Condition
Cardiogenic Shock
ClinicalTrials.gov condition label
How to interpret these research links
Connected source recordsThis is the original ClinicalTrials.gov condition label, found in 72 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.
Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.
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Clinical trials
60 shownRandomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic ShockNCT07583446 · 2026-09-09
RECRUITINGCOMPARE-VENT Feasibility Pilot StudyNCT07656259 · 2026-07-01
RECRUITINGProlonged Nasogastric Administration of Ketones in Decompensated Heart FailureNCT07527156 · 2026-04-04
RECRUITINGEmpagliflozin's Microcirculatory Effects in Cardiogenic Shock: an Ancillary Pilot Study of the EMPASHOCK TrialNCT07141355 · 2025-12-12
RECRUITINGMagenta Elevate™ Clinical Feasibility Study in Cardiogenic ShockNCT07293923 · 2025-11-05
RECRUITINGBEAT-SHOCK RegistryNCT07643610 · 2025-10-01
RECRUITINGClinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic ShockNCT07825363 · 2025-06-17
RECRUITINGMulticenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp SystemNCT06080074 · 2025-04-15
RECRUITINGEffect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock PatientsNCT06862700 · 2025-02-26
RECRUITINGEffect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function.NCT05879276 · 2024-12-16
RECRUITINGMultimodal Phenotyping In Patients Referred With Acute Cardiac faiLurENCT07515508 · 2024-08-07
RECRUITINGChanges in Skeletal Muscle Thickness in Patients With Acute Heart FailureNCT06253104 · 2024-02-19
RECRUITINGPulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEFNCT06078436 · 2024-01-01
RECRUITINGNaples Federico II Intensive Cardiac Care Unit Registry (Naples FED2-ICCU Registry)NCT06162247 · 2023-11-20
RECRUITINGCardiac Power Output in Cardiogenic Shock PatientsNCT05700617 · 2023-07-06
RECRUITINGEffect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic ShockNCT04020263 · 2023-07-03
RECRUITINGStudy of Patients Admitted to a Cardiac Intensive Care Unit With Acute CardioVascular DiseaseNCT06081205 · 2023-04-27
RECRUITINGRole of Candidate Proteins in Capillary Leakage During Acute Circulatory FailureNCT05586282 · 2023-03-20
RECRUITINGTemporary MCS With the iVAC 2L Transaortic Device in High-risk PCINCT07149714 · 2023-02-17
RECRUITINGPharmacological and Mechanical Support Approaches in the Management of Acute Heart Failure in the Regional Network Model for the Management of Cardiogenic ShockNCT06827314 · 2022-12-06
RECRUITINGPulmonary Artery Catheter in Cardiogenic Shock TrialNCT05485376 · 2022-08-23
RECRUITINGCytOSorb TreatMent Of Critically Ill PatientS RegistryNCT05146336 · 2022-06-22
RECRUITINGAssessment of ECMO in Acute Myocardial Infarction Cardiogenic ShockNCT04184635 · 2021-10-14
RECRUITINGHemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock TrialNCT04419480 · 2020-12-31
RECRUITINGCharacterisation of phenotYpes in aCute Heart faiLure patiEntsNCT07508891 · 2019-03-01
RECRUITINGCardiogenic Shock Working Group RegistryNCT04682483 · 2017-12-04
RECRUITINGChina Extracorporeal Life Support RegistryNCT04158479 · 2017-01-01
RECRUITINGCORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic ShockNCT07461961 · 2026-10-01
NOT_YET_RECRUITINGRoutine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic ShockNCT07762560 · 2026-10-01
NOT_YET_RECRUITINGINitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac RecoveryNCT06965504 · 2026-09-01
NOT_YET_RECRUITINGPrognostic Value Enhancement Of Sequential Organ Failure Assessment )SOFA( Score by Neutrophil-Lymphocyte Ratio and Red Cell Distribution Width in Cardiogenic Shock Patients.NCT07773597 · 2026-08-30
NOT_YET_RECRUITINGOxygen Delivery Index (ODIN) StudyNCT07601828 · 2026-05-01
NOT_YET_RECRUITINGRoutine Versus Provisional Distal Perfusion Catheter Placement in Patients Undergoing Mechanical Circulatory SupportNCT07482865 · 2026-05-01
NOT_YET_RECRUITINGThe Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in MartiniqueNCT07351435 · 2026-02-01
NOT_YET_RECRUITINGHemodynamic Evaluation of Left Atrial Pressure in Relationship to Pulmonary Capillary Wedge Pressure in Cardio Thoracic PatientsNCT07163052 · 2025-09-01
NOT_YET_RECRUITINGEffect of Early Empagliflozin Initiation in Cardiogenic Shock.NCT07450417 · 2025-03-10
ACTIVE_NOT_RECRUITINGREMAP ECMO - Beta Receptor Modulation TrialNCT06522594 · 2024-06-01
UNKNOWNClinical Effects of Intra-aortic Balloon Support in Early Acute Coronary Syndrome and Non-Acute Coronary Syndrome Related Cardiogenic ShockNCT06414187 · 2024-06-01
NOT_YET_RECRUITINGThe Usefulness of Myocardial Work IndeX in ExtraCorporeal Membrane Oxygenation PatientsNCT05838937 · 2024-06-01
UNKNOWNThe RECOVER IV TrialNCT05506449 · 2023-10-28
TERMINATEDUnloading in Heart Failure Cardiogenic ShockNCT05064202 · 2023-10-01
NOT_YET_RECRUITINGInfluence of Enteral Microbiome on Mortality of Patients With Cardiogenic ShockNCT06006754 · 2023-08-30
COMPLETEDIvabradine Effects in Cardiogenic Shock Requiring Inotropic SupportNCT05594342 · 2022-07-01
UNKNOWNREnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)NCT05788211 · 2022-01-01
COMPLETEDNIVIA-HemodynamicsNCT06330597 · 2021-07-17
UNKNOWNECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic ShockNCT05027529 · 2021-05-21
COMPLETEDFeasibility and Safety of Total Percutaneous Closure of Femoral Arterial Access Sites in the Veno-arterial ECMO PatientsNCT04689451 · 2021-02-01
UNKNOWNECLS Versus IMPELLA™ as Bridge to LVAD (ECI-BLAD)NCT04480151 · 2021-01-20
COMPLETEDInnovative Technologies for the Treatment of Pulmonary and Heart FailureNCT05090930 · 2021-01-01
UNKNOWNThe Safety and Efficacy of Istaroxime for Pre-Cardiogenic ShockNCT04325035 · 2020-09-28
COMPLETEDSURPASS Impella 5.5 StudyNCT05100836 · 2020-09-21
COMPLETEDPressure Volume LoopNCT04478188 · 2020-08-01
UNKNOWNStudy on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic ShockNCT04369573 · 2020-05-04
TERMINATEDComparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac OutputNCT04206865 · 2019-11-25
WITHDRAWNCardiogenic Shock Registry MannheimNCT05575856 · 2019-06-01
UNKNOWNLeft Ventricular Volume Index in the Adjustment of Initial Dose of Dobutamine in Heart Failure and Cardiogenic ShockNCT03727282 · 2019-01-02
UNKNOWNLevosimendan for Veno-arterial ECMO WeaningNCT04323709 · 2019-01-01
COMPLETEDVeno-arterial Extracorporeal Membrane Oxygenation Prior to Left Ventricular Assist Device Implantation.NCT03583970 · 2018-07-05
UNKNOWNUltrasound Study of the Diaphragm Evolution Under ECMONCT03736239 · 2018-06-15
COMPLETEDEfficacy and Safety on Heart Rate Control With Ivabradine on Cardiogenic ShockNCT03437369 · 2018-05-01
UNKNOWNCommon interventions
PlaceboDRUG4LevosimendanDRUG3Pulmonary artery catheterDEVICE3standard of careOTHER3CytoSorbDEVICE2ECMODEVICE2Impella 5.5DEVICE2istaroximeDRUG21:1 Randomization to receive milrinoneDRUG1Acute Mechanical Circulatory Support DevicesDEVICE1adjust dobutamine according to the attending physicianPROCEDURE1adjust dobutamine according to the ejection volume indexPROCEDURE1Admission in the Cardiac Intensive Care Unit (CICU)OTHER1BivalirudinDRUG1BodyMetrix Body Composition UltrasoundDIAGNOSTIC_TEST1Cardiohelp device (VA-ECMO)DEVICE1CardioMEMS implantation with routine ambulatory pulmonary artery pressure monitoring and medication optimizationDEVICE1Conventional hemodynamic monitoringPROCEDURE1CytoSorb (CytoSorbents Corp., USA) - an extracorporeal cytokine adsorberDEVICE1Data analysisOTHER1Data collectionOTHER1Distal perfusion catheter insertionPROCEDURE1DobutamineDRUG1DOBUTamine Injectable SolutionDRUG1Early intra-aortic balloon pump (IABP) implantationCOMBINATION_PRODUCT1
Leading sponsors
Central Hospital, Nancy, France
4
Abiomed Inc.
3
Erasmus Medical Center
3
Tufts Medical Center
3
Amsterdam UMC, location VUmc
2
Assistance Publique - Hôpitaux de Paris
2
Nanjing Medical University
2
University Hospital, Bordeaux
2
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
1
Association Pro-arte
1
Beijing Anzhen Hospital
1
Brigham and Women's Hospital
1
Cedars-Sinai Medical Center
1
Christian Schulze
1
Columbia University
1
Trial status mix
RECRUITING27
UNKNOWN17
COMPLETED12
NOT_YET_RECRUITING10
TERMINATED4
ACTIVE_NOT_RECRUITING1
WITHDRAWN1
Phase mix
NA20
PHASE26
PHASE46
PHASE35
EARLY_PHASE11
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.