Condition

Chronic Bronchitis

ClinicalTrials.gov condition label

Clinical trials79
Recruiting3
Common interventions25
Lead sponsors shown15

Clinical trials

60 shown
Clinical Study of the Pulsed Electric Field Ablation System in Chronic Obstructive Pulmonary DiseaseNCT07068438 · 2025-09-01
RECRUITING
COPD Patient-Powered Research NetworkNCT02803242 · 2014-08-01
RECRUITING
Emphysema Research Registry and Biosample RepositoryNCT00307281 · 2000-08-01
RECRUITING
Repeat Treatment With Metered Cryospray in Patients With Chronic Obstructive Pulmonary Disease With Chronic BronchitisNCT07468617 · 2027-01-02
NOT_YET_RECRUITING
Pulmonary Deposition of Ultrasound Rock Salt Aerosol Inhalation TherapyNCT06891274 · 2025-03-31
NOT_YET_RECRUITING
A Clinical Evaluation of the RheOx Bronchial Rheoplasty SystemNCT05641207 · 2023-05-18
COMPLETED
Feasibility Study of the Pulsed Electric Field Ablation System in Treating Chronic BronchitisNCT05771129 · 2023-03-10
UNKNOWN
Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILENCT05649046 · 2023-01-23
UNKNOWN
Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke CigarettesNCT05610514 · 2022-04-28
COMPLETED
Evaluation of Immunological, Microbiological and Metabolomic Profiles in COPDNCT06826560 · 2022-03-01
COMPLETED
A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in ChinaNCT05337163 · 2022-02-25
COMPLETED
Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in Elderly People With Chronic Bronchitis and COPDNCT05104216 · 2021-12-01
UNKNOWN
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Elderly People With Chronic Bronchitis and COPDNCT05075083 · 2021-10-08
UNKNOWN
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Patients Aged ≥60 Years With Chronic Bronchitis and COPDNCT05075057 · 2021-10-08
UNKNOWN
Effect of Zhuli Capsule on Phlegm-heat Syndrome (Tan-re Zheng)NCT04834531 · 2021-07-01
UNKNOWN
Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic BronchitisNCT04677465 · 2021-04-07
UNKNOWN
A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)NCT04441788 · 2020-12-22
TERMINATED
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic BronchitisNCT04631016 · 2020-12-14
COMPLETED
RejuvenAir® System Trial for COPD With Chronic BronchitisNCT03893370 · 2020-07-09
UNKNOWN
Metered Cryospray for the Treatment of Patients With Chronic Obstructive Pulmonary Disease With Chronic BronchitisNCT03892694 · 2020-02-14
COMPLETED
Roflumilast or Azithromycin to Prevent COPD Exacerbations TrialNCT04069312 · 2020-02-11
COMPLETED
RheOx Registry Study in EuropeNCT04182841 · 2020-01-09
UNKNOWN
Mortality and Symptom Burden Post Hospitalisation With COPDNCT03657121 · 2019-01-16
COMPLETED
Gala Early Feasibility Study of RheOxNCT03631472 · 2018-07-06
UNKNOWN
Melodica Orchestra for Dyspnea: Safety and Feasibility PilotNCT03653104 · 2018-06-12
WITHDRAWN
Gala Treatment for Chronic Bronchitis in CanadaNCT03385616 · 2017-08-24
COMPLETED
Crossover Blinded Trial of Cell Therapy Versus Placebo in COPDNCT03228121 · 2017-04-24
WITHDRAWN
The Topic Trial - Study to Determine the Safety and Efficacy of IvacaftorNCT03085485 · 2017-03-16
COMPLETED
Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPDNCT03010592 · 2017-02-06
UNKNOWN
BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioImage StudyNCT03049202 · 2017-02-01
ACTIVE_NOT_RECRUITING
The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD CohortNCT02838108 · 2016-10-01
TERMINATED
Activity Monitor Use in COPD Patients Undergoing RehabilitationNCT02895152 · 2016-08-01
COMPLETED
Novel Therapies for Muco-Obstructive Lung Diseases: Testing the Transnasal Pulmonary Delivery Device in COPD/CB SubjectsNCT02341183 · 2016-05-01
WITHDRAWN
Patient-Centred Innovations for Persons With Multimorbidity - QuebecNCT02789800 · 2016-04-22
COMPLETED
Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic BronchitisNCT02416102 · 2016-03-31
TERMINATED
Patient-Centred Innovations for Persons With Multimorbidity - OntarioNCT02742597 · 2016-01-12
COMPLETED
The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPDNCT02099799 · 2015-11-17
COMPLETED
A Comparison Study of Two Respiratory Physical Therapy Methods and Standard Medical Treatment for Treating COPD Patients During Acute ExacerbationNCT02140892 · 2014-07-01
UNKNOWN
Evaluation of the Safety of the Medical Device Simeox®NCT02061852 · 2014-07-01
TERMINATED
Mindfulness-based Cognitive Therapy for Chronic Obstructive Pulmonary DiseaseNCT02042976 · 2014-02-01
COMPLETED
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole CathetersNCT01828788 · 2013-04-27
COMPLETED
The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic BronchitisNCT03073798 · 2013-03-18
COMPLETED
Sustained Effects of Hypertonic Saline on Mucociliary Clearance in Subjects With Chronic BronchitisNCT01792271 · 2013-02-01
COMPLETED
N-Acetylcysteine for Patients With COPD and Chronic BronchitisNCT01739790 · 2013-01-01
TERMINATED
N-Acetylcysteine for Patients With COPD and ChronicBronchitisNCT01599884 · 2012-06-01
UNKNOWN
Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed TomographyNCT01361984 · 2011-06-01
UNKNOWN
A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI)NCT01302587 · 2011-03-01
COMPLETED
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) PhenotypeNCT01431625 · 2011-01-01
UNKNOWN
Study of COPD Subgroups and BiomarkersNCT01969344 · 2010-11-01
ACTIVE_NOT_RECRUITING
Epidemiology of Chronic Bronchitis in Patients With Chronic Obstructive Pulmonary Disease (COPD)NCT02128529 · 2010-10-01
COMPLETED
The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive CoughNCT01071161 · 2009-09-01
COMPLETED
The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and DiseaseNCT00974064 · 2009-08-01
COMPLETED
CryoSpray Ablation(tm)Thoracic Patient RegistryNCT00785239 · 2009-04-01
WITHDRAWN
Efficacy of Losartan in Preventing Progression of COPDNCT00720226 · 2008-07-01
COMPLETED
PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)NCT00683722 · 2008-03-20
COMPLETED
Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)NCT00633776 · 2008-03-01
WITHDRAWN
Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic BronchitisNCT00656747 · 2008-03-01
COMPLETED
The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD)NCT00870896 · 2008-02-01
COMPLETED
Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease PatientsNCT00680056 · 2007-11-01
COMPLETED
Pulmonary Function Changes in 10 Pack Year Smokers With Chronic BronchitisNCT00454675 · 2007-03-01
COMPLETED

Common interventions

placeboDRUG10Inactivated COVID-19 vaccineBIOLOGICAL3SalmeterolDRUG3AzithromycinDRUG2N-acetylcysteineDRUG2RejuvenAir SystemDEVICE2RheOxDEVICE2RoflumilastDRUG2Sham ProcedureDEVICE27% hypertonic salineOTHER17% hypertonic saline (510K approved as a device)DEVICE1AlbuterolDRUG1Amoxicillin clavulanic acidDRUG1arformoterolDRUG1arformoterol tartrate inhalation solutionDRUG1Audit and FeedbackBEHAVIORAL1Avelox (Moxifloxacin, BAY12-8039)DRUG1azithromycin and fluticasoneDRUG1BLOOD SAMPLEBIOLOGICAL1chest CT or pathological examinationPROCEDURE1Coached exercise persistence interventionBEHAVIORAL1Combined Training (endurance and strength exercises)OTHER1Diagnostic Test: Sputum DNA methylation analysisDIAGNOSTIC_TEST1DIMAC02BEHAVIORAL1E-CigaretteOTHER1

Trial status mix

COMPLETED43
UNKNOWN15
TERMINATED7
WITHDRAWN6
ACTIVE_NOT_RECRUITING3
RECRUITING3
NOT_YET_RECRUITING2

Phase mix

NA28
PHASE414
PHASE210
PHASE34
PHASE12
EARLY_PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.