Condition

Liver Cirrhosis

ClinicalTrials.gov condition label

Clinical trials121
Recruiting17
Common interventions25
Lead sponsors shown15

Clinical trials

60 shown
A Phase 2 Study of Foscenvivint in Liver Cirrhosis Patients Caused by HIV/HCV Co-infection With HemophiliaNCT07681089 · 2026-10-01
RECRUITING
Coil-Assisted Small-Diameter Covered-Stent Shunt Reduction for Refractory Hepatic Encephalopathy After TIPSNCT07799948 · 2026-09-01
RECRUITING
Austrian PBC RegistryNCT07598669 · 2026-03-18
RECRUITING
Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt PlacementNCT07439939 · 2026-03-09
RECRUITING
The Diagnostic Value of Subharmonic Imaging Technology Combined With Liver Stiffness and Platelet Count for High-risk Esophageal and Gastric Varices in Patients With Liver CirrhosisNCT07151885 · 2025-08-31
RECRUITING
Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver CirrhosisNCT07116096 · 2025-08-17
RECRUITING
Portal Inflow Modulation Prior to Liver Transplantation in Patients With Increased Risk of Intraoperative Blood LossNCT07111221 · 2025-06-24
RECRUITING
Early TIPS in Patients With Liver Cirrhosis and AscitesNCT06576934 · 2025-04-01
RECRUITING
Digital Early Warning System for Acute Lung Injury in Liver SurgeryNCT07070362 · 2024-11-01
RECRUITING
Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and MortalityNCT06338215 · 2024-05-15
RECRUITING
Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver CirrhosisNCT06265272 · 2023-12-10
RECRUITING
Freiburg TIPS RegistryNCT05782556 · 2023-01-01
RECRUITING
Relevance of Sarcopenia in Advanced Liver DiseaseNCT05502198 · 2021-02-01
RECRUITING
Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver DiseaseNCT04578301 · 2020-09-22
RECRUITING
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With CancerNCT05181826 · 2019-05-21
RECRUITING
VICIS - Vienna Cirrhosis StudyNCT03267615 · 2017-02-01
RECRUITING
Cirrhosis, Effects of TRAnsplantation and DiabetesNCT02038517 · 2013-06-01
RECRUITING
Fiber-Optic Navigation During TIPS Creation: A Prospective Pilot StudyNCT07470515 · 2027-01-01
NOT_YET_RECRUITING
Lifestyle, Dietary Patterns, and Cardiometabolic Risk in Metabolic Dysfunction-Associated Steatotic Liver Disease Among People Living With HIVNCT07861594 · 2026-11-01
NOT_YET_RECRUITING
Proximal Splenic Artery Embolization (PSAE) for the Treatment of Refractory Ascites in Decompensated CirrhosisNCT07755059 · 2026-10-01
NOT_YET_RECRUITING
Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in CirrhosisNCT07587671 · 2026-08-01
NOT_YET_RECRUITING
Long-term Efficacy and Safety of LSD Versus TIPS for Cirrhotic Portal Hypertension Bleeding and HypersplenismNCT07490405 · 2026-06-01
NOT_YET_RECRUITING
Ultrasound Prediction of Esophageal Variceal Bleeding RiskNCT07571876 · 2026-04-01
NOT_YET_RECRUITING
Heart Problems in Children With Chronic Liver DiseaseNCT07502196 · 2026-04-01
NOT_YET_RECRUITING
Pantoprazole After Prophylactic Endoscopic Variceal TreatmentNCT07248722 · 2026-03-27
ENROLLING_BY_INVITATION
Multiparametric Ultrasound for the Noninvasive Diagnosis of Porto-sinusoidal Vascular Liver DisorderNCT07492862 · 2026-03-01
NOT_YET_RECRUITING
TACE Combined With Tislelizumab, Lenvatinib, and Carvedilol for Unresectable HCC With Cirrhotic Portal HypertensionNCT07350070 · 2025-12-31
NOT_YET_RECRUITING
Effect of a Focused Point-of-care Ultrasonography Screening Protocol in Hospitalized PatientsNCT07656428 · 2025-04-05
ACTIVE_NOT_RECRUITING
Von Willebrand Factor Levels in Patients With Liver Cirrhosis and Portal HypertensionNCT06694090 · 2024-11-15
NOT_YET_RECRUITING
Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver CirrhosisNCT03130127 · 2024-07-01
UNKNOWN
A Phase 2 Trial of Foscenvivint in Liver Cirrhosis Patients Caused by HIV/HCV Co-infection With Hemophilia (OP-724-H201)NCT06144086 · 2024-05-08
COMPLETED
Clinical Evaluation of Simcyp-Guided Simvastatin Dosing in Patients With Liver CirrhosisNCT07459972 · 2024-03-15
COMPLETED
Clinical Application of Simcyp-Guided Doses of Antihypertensive Drugs in Cirrhotic PatientsNCT07397481 · 2024-03-01
COMPLETED
Colonic Polypectomy in Cirrhotic Patients With Portal HypertensionNCT06832826 · 2024-01-14
COMPLETED
A Study to Test Whether Avenciguat Helps People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) Who Had Bleeding in the Esophagus or Fluid Accumulation in the BellyNCT06082843 · 2024-01-03
TERMINATED
Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of CSPH in Patients With cACLDNCT06147947 · 2023-12-01
UNKNOWN
Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of GOV in Patients With cACLDNCT06144437 · 2023-11-01
UNKNOWN
A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver CirrhosisNCT05741372 · 2023-09-07
COMPLETED
Risk Factors for Advanced Fibrosis Among FLD PatientsNCT05971082 · 2023-08-24
UNKNOWN
A Digital Tongue Diagnosis Model for High- and Low-risk Esophagogastroduodenal Varices in CirrhosisNCT05979935 · 2023-07-01
ACTIVE_NOT_RECRUITING
Liver and Spleen Stiffness to Predict the Presence of Esaphageal Varices in Cirrhotic With Advanced HCCNCT06773260 · 2023-06-20
UNKNOWN
Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study)NCT05516498 · 2022-10-31
TERMINATED
Incidence and Predictors of Post-TIPS Heart Failure in Patients With CirrhosisNCT05596253 · 2022-10-11
UNKNOWN
Research on Optimal Strategy of Hypoglycemic Therapy for Cirrhosis With DiabetesNCT05641337 · 2022-10-01
UNKNOWN
Evaluation of EUS in Preventing Rebleeding After Endoscopic Cyanoacrylate Injection for Gastric VaricesNCT05515861 · 2022-09-01
UNKNOWN
Effect of Low Tidal Ventilation on Intraoperative Bleeding in Laparoscopic Major HepatectomyNCT05490147 · 2022-08-08
UNKNOWN
Impact of Fentanyl Analgesia on the Accuracy of HVPG Measurements in Patients With Portal HypertensionNCT04724148 · 2022-01-01
UNKNOWN
Impact of Weight Loss in Cirrhosis With Obesity and MAFLDNCT05104541 · 2021-11-10
UNKNOWN
Comparing a Direct Versus an Indirect Approach to Measuring the Portalsytemic Pressure GradientsNCT04987034 · 2021-07-27
COMPLETED
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)NCT04283994 · 2021-07-26
COMPLETED
The Timing of Emergency Endoscopy for Esophagogastric Variceal Bleeding in CirrhosisNCT04932200 · 2021-06-15
UNKNOWN
Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)NCT04863703 · 2021-05-07
ACTIVE_NOT_RECRUITING
Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient MeasurementsNCT04668664 · 2021-04-05
COMPLETED
Safety and Tolerability Study of OP-724 in Liver Cirrhosis Patients by HIV/HCV with Hemophilia.NCT04688034 · 2021-03-15
COMPLETED
Extension Study of Carvedilol RCT StudyNCT05021406 · 2021-01-08
UNKNOWN
Accuracy of Magnetically Maneuvered Capsule Endoscopy for Detection of EGV in Patients With CirrhosisNCT03748563 · 2021-01-07
COMPLETED
Endoscopic Ruler for the Assessment of Variceal Bleeding Risks (CHESS2005)NCT04639323 · 2020-12-23
UNKNOWN
Characterization and Pathogenesis of ACLFNCT04975490 · 2020-12-01
UNKNOWN
Proton Pump Inhibitors in Cirrhotic PatientsNCT06384443 · 2020-10-01
COMPLETED
Efficacy and Safety of EUS-Guided Therapy Versus BRTO for Gastric Varices With ShuntNCT04828369 · 2020-10-01
COMPLETED

Common interventions

PlaceboDRUG10propranololDRUG4CarvedilolDRUG3SimvastatinDRUG3TIPSPROCEDURE3Carvedilol 12.5 mgDRUG2EHR-based Clinician JumpstartBEHAVIORAL2FoscenvivintDRUG2RifaximinDRUG2TerlipressinDRUG2Transjugular Intrahepatic Portosystemic Shunt (TIPS)PROCEDURE2AbstentionBEHAVIORAL1ARFI measurementDEVICE1Autologous bone marrow stem cells infusion （ABMSCi） plus abdominal portal hypertension surgeryPROCEDURE1AvenciguatDRUG1balloon-occluded retrograde transvenous obliterationPROCEDURE1BNP, SAAG, ascites total protein, echocardiographyPROCEDURE1BulevirtideDRUG1Carvedilol 6.25 mgDRUG1Coil-assisted Small-diameter Stent Shunt reductionPROCEDURE1conivaptanDRUG1conventional tidal volume (tidal volume [ml]= ideal body weight [kg]* 10~12) groupPROCEDURE1Diagnostic Test: Transient elastography (TE) and 2D-shear wave elastography (2D-SWE)DIAGNOSTIC_TEST1DigoxinDRUG1Distal Splenorenal ShuntPROCEDURE1

Trial status mix

COMPLETED41
UNKNOWN41
RECRUITING17
NOT_YET_RECRUITING10
TERMINATED7
ACTIVE_NOT_RECRUITING3
ENROLLING_BY_INVITATION1
WITHDRAWN1

Phase mix

NA34
PHASE215
PHASE312
PHASE412
PHASE12

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.