Condition

Amputation

ClinicalTrials.gov condition label

Clinical trials39

Recruiting3

Common interventions25

Lead sponsors shown15

Clinical trials

39 shown

MultiSENSory Stimulation to TArgeT Sensory Loss and ChronIc Pain in NeurOpathic PatieNtsNCT05483816 · 2022-06-30

Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic ClaudicationNCT04635436 · 2020-02-05

Additional Hyperbaric Oxygen After Lower Extremity AmputationNCT03594344 · 2018-07-04

TOE Study: Treatment and Gait Analysis fOllowing an Excised Lesser ToeNCT07441772 · 2026-04-01

NOT_YET_RECRUITING

Turkish Validation and Reliability of the John Hopkins In-Room Independence ScaleNCT07250243 · 2025-09-01

Ultrasonic Enhancement Delivery of Phosphodiesterase Inhibitors Nanoparticles for Diabetic Management of the FootNCT07690566 · 2025-09-01

Thermoregulation in Individuals With a Leg AmputationNCT06458426 · 2024-05-07

ENROLLING_BY_INVITATION

Deploying Digital Prosthetic Interface Technology and Exercise in Dysvascular AmputeesNCT05656924 · 2023-12-20

ACTIVE_NOT_RECRUITING

Toe Amputations in Patients With DiabetesNCT05855980 · 2023-05-22

Crossing the Divide: Piloting Integrated Care to Reduce Amputations Among Rural Patients With Diabetic Foot UlcersNCT05203471 · 2023-02-16

MetaMet: Bone Cutter Versus Bone Saw for Ray AmputationNCT05804565 · 2023-01-01

Comparison of Joint Position Sense in Diabetic and Traumatic Transtibial AmputeesNCT05542901 · 2022-09-13

Diabetic Foot Care and Limb Preservation Pathway: Developmental Evaluation StudyNCT05446337 · 2022-07-15

Effectiveness of the Autologous Adipose Tissue Harvested With SEFFICARE Method for Treatment of DFU Minor AmputationNCT05072353 · 2021-12-01

The Effect of Negative Pressure Wound Therapy on Wound Healing in Major Amputations of the Lower LimbNCT04618406 · 2021-11-01

Does Increasing Oxygen Nurture Your Symptomatic Ischemic Ulcer Sufficiently?NCT05804097 · 2021-10-08

ACTIVE_NOT_RECRUITING

Predictors of Foot Amputation in Diabetic Foot UlcersNCT05551988 · 2021-06-01

The PERCEIVE StudyNCT04903756 · 2020-10-01

Pattern and Type of Amputation and Mortality Rate Associated With Diabetic Foot in Jeddah, Saudi Arabia: A Retrospective Cohort StudyNCT05123157 · 2020-09-01

Kerecis Omega3 Wound Plus SOC vs. SOC Alone in Treating Severe Diabetic Foot Ulcers and Forefoot AmputationsNCT04257370 · 2020-07-09

Mechanical Determinants of Upper Limbs Oscillation During GaitNCT05778474 · 2020-05-27

Telehealth Pain Self-Management for Employed AdultsNCT04248725 · 2020-03-02

Dysvascular Amputation Self-Management of HealthNCT04083456 · 2019-11-01

Motor Learning in Individuals With Lower Limb Loss and Chronic DiabetesNCT03989063 · 2019-10-01

Study of the Value of Using a Honey Dressing Compared to the Use of a Standard Dressing on the Toe Amputation Wound in the Diabetic PatientNCT03934281 · 2018-06-27

A Wheelchair Propulsion Training ProgramNCT04009187 · 2018-03-27

Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in DiabeticsNCT03012529 · 2018-01-22

Digital Ankle Brachial Index (ABI) as a Screening Tool in Detecting Peripheral Arterial DiseaseNCT03161327 · 2017-07-15

Physical Activity Behavior Change for Older Adults After Dysvascular AmputationNCT02738086 · 2016-07-01

The Association of Cardiac Valve Calcification and 1-year Mortality After Lower-extremity Amputation in Diabetic PatientsNCT06079008 · 2016-06-01

Study to Determine if Different Prosthetic Sockets Effect How Much Oxygen is in the Tissue of Lower Limb Amputees While They Are WalkingNCT00985842 · 2009-11-01

Telephone Intervention for Pain Study (TIPS)NCT00663663 · 2009-09-01

Pathology of Skin, Nerve and Vasculature in the Amputated Limb of DiabetesNCT00840164 · 2009-02-01

A Randomized Exercise Trial for Wheelchair UsersNCT00866112 · 2008-05-01

Use of Subtle Vibration to Improve Walking Ability by Lower Limb AmputeesNCT00985881 · 2007-04-01

Penetration of Ertapenem Into BoneNCT00392028 · 2006-11-01

Vacuum Suspension: Effects on Tissue Oxygenation, Activity and FitNCT00117793 · 2005-08-01

Shear and Pressure Reducing Insoles for the Diabetic FootNCT00499356 · 2002-05-01

Herbal Preparation Used as Adjuvant Therapy on Diabetic UlcersNCT00393510 · 2000-11-01

Common interventions

30-minute education sessionBEHAVIORAL1 ABI using QuantaFlo™DEVICE1 Attention ControlOTHER1 Bone CutterPROCEDURE1 Bone SawPROCEDURE1 calcified cardiac valveOTHER1 Conventional prosthetic socket (current clinical practice)DEVICE1 Custom prosthetic socket with mechanical vibrators (stochastic resonance)DEVICE1 digital prosthetic interface technologyDEVICE1 E-TIPSBEHAVIORAL1 Educational session to promote physical activityOTHER1 ertapenemDRUG1 GlideSoft®DEVICE1 HAS recommendation dressingDEVICE1 Healthy subjectsOTHER1 Honey dressing Melectis GDEVICE1 Hyperbaric oxygenDRUG1 Hyperbaric oxygen therapyPROCEDURE1 In-person wheelchair propulsion training programBEHAVIORAL1 In-room independence assessmentOTHER1 Instructions to perform a motor task (external vs. internal focus instructions)BEHAVIORAL1 integrated care modelOTHER1 Joint Position Sense AnalysisDIAGNOSTIC_TEST1 Kerecis™ Omega3 WoundDEVICE1 Minimal contactOTHER1

Leading sponsors

VA Office of Research and Development4 Istituto Auxologico Italiano2 University of Washington2 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)1 Aneurin Bevan University Health Board1 Azienda Ospedaliero-Universitaria di Modena1 Bolan Medical Complex Hospital Quetta Pakistan1 Centre Hospitalier Metropole Savoie1 Chinese University of Hong Kong1 Deraya University1 Diabetica Solutions Inc.1 ETH Zurich1 HaEmek Medical Center, Israel1 Kerecis Ltd.1 King Abdulaziz University1

Trial status mix

COMPLETED25

UNKNOWN6

RECRUITING3

ACTIVE_NOT_RECRUITING2

ENROLLING_BY_INVITATION1

NOT_YET_RECRUITING1

WITHDRAWN1

Phase mix

NA27

PHASE22

PHASE42

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.