Condition
Esophageal Squamous Cell Carcinoma (ESCC)
ClinicalTrials.gov condition label
Clinical trials
7 shown177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid TumorsNCT07189871 · 2026-02-23
RECRUITINGA First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid TumorsNCT07085091 · 2025-08-18
RECRUITINGA Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected MalignanciesNCT05473156 · 2023-07-24
RECRUITINGPredictive Biomarkers for PD-1 Inhibitor Response in Squamous Cell CarcinomaNCT07147361 · 2025-09-12
ACTIVE_NOT_RECRUITINGA Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A)NCT05342636 · 2022-07-27
COMPLETEDStudy of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)NCT04210115 · 2020-02-28
COMPLETEDA Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid TumorsNCT03708328 · 2018-10-15
COMPLETEDCommon interventions
PembrolizumabBIOLOGICAL2177Lu-BetaBartDRUG15-FUDRUG1ALX2004DRUG1AP203DRUG1BetaBart + unlabeled BetaBartDRUG1cisplatinDRUG1Coformulation favezelimab/pembrolizumabBIOLOGICAL1IrinotecanDRUG1LenvatinibDRUG1leucovorinDRUG1levoleucovorinDRUG1LomvastomigDRUG1MK-4830BIOLOGICAL1oxaliplatinDRUG1PaclitaxelDRUG1placeboDRUG1radiotherapyRADIATION1
Leading sponsors
Trial status mix
COMPLETED3
RECRUITING3
ACTIVE_NOT_RECRUITING1
Phase mix
PHASE15
PHASE23
PHASE31
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.