT04896320 · 2021-12-15
WITHDRAWNFicus Septica Leaves Fraction as a Complementary Therapy for Stadium IV Breast Cancer PatientsNCT05033925 · 2021-10-25
UNKNOWNPreventing High Blood Sugar in People Being Treated for Metastatic Breast CancerNCT05090358 · 2021-10-08
ACTIVE_NOT_RECRUITINGSitravatinib in Metastatic Breast CancerNCT04123704 · 2021-09-22
TERMINATEDA Study of Mirdametinib on Its Own or in Combination With Fulvestrant in People With Solid Tumor CancerNCT05054374 · 2021-09-14
COMPLETEDBRaziLian outcomE for metAStatic breasT CancerNCT05559528 · 2021-09-13
UNKNOWNStudy of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild CardiotoxicityNCT05036252 · 2021-08-27
ACTIVE_NOT_RECRUITINGHeat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor CellsNCT04628806 · 2021-02-17
UNKNOWNAnalysis of Therapy Sequence in Women With HR+, HER2 - mBC in Moscow: A Multicenter Retrospective Observational Study.NCT04852081 · 2021-01-01
UNKNOWNThe Benefit of Surgery in Stage IV of Breast CancerNCT04697043 · 2020-11-20
UNKNOWNRWD Study in HER2+ mBC Patients in Third-Line TherapyNCT04566458 · 2020-10-01
COMPLETEDPhase II Study of T-DX in HER2-positive Breast Cancer Brain MetastasesNCT04752059 · 2020-07-28
COMPLETEDSimvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast CancerNCT03324425 · 2020-03-04
ACTIVE_NOT_RECRUITINGLocoregional Treatment and Palbociclib in de Novo, Treatment Naive, Stage IV ER+, HER2- Breast Cancer PatientsNCT03870919 · 2019-10-23
ACTIVE_NOT_RECRUITINGClinical Outcome and Toxicity Data in Patients With Advanced Breast Cancer Treated With CDK Inhibitors Combined With Endocrine TherapyNCT04133207 · 2019-01-01
COMPLETEDSelf-Advocacy Serious Game in Advanced CancerNCT03339765 · 2018-12-13
COMPLETEDA Whole-food, Plant-Based Nutrition Intervention in Women With Metastatic Breast CancerNCT03045289 · 2018-07-05
COMPLETEDThe Resistance and Immune Response to Palbociclib in Breast CancerNCT03401359 · 2017-10-24
UNKNOWNCombination of Carboplatin, Eribulin and Veliparib in Stage IV Cancer PatientsNCT03032614 · 2017-09-30
WITHDRAWNPIPAC Nab-pac for Stomach, Pancreas, Breast and Ovarian CancerNCT03304210 · 2017-09-16
COMPLETEDTo Evaluate the Efficacy of NY-ESO-1-specific T Cell Receptor Affinity Enhancing Specific T Cell in Solid TumorsNCT03159585 · 2017-04-14
COMPLETEDRandomized Clinical Trial Evaluating the Use of the Laser-Assisted Immunotherapy (LIT/inCVAX) in Advanced Breast CancerNCT03202446 · 2016-06-13
TERMINATEDA Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast CancerNCT02448771 · 2015-07-09
COMPLETEDQuantitation of Endothelial Progenitor Cells as Markers of Tumor Angiogenesis in Breast CancerNCT00393341 · 2006-10-01
COMPLETEDCommon interventions
PalbociclibDRUG4AbemaciclibDRUG3AlpelisibDRUG3FulvestrantDRUG3RibociclibDRUG31% Glycated ChitosanDRUG1AnastrozoleDRUG1Autologous Hematopoietic Stem CellsDEVICE1BazedoxifeneDRUG1BCNUDRUG1Blood DrawPROCEDURE1Camrelizumab+Apatinib+EribulinDRUG1CanagliflozinDRUG1CarboplatinDRUG1Cardiopulmonary Exercise TestDIAGNOSTIC_TEST1Communication modelOTHER1comparing both arms as regard the objective response rate, toxicity profile, quality of life, progression free survivalDRUG1Copper-64 DOTATATEDRUG1CryoablationDEVICE1CTC isolation by HSP70DIAGNOSTIC_TEST1CyclophosphamideDRUG1Datopotamab deruxtecanDRUG1Digital Health ToolsDEVICE1EchocardiogramDIAGNOSTIC_TEST1EchocardiographyDIAGNOSTIC_TEST1
Leading sponsors
Memorial Sloan Kettering Cancer Center8UNICANCER3Fondazione IRCCS Istituto Nazionale dei Tumori, Milano2Fudan University2Medical University of Vienna2SOLTI Breast Cancer Research Group2Advanced Imaging Projects, LLC1Baylor Breast Care Center1Blokhin's Russian Cancer Research Center1Cancer Institute and Hospital, Chinese Academy of Medical Sciences1Charite University, Berlin, Germany1Dana-Farber Cancer Institute1Eske Corporation S.A.C1Exactis Innovation1Forward Pharmaceuticals Co., Ltd.1
Trial status mix
RECRUITING16
COMPLETED13
UNKNOWN10
ACTIVE_NOT_RECRUITING5
NOT_YET_RECRUITING2
TERMINATED2
WITHDRAWN2
ENROLLING_BY_INVITATION1
Phase mix
PHASE220
PHASE112
NA7
PHASE34
PHASE42
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.