Condition

Stage III Lung Cancer AJCC v8

ClinicalTrials.gov condition label

Clinical trials88
Recruiting22
Common interventions25
Lead sponsors shown15

Clinical trials

60 shown
SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung CancerNCT07322341 · 2026-10-01
RECRUITING
Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C MutationNCT07012031 · 2026-06-17
RECRUITING
Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT StudyNCT07405086 · 2026-06-08
RECRUITING
New York Better Breathing StudyNCT06869447 · 2026-04-20
RECRUITING
GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung CancerNCT07017829 · 2026-04-01
RECRUITING
Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent ImmunotherapyNCT06731270 · 2025-04-09
RECRUITING
Defactinib, Avutometinib and Nivolumab for the Treatment of Anti-PD1 Refractory LKB1-Mutant Advanced Non-Small Cell Lung CancerNCT06495125 · 2024-07-31
RECRUITING
Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation TherapyNCT06139627 · 2024-05-21
RECRUITING
Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung CancerNCT06249282 · 2024-04-24
RECRUITING
A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung CancerNCT06122064 · 2023-11-20
RECRUITING
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung CancerNCT05624996 · 2023-07-12
RECRUITING
CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid TumorsNCT05733000 · 2023-03-08
RECRUITING
The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung CancerNCT05502523 · 2022-08-31
RECRUITING
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung CancerNCT05098210 · 2022-06-09
RECRUITING
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid TumorsNCT05269381 · 2022-03-31
RECRUITING
Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung CancerNCT05136846 · 2021-12-06
RECRUITING
Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung TrialNCT04789681 · 2021-07-20
RECRUITING
Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 TherapyNCT04892953 · 2021-07-07
RECRUITING
Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized ChemoradiationNCT05010109 · 2021-07-05
RECRUITING
Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With CancerNCT03819296 · 2021-02-21
RECRUITING
Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their CaregiversNCT03948100 · 2018-12-20
RECRUITING
Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer TypesNCT06075524 · 2015-06-15
RECRUITING
Testing Repeat Radiation Therapy for Recurrent Non-small Cell Lung CancerNCT07835789 · 2026-12-18
NOT_YET_RECRUITING
Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO TrialNCT07576725 · 2026-12-01
NOT_YET_RECRUITING
CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung CancerNCT07543172 · 2026-10-15
NOT_YET_RECRUITING
Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell Lung CancerNCT06816979 · 2026-09-15
NOT_YET_RECRUITING
Durvalumab and Grid Therapy for Non-small Cell Lung Cancer in Progression During or After Treatment With PACIFIC RegimenNCT05443971 · 2024-01-08
TERMINATED
Pilot Trial of E Cigarettes in Pts Diagnosed With Cancer of the Head, Neck, and LungNCT05412875 · 2024-01-01
WITHDRAWN
The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint InhibitorsNCT05967533 · 2023-06-02
SUSPENDED
EMB-01 in Combination With Osimertinib in Patients With EGFR Mutant Lung CancerNCT05498389 · 2023-06-01
UNKNOWN
Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung CancerNCT05198830 · 2022-12-15
ACTIVE_NOT_RECRUITING
Subcutaneous Atezolizumab for the Treatment of Non-small Cell Lung CancerNCT05340309 · 2022-12-07
ACTIVE_NOT_RECRUITING
Remote Monitoring With Health-Coaching for Lifestyle Changes in Patients With Lung Cancer Related FatigueNCT05407038 · 2022-08-17
TERMINATED
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint InhibitorsNCT05334329 · 2022-07-20
ACTIVE_NOT_RECRUITING
Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)NCT05096663 · 2022-03-15
ACTIVE_NOT_RECRUITING
Minnelide and Osimertinib for the Treatment of Advanced EGFR Mutated Non-Small Cell Lung CancerNCT05166616 · 2022-03-07
ACTIVE_NOT_RECRUITING
Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung CancerNCT05017025 · 2022-02-17
COMPLETED
ADMIRAL Trial: Adaptive Mediastinal Radiation With Chemo-ImmunotherapyNCT04372927 · 2021-12-10
TERMINATED
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIVNCT04514484 · 2021-11-22
ACTIVE_NOT_RECRUITING
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic CancerNCT04514497 · 2021-10-20
ACTIVE_NOT_RECRUITING
Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial CarcinomaNCT04940299 · 2021-09-23
ACTIVE_NOT_RECRUITING
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial CancerNCT04491942 · 2021-08-25
ACTIVE_NOT_RECRUITING
Effects of Probiotics on the Gut Microbiome and Immune System in Operable Stage I-III Breast or Lung CancerNCT04857697 · 2021-07-01
COMPLETED
Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung CancerNCT04971187 · 2021-06-30
TERMINATED
Registrational Trial to Compare Effectiveness of Two Digital Software Medical Devices as Adjunctive Oncology TreatmentNCT04862195 · 2021-05-15
TERMINATED
Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted AntibodiesNCT04902040 · 2021-04-14
TERMINATED
Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung CancerNCT04705025 · 2021-04-08
TERMINATED
Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid MalignanciesNCT04785287 · 2021-03-29
TERMINATED
A Nurse-Led Intervention for Fear of Progression in Advanced CancerNCT04819997 · 2021-03-08
ACTIVE_NOT_RECRUITING
Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME StudyNCT05022394 · 2021-02-18
WITHDRAWN
Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung CancerNCT04751747 · 2021-02-11
ACTIVE_NOT_RECRUITING
NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung CancerNCT04505267 · 2021-02-10
ACTIVE_NOT_RECRUITING
BeWell360-CG Care Model: Health and Wellness Coaching to Support Caregivers of Patients Living With Advanced Lung CancersNCT05640765 · 2021-02-03
COMPLETED
Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine CarcinomasNCT04701307 · 2021-02-01
ACTIVE_NOT_RECRUITING
Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer PatientsNCT04310020 · 2021-01-13
ACTIVE_NOT_RECRUITING
National Cancer Institute "Cancer Moonshot Biobank"NCT04314401 · 2020-11-11
ACTIVE_NOT_RECRUITING
Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung CancerNCT04396535 · 2020-10-23
TERMINATED
Decision Aid for the Improvement of Decision-Making in Patients With Non-small Cell Lung CancerNCT04946279 · 2020-08-07
ACTIVE_NOT_RECRUITING
Family Caregivers in Underserved Populations Providing Complex Cancer CareNCT05213078 · 2020-07-15
COMPLETED
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal CancerNCT04428905 · 2020-07-11
ACTIVE_NOT_RECRUITING

Common interventions

Biospecimen CollectionPROCEDURE33Computed TomographyPROCEDURE24Questionnaire AdministrationOTHER24Magnetic Resonance ImagingPROCEDURE16Quality-of-Life AssessmentOTHER13NivolumabBIOLOGICAL12DurvalumabBIOLOGICAL10PembrolizumabBIOLOGICAL10CarboplatinDRUG9PemetrexedDRUG9Radiation TherapyRADIATION9CisplatinDRUG8Positron Emission TomographyPROCEDURE8Best PracticeOTHER6BiopsyPROCEDURE6PaclitaxelDRUG6AtezolizumabBIOLOGICAL5Biopsy ProcedurePROCEDURE5Educational InterventionOTHER5Electronic Health Record ReviewOTHER5EtoposideDRUG5OsimertinibDRUG4Survey AdministrationOTHER4CyclophosphamideDRUG3Echocardiography TestPROCEDURE3

Trial status mix

ACTIVE_NOT_RECRUITING31
RECRUITING22
COMPLETED15
TERMINATED11
NOT_YET_RECRUITING4
WITHDRAWN3
SUSPENDED1
UNKNOWN1

Phase mix

PHASE234
PHASE131
NA20
PHASE36
EARLY_PHASE12
PHASE41

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.