Condition

Acute Exacerbation of COPD

ClinicalTrials.gov condition label

Clinical trials27
Recruiting3
Common interventions25
Lead sponsors shown15

Clinical trials

27 shown
Controlled Versus Standard Oxygen Therapy in ICU Patients With Acute Exacerbation of COPDNCT07842510 · 2026-01-01
RECRUITING
High Flow Nasal Oxygen for Exacerbation COPDNCT06084117 · 2024-05-14
RECRUITING
Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter TrialNCT05280132 · 2022-12-08
RECRUITING
Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory SupportNCT07751003 · 2027-08-01
NOT_YET_RECRUITING
Evaluating Customized Antibiotic Duration (CDA) Strategy in Acute Exacerbations of COPDNCT07708337 · 2026-10-26
NOT_YET_RECRUITING
The Impact of Indoor Environmental Quality on Symptoms in Patients With Chronic Obstructive Pulmonary DiseaseNCT07799896 · 2026-10-01
NOT_YET_RECRUITING
Inhaler Trainer Efficacy StudyNCT06461403 · 2025-10-09
COMPLETED
Survey on NIV Settings in the Intensive Care Unit for Acute Exacerbation of COPDNCT06888180 · 2025-09-01
NOT_YET_RECRUITING
Remote Monitoring of COPD Patients Experiencing an Acute Exacerbation Through Health Evaluations Using Wearable Mobile TechnologyNCT06890767 · 2025-03-01
ACTIVE_NOT_RECRUITING
Randomized Controlled Study of Programmed Weaning From NIV for AECOPDNCT06014034 · 2023-05-12
ACTIVE_NOT_RECRUITING
Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil LevelsNCT05059873 · 2023-03-05
TERMINATED
Effect of NMES on Quadriceps Muscle Strength and Endurance in Patients With COPDNCT05539547 · 2022-10-01
UNKNOWN
Antibiotic Stewardship in AECOPD Through CRP-Guided ManagementNCT05286918 · 2022-09-01
UNKNOWN
Effects of Chair-Based Exercise Training on Exercise Capacity in Patients With Acute Exacerbation of COPDNCT05563493 · 2022-08-20
COMPLETED
Functional Strength Training and Neuromuscular Electrical Stimulation in Severe Acute Exacerbations of COPDNCT05480566 · 2022-06-01
TERMINATED
Social Media-based Bundle Care of AECOPD Patients.NCT05209607 · 2022-02-01
UNKNOWN
Prediction of Exacerbations and Management of COPD Patients With SAH Based on Millimeter Wave Radar MonitoringNCT05019911 · 2021-10-01
UNKNOWN
High VS Low Flow Nasal O2 for Acute Hypercapnic Respiratory FailureNCT04640948 · 2021-06-13
UNKNOWN
Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseNCT04843696 · 2021-04-08
UNKNOWN
ecco2R to facilitatE earLy libEration From mechanicAl Ventilation inpatientS With Copd Acute ExacerbationNCT04147104 · 2021-02-01
UNKNOWN
Effect of Blood Flow Restriction Resistance Exercises in COPDAE In-patient RehabilitationNCT04448236 · 2020-06-10
COMPLETED
Copd Exacerbation and Pulmonary Hypertension TrialNCT04538976 · 2020-02-01
COMPLETED
Non Invasive Ventilation With NAVA vs ASV for AECOPDNCT04414891 · 2019-12-01
COMPLETED
Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory DiseasesNCT04098094 · 2019-09-19
UNKNOWN
Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPDNCT03255057 · 2018-02-18
TERMINATED
Are Comorbidities Related to Frequent Severe Exacerbations of AECOPDNCT05504993 · 2018-01-01
COMPLETED
Patient Factors Associated With Prescription of Antibiotics for Inappropriate Indication in Patients With AECOPDNCT03077152 · 2017-01-01
COMPLETED

Common interventions

CAT QuestionnaireOTHER2Invasive mechanical ventilationDEVICE2Wearable mobile deviceDEVICE214-day antibiotic courseDRUG17-day antibiotic courseDRUG1Blood flow restriction resistance exerciseDEVICE1breathing training, and an educational program (relaxation techniques and a home pacing walking exercise)BEHAVIORAL1Control group, Breathing exerciseOTHER1Controlled oxygen therapyOTHER1cuirass ventilator (cuirass diameter 21 cm or 34 cm, Dima Italia Srl.,Bologna, Italy)DEVICE1Daily medical treatment (e.g., oxygen, medrol, duovent, azitromycine)DRUG1DHRQ QuestionnaireOTHER1eHLQ QuestionnaireOTHER1Frequency of AECOPDOTHER1Functional strength trainingOTHER1Hemolung Respiratory Assist SystemDEVICE1HFNOOTHER1High flow nasal therapyDEVICE1Housing QuestionnaireOTHER1Indoor environmental quality sensorDEVICE1Inhaler Trainer SystemDEVICE1Inhaler Use InstructionOTHER1Initial Inhaler Use AssessmentOTHER1KSS QuestionnaireOTHER1Low flow ECCO2RDEVICE1

Leading sponsors

Peking University Third Hospital2Alung Technologies1Ankara University1Assistance Publique - Hôpitaux de Paris1Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil1Beijing Chao Yang Hospital1Belfast Health and Social Care Trust1Capital Development Authority (CDA)1Capital Medical University1Chang Gung Memorial Hospital1Chronic Obstructive Pulmonary Disease Trial Network, Denmark1David Ruttens1Franciscus Gasthuis1Hasselt University1Hôpital Universitaire Taher Sfar1

Trial status mix

UNKNOWN8
COMPLETED7
NOT_YET_RECRUITING4
RECRUITING3
TERMINATED3
ACTIVE_NOT_RECRUITING2

Phase mix

NA18
PHASE43
EARLY_PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.