Condition
Mesothelioma, Malignant
ClinicalTrials.gov condition label
Clinical trials
29 shownPartial Pleurectomy (Surgery) for Unresectable Pleural MesotheliomaNCT07126509 · 2025-12-02
RECRUITINGFirst Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural MesotheliomaNCT05188859 · 2024-09-01
RECRUITINGSW-682 in Advanced Solid TumorsNCT06251310 · 2024-07-31
RECRUITINGA Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionNCT06051695 · 2024-04-03
RECRUITINGA Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal MesotheliomaNCT06057935 · 2023-09-21
RECRUITINGHTL0039732 in Participants With Advanced Solid TumoursNCT05944237 · 2023-08-02
RECRUITINGFirst Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.NCT06946498 · 2023-05-23
RECRUITINGSynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or MesotheliomaNCT05568680 · 2023-03-30
RECRUITINGSolid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingNCT04981119 · 2021-10-29
RECRUITINGA Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and LymphomasNCT04104776 · 2019-09-18
RECRUITINGNM32-2668 in Adult Patients With Selected Advanced Solid TumorsNCT06299163 · 2024-05-01
TERMINATEDClinical Study to Evaluate Safety and Dosing of CA9hu-1 in Patients With Advanced Solid TumoursNCT05698238 · 2024-01-01
NOT_YET_RECRUITINGTreatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin AdministrationNCT06281860 · 2023-11-24
UNKNOWNImmunological Variables Associated to ICI Toxicity in Cancer PatientsNCT05429866 · 2022-09-01
UNKNOWNNiraparib Efficacy in Patient With Unresectable MesotheliomaNCT05455424 · 2022-07-11
COMPLETEDA Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing CancerNCT05451849 · 2022-06-21
TERMINATED......SMARTEST Trial......NCT05380713 · 2022-05-03
COMPLETEDMolecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural MesotheliomaNCT04823741 · 2022-02-11
UNKNOWNA Study to Evaluate Nivolumab in Combination With Ipilimumab Versus Pemetrexed With Cisplatin or Carboplatin for Unresectable Pleural Mesothelioma in Chinese ParticipantsNCT05136677 · 2022-01-25
COMPLETEDA Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)NCT05324436 · 2022-01-08
COMPLETEDPembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients with PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior TherapiesNCT03546426 · 2019-12-12
ACTIVE_NOT_RECRUITINGPhase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing CancerNCT03907852 · 2019-04-15
ACTIVE_NOT_RECRUITINGMesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant MesotheliomaNCT03654833 · 2019-01-28
COMPLETEDPhase II Nivolumab and Ramucirumab for Patients With Previously-Treated MesotheliomaNCT03502746 · 2018-06-26
TERMINATEDCombination of Immunotherapy and Hyperthermia in Advanced Malignant MesotheliomaNCT03393858 · 2017-12-01
TERMINATEDStudy of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM)NCT02357147 · 2015-11-03
TERMINATEDCombination of Gemcitabine and Imatinib Mesylate in Pemetrexed-pretreated Patients With Pleural MesotheliomaNCT02303899 · 2014-11-01
COMPLETED11C-Methionine PET/CT Imaging in Patients Affected by Malignant Pleural Mesothelioma (MPM)NCT02519049 · 2014-09-01
COMPLETEDMalignant Mesothelioma - Can we Improve Quality of LifeNCT03068117 · 2014-04-03
COMPLETEDCommon interventions
CisplatinDRUG3cyclophosphamideDRUG3PemetrexedDRUG3CarboplatinDRUG2FludarabineDRUG2NivolumabDRUG2A2B543BIOLOGICAL1A2B694BIOLOGICAL1AbemaciclibDRUG1Active Symptom ControlOTHER1AmatuximabDRUG1Anti-PD-1 antibodyDRUG1ApheresisOTHER1Atezolizumab & BevacizumabDRUG1Autologous dendritic cellsBIOLOGICAL1CA9hu-1DRUG1Checkpoint Blockade, ImmuneDRUG1Cisplatine Teva®DRUG1Combination TherapyDRUG1DC-CIK ImmunotherapyBIOLOGICAL1Dostarlimab and NiraparibDRUG1DurvalumabDRUG1EnzalutamideDRUG1gavo-celBIOLOGICAL1GemcitabineDRUG1
Leading sponsors
A2 Biotherapeutics Inc.2Bristol-Myers Squibb2Istituto Clinico Humanitas2TCR2 Therapeutics2Arkadiusz Z. Dudek, MD1Cancer Institute and Hospital, Chinese Academy of Medical Sciences1Cancer Research UK1Capital Medical University1Dr Jean Yannis PERENTES1Hospices Civils de Lyon1Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS1Jules Bordet Institute1Mabpro, a.s.1Memorial Sloan Kettering Cancer Center1Morphotek1
Trial status mix
RECRUITING10
COMPLETED8
TERMINATED5
UNKNOWN3
ACTIVE_NOT_RECRUITING2
NOT_YET_RECRUITING1
Phase mix
PHASE216
PHASE112
NA3
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.