Condition

Aortic Valve Failure

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 5 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials5

Recruiting0

Common interventions7

Lead sponsors shown4

Clinical trials

5 shown

DurAVR™ THV EU-EFSNCT06510855 · 2025-01-21

ACTIVE_NOT_RECRUITING

NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR TrialNCT05666713 · 2023-02-21

COMPLETED

Portico and Navitor India Clinical TrialNCT05171712 · 2022-05-06

COMPLETED

Portico Valve-in-Valve Retrospective RegistryNCT05002088 · 2021-10-21

COMPLETED

PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on ApixabanNCT04142658 · 2020-05-01

TERMINATED

Common interventions

Transcatheter Aortic Valve ReplacementDEVICE2 Apixaban 2.5 MGDRUG1 Apixaban 5 MGDRUG1 DurAVR™ THV SystemDEVICE1 On-X Aortic Mechanical ValveDEVICE1 TELLTALE BASILICA procedureDEVICE1 WarfarinDRUG1

Mapped drugs appearing in these trials

Shared trial participation only; not evidence of efficacy or approval.

apixaban 2.5 MG1 apixaban 5 MG1 warfarin1

Leading sponsors

Abbott Medical Devices 2 Anteris Technologies Ltd. 1 Artivion Inc. 1 National Heart, Lung, and Blood Institute (NHLBI) 1

Trial status mix

COMPLETED3

ACTIVE_NOT_RECRUITING1

TERMINATED1

Phase mix

NA3

PHASE31

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.