Condition
Acute Decompensated Heart Failure
ClinicalTrials.gov condition label
Clinical trials
60 shownA Study Of Acute Decompensated Heart FailureNCT07572955 · 2026-08-26
RECRUITINGAdd-on Diuretics in Acute Decompensated Heart FailureNCT07372040 · 2026-02-01
RECRUITINGComparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart FailureNCT07199088 · 2025-10-11
RECRUITINGBEAT-SHOCK RegistryNCT07643610 · 2025-10-01
RECRUITINGFluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)NCT06898515 · 2025-07-14
RECRUITINGUsing an Intervention Adapted to the Health Literacy Level to Improve Adherence to Medical RecommendationsNCT03951467 · 2025-06-26
RECRUITINGClinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic ShockNCT07825363 · 2025-06-17
RECRUITINGVenous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart FailureNCT06714409 · 2024-09-16
RECRUITINGCombination Oral Acetazolamide and Intravenous Furosemide on Acute Decompensated Heart Failure OutcomesNCT06475105 · 2024-04-20
RECRUITINGReprieve System Pilot StudyNCT06272734 · 2024-01-23
RECRUITINGEACH-ADHF: Early Comprehensive Rehabilitation in Patients With ADHFNCT06161987 · 2023-12-01
RECRUITINGStudy of Patients Admitted to a Cardiac Intensive Care Unit With Acute CardioVascular DiseaseNCT06081205 · 2023-04-27
RECRUITINGSafety and Performance Evaluation of the Nephronyx System for the Treatment of Patients With ADHFNCT05759806 · 2022-12-19
RECRUITINGLow Level Tragus Stimulation in Acute Decompensated Heart FailureNCT02898181 · 2016-09-01
RECRUITINGCirculating Markers That Underlie the Transition From Compensated Hypertrophy to Heart FailureNCT00762008 · 2005-12-01
RECRUITINGTherapy Adjustment and IndividuaLized Response With Biomarker Observation in ReaL-world Heart FailureNCT07647848 · 2026-09-01
NOT_YET_RECRUITINGEarly Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart FailureNCT07018297 · 2026-08-01
NOT_YET_RECRUITINGPREcision meDICine in Treatment in CardioVascular DiseaseNCT07369141 · 2026-02-01
WITHDRAWNCardiac Perfusion and Metabolism With [11C] Acetate PET/CT is Associated With Hematopoietic System Activation in Acute Decompensated Heart Failure: An Imaging Sub-studyNCT03924102 · 2025-12-31
WITHDRAWNEffects of In-Hospital Cardiac Rehabilitation and Manual Lymphatic Drainage in Acute Decompensated Heart FailureNCT07095764 · 2025-08-12
COMPLETEDNaturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European RegistryNCT06401109 · 2025-02-01
UNKNOWNIC14 for Treatment of Acute Decompensated Heart FailureNCT06556810 · 2024-10-17
ACTIVE_NOT_RECRUITINGAcetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure PatientsNCT06535529 · 2024-08-24
UNKNOWNFeasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic ResistanceNCT06174623 · 2024-08-01
UNKNOWNDORAYA-HF OUS Assessment of the Doraya Catheter for the Treatment of ADHF Patients With Insufficient Response to DiureticsNCT05876078 · 2024-07-01
COMPLETEDEfficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume OverloadNCT06414759 · 2024-07-01
UNKNOWNCompression Therapy of the Lower Limbs in Patients With Decompensated Heart FailureNCT06418932 · 2024-05-27
COMPLETEDEU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System (FASTR-EU)NCT06362668 · 2024-05-17
COMPLETEDS-ADHF:Sarcopenia in Patients With ADHFNCT06298825 · 2024-04-01
UNKNOWNA Study to Assess Multidomain Endpoints of an ECG PatchNCT06243029 · 2024-01-08
COMPLETEDThe Association Between Visual Echocardiographic Scoring System and Clinical Outcomes in Patient With Acute Decompensated Heart FailureNCT06586008 · 2024-01-01
UNKNOWNMobile Education System to Improve Disease Knowledge, Self-efficacy and Quality of Life in Patients With Heart FailureNCT06161649 · 2023-11-21
UNKNOWNThe Hemodynamic Effects of SGLT2i in Acute Decompensated Heart FailureNCT05346653 · 2023-05-22
TERMINATEDPharmacokinetics of Bisoprolol and SGLT2i in Acutely Decompensated Heart FailureNCT06453577 · 2023-05-01
COMPLETEDAdherence to Medication in Patients With Acute Decompensated Heart FailureNCT06459115 · 2023-02-01
COMPLETEDInspiratory Muscle Training in Acute Decompensated Heart FailureNCT04834336 · 2023-01-15
UNKNOWNDORAYA-HF Early Feasibility StudyNCT05206422 · 2022-10-05
COMPLETEDChange in Stroke Volume Index After Diuresis for Patients With Decompensated Heart FailureNCT05240651 · 2022-08-30
SUSPENDEDFluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS)NCT05174312 · 2022-07-11
COMPLETEDShort-term Mortality Prediction by the SOFA Score in Acute Decompensated Heart FailureNCT06354426 · 2022-07-01
COMPLETEDThe STIM-ADHF StudyNCT05313438 · 2022-05-10
COMPLETEDEvaluation of Blood Volume Analysis- Guided Management of Decompensated Heart FailureNCT04855097 · 2022-05-01
COMPLETEDUse of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility StudyNCT05291884 · 2022-04-20
ACTIVE_NOT_RECRUITINGEmpagliflozin and Dapagliflozin in Patients Hospitalized for Acute Decompensated Heart FailureNCT05776043 · 2022-03-15
UNKNOWNReadily Available Urinary Sodium Analysis in Patients With Acute Decompensated Heart FailureNCT06278792 · 2022-03-07
COMPLETEDUse of ΔIVC for Early Diagnosis of AHF in AECOPDNCT05327374 · 2022-03-01
COMPLETEDDR REGISTRY: Prospective Observational Study of ADHF Patients With Insufficient Response to DiureticsNCT04877652 · 2021-11-17
COMPLETEDMotivational Enhancement - Acute Decompensated Heart Failure and OSANCT04752462 · 2021-05-13
COMPLETEDCardionomic STOP-ADHF StudyNCT04814134 · 2021-04-12
COMPLETEDAsses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart FailureNCT06003972 · 2021-01-04
COMPLETEDStudy of the Safety of BMS-986259 in Participants With Post-Acute Decompensated Heart FailureNCT04318093 · 2020-11-06
COMPLETEDSURPASS Impella 5.5 StudyNCT05100836 · 2020-09-21
COMPLETEDHEMolysis in a Percutaneous Axial Flow LVAD, Effects of Pentoxifylline in a Randomized Controlled TrialNCT04391231 · 2020-06-01
WITHDRAWNInterest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLSNCT04158674 · 2020-02-24
TERMINATEDA Feasibility Study on Ultrafiltration and Blood Volume MeasurementsNCT04241718 · 2019-12-19
TERMINATEDEffects of Empagliflozin on Diuresis and Renal Function in Patients With Acute Decompensated Heart FailureNCT04049045 · 2019-09-29
COMPLETEDDoes Ultrasound Assessment for Extravascular Lung Water and IVC Measurement Affect Outcomes in Inpatient Heart Failure Management?NCT04436718 · 2019-08-01
UNKNOWNSVC Occlusion in Subjects With Acute Decompensated Heart FailureNCT03836079 · 2019-07-31
COMPLETEDUse of POC Pocket Ultrasound in the Estimation of Left and Right Atrial PressuresNCT03897647 · 2019-07-31
WITHDRAWNExploring Diuretics Effective Management in Acute Decompensated Heart Failure, EDEMA TrialNCT03863626 · 2019-03-31
UNKNOWNCommon interventions
PlaceboDRUG12AcetazolamideDRUG4metolazoneDRUG3CPNS TherapyDEVICE2Doraya catheterDEVICE2Lung UltrasoundDIAGNOSTIC_TEST2Reprieve Decongestion Management SystemDEVICE2Reprieve SystemDEVICE2Standard of careOTHER2ultrafiltrationPROCEDURE2accepting the operation process of automated intelligent education software systemBEHAVIORAL1AcetazolamideOTHER1Addition of oral MetolazoneDRUG1Admission in the Cardiac Intensive Care Unit (CICU)OTHER1AliskirenDRUG1Aquadex FlexFlow System and BVA-100DEVICE1AquaPassDEVICE1ASSIST-HF AI- algorithmOTHER1Atibuclimab (IC14)DRUG1Attention ControlBEHAVIORAL1AVIVO™ PiiX Patch Monitor SystemDEVICE1BMS-986259DRUG1BVA-100DIAGNOSTIC_TEST1calculation of the inferior vena cava collapsibility indexDIAGNOSTIC_TEST1Cardiac Perfusion and Metabolism with [11C] Acetate PET/CTDRUG1
Leading sponsors
Reprieve Cardiovascular, Inc4Abiomed Inc.3Alere San Diego2Cairo University2Cardionomic Inc.2Guangdong Provincial People's Hospital2Maastricht University Medical Center2Nile Therapeutics2Revamp Medical Ltd.2Universitas Diponegoro2Universität des Saarlandes2University of Monastir2University of North Carolina, Chapel Hill2Ziekenhuis Oost-Limburg2Aalborg University1
Trial status mix
COMPLETED51
UNKNOWN16
RECRUITING15
TERMINATED11
WITHDRAWN7
ACTIVE_NOT_RECRUITING2
NOT_YET_RECRUITING2
SUSPENDED2
Phase mix
NA43
PHASE312
PHASE211
PHASE411
PHASE13
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.