Condition

COPD Exacerbation

ClinicalTrials.gov condition label

Clinical trials183

Recruiting15

Common interventions25

Lead sponsors shown15

Clinical trials

60 shown

Early Detection of COPD Exacerbations Using Home Monitoring DeviceNCT07554352 · 2026-08-05

High-intensity Resistance Training in Post-exacerbation COPDNCT07302425 · 2025-10-30

Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary DiseaseNCT05703919 · 2025-06-02

Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary DiseaseNCT06347536 · 2025-01-30

Role of Oral Care in Prevention of Nosocomial Pneumonia Among COPD PatientsNCT06691399 · 2024-10-01

Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS)NCT05958563 · 2024-01-09

Predicting Adverse Outcomes Using Machine Learning of COPD Patients in Hong KongNCT05825014 · 2023-08-29

DUET Versus Standard Interface for Hypercapnic COPD PatientsNCT05829083 · 2023-07-18

Non-contact Proactive Remote Monitoring of COPD ExacerbationsNCT05598983 · 2023-05-15

Effect of Home Based Pulmonary Rehabilitation on Exacerbation and Hospital Admission in Severe COPDNCT05738720 · 2023-02-01

Patients With Severe Acute Exacerbation of COPD Ans Admitted in ICU Register.NCT06257329 · 2022-10-01

Multidisciplinary Management of Severe COPDNCT04860375 · 2021-09-22

Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric SurgeryNCT04136717 · 2019-10-28

Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) PatientsNCT03890224 · 2019-07-04

Nasal High-Flow in COPDNCT03564236 · 2018-10-01

Combination of High-flow Nasal Oxygen (Optiflow) and Vibrating Membrane Nebuliser (Aerogen) in the Pre-hospital Setting - Before/After StudyNCT07791992 · 2026-10-01

Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)NCT07721922 · 2026-09-01

NOT_YET_RECRUITING

A Repeat Ascending Dosing Study of the Safety and Clinical Activity of R-3750 in Patients With Mild to Moderate COPDNCT07076290 · 2026-09-01

NOT_YET_RECRUITING

Emotional-distress-based Integrated Care Programme in Patients With an Acute Exacerbation of COPDNCT07351929 · 2026-01-12

ACTIVE_NOT_RECRUITING

The COPD CARE Study: Evaluating the Impact of a Virtual-First COPD Service on Major Cardiac and Respiratory EventsNCT06379529 · 2026-01-01

NOT_YET_RECRUITING

Study on Home Obstructive Respiratory ExacerbationsNCT06544928 · 2025-12-05

ENROLLING_BY_INVITATION

Telehealth Education Leveraging Electronic Transitions Of Care for COPD PatientsNCT05897125 · 2025-02-19

ENROLLING_BY_INVITATION

Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Patients with Chronic Obstructive Bronchopneumopathy.NCT06653933 · 2025-01-01

NOT_YET_RECRUITING

The Effect of Stress Ball on COPD Patients Receiving Noninvasive Mechanical Ventilation SupportNCT06461169 · 2024-06-15

Impulse Oscillometry in COPD ExacerbationNCT07185581 · 2024-03-01

Comfort of Patients Under Non Invasive Ventilation According to the MaskNCT06212180 · 2024-01-01

A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Adolescent and Adult Patients in an Emergency DepartmentNCT06156462 · 2024-01-01

Exacerbantes StudyNCT06147206 · 2023-12-31

Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseNCT06211920 · 2023-12-08

Ultrasonographic Evaluation of Diaphragm and Quadriceps in Chronic Obstructive Pulmonary Disease (COPD) PatientsNCT04509128 · 2023-12-01

PSV Versus ASV With Intellisync Mode for Delivery of NIV in AECOPDNCT06160687 · 2023-12-01

Ferroptosis in Patients With COPD COPD With/Without Risk of Cardiovascular Events. Pathophysiological Implications, Diagnostics and Prognoses. FerrEPOC Study.NCT06102993 · 2023-10-01

Physiological and Environmental Data in a Remote Setting to Predict Exacerbation Events in Patients With Chronic Obstructive Pulmonary DiseaseNCT06118632 · 2023-09-22

Telehealth and Onsite Maintenance Exercise in Chronic Lung DiseaseNCT06304207 · 2023-09-01

Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen FlowsNCT05819164 · 2023-05-25

Clinical Study for the Effectiveness of Roflumilast Treatment in COPD Greek Patients Based on Standard Clinical Practice.NCT05426915 · 2023-05-01

Exploring Clinical Predictors of COPD Exacerbation in a Community CohortNCT05762861 · 2023-04-01

The Addition of Inhaled Furosemide to Standard Treatment of COPD ExacerbationNCT05769738 · 2023-03-01

Multi-omics Studies of Host-microbiome Interaction in Chronic Obstructive Pulmonary Disease and BronchiectasisNCT05738044 · 2023-02-20

Effect of Noninvasive High Frequency Oscillatory Ventilation on Improving CO2 Clearance in COPD PatientsNCT05721833 · 2023-02-10

Early Extubation by ECCO2R Compared to IMV in Patients with Severe Acute Exacerbation of COPDNCT03584295 · 2023-02-07

Risk Stratifying COPD ExacerbationsNCT05852327 · 2023-02-01

Once Daily Long-Acting Muscarinic Antagonists Administered in the Evening for Prevention of Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization or Death from Any CauseNCT05563675 · 2023-01-27

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient OutcomesNCT05443321 · 2022-11-01

ENROLLING_BY_INVITATION

Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPDNCT05507242 · 2022-10-25

Study to Identify the Reduction of Exacerbations Resulting in Hospital Admission in Patients With COPD.NCT05440188 · 2022-10-01

Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPDNCT05865184 · 2022-09-28

Healthy At Home PilotNCT06000696 · 2022-09-09

Pulmonary Rehabilitation for COPD Patients: Can Performance Predict Exacerbation?NCT05492149 · 2022-09-01

Evaluation of the Efficacy of Different Nebulization TechniquesNCT05507060 · 2022-08-01

Effect of Cough Assist Device in COPD Patients Admitted to Respiratory Intensive Care Unit at Assiut University HospitalNCT05491408 · 2022-08-01

Markers of COPD ExacerbationsNCT05315674 · 2022-07-25

Performance of Novel Bed Side Scores as Predictors of Hospital Outcome in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Among Women; Cohort StudyNCT05370664 · 2022-07-01

Virtual Reality in COPD ExacerbationNCT05687396 · 2022-06-01

Cough Monitoring in COPDNCT07098793 · 2022-05-18

A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPDNCT04320342 · 2022-04-27

Clinical Feasibility of a Non-invasive Wearable Acoustic Device for Measuring Air Trapping in COPDNCT04450368 · 2022-03-01

Use of ΔIVC for Early Diagnosis of AHF in AECOPDNCT05327374 · 2022-03-01

Inhaled Amikacin in Preventing AECOPDNCT05213507 · 2022-03-01

Short-course Antibiotic Treatment in AECOPD: a Meta-analysis of Double-blind StudiesNCT05380375 · 2022-02-24

Common interventions

Leading sponsors

Assiut University6 University of Monastir5 China-Japan Friendship Hospital4 Laval University4 Universidad de Granada4 University of Tennessee Graduate School of Medicine3 AstraZeneca2 Bezmialem Vakif University2 Central Denmark Region2 Chronic Obstructive Pulmonary Disease Trial Network, Denmark2 Elpen Pharmaceutical Co. Inc.2 François Lellouche2 Groupe Hospitalier du Havre2 Guy's and St Thomas' NHS Foundation Trust2 Hospital Universitario Marqués de Valdecilla2

Trial status mix

COMPLETED81

UNKNOWN60

RECRUITING15

TERMINATED14

ACTIVE_NOT_RECRUITING4

NOT_YET_RECRUITING4

ENROLLING_BY_INVITATION3

WITHDRAWN2

Phase mix

NA83

PHASE414

PHASE311

PHASE24

PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.