Condition
MDD
ClinicalTrials.gov condition label
Clinical trials
41 shownInhaled DMT for Major Depressive DisorderNCT07562191 · 2026-08-01
RECRUITINGtDCS: Sleep to Mood in Depression (S2M-D)NCT07572526 · 2026-06-04
RECRUITINGFeasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)NCT07111390 · 2025-08-18
RECRUITINGDose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDDNCT06828887 · 2025-04-03
RECRUITINGNUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids StatusNCT07439744 · 2025-03-01
RECRUITINGPsilocybin rTMS for Treatment Resistant DepressionNCT06132178 · 2025-01-10
RECRUITINGAt-Home tDCS as Maintenance TherapyNCT07269964 · 2024-10-01
RECRUITINGCancer Related Major Depression Treated With a Single Dose of PsilocybinNCT06319378 · 2024-04-19
RECRUITINGStress, Inflammation and Neuroimaging in Major Depressive Disorder as Compared to Premenstrual Dysphoric DisorderNCT06130371 · 2024-01-04
RECRUITINGEfficacy of Statins Among Major Depressive DisorderNCT06698666 · 2022-10-01
RECRUITINGNeural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in AdolescentsNCT05437588 · 2022-10-01
RECRUITINGIndividualized fMRI-guided TMS for DepressionNCT07804459 · 2026-09-15
NOT_YET_RECRUITINGFunctional Electrical Stimulation for MDDNCT07629050 · 2026-05-25
NOT_YET_RECRUITINGTheta Burst Stimulation for Refractory Depression in Autism Spectrum DisorderNCT06670040 · 2024-09-16
ACTIVE_NOT_RECRUITINGOperation of Brain Stimulation Equipment Under Remote Viewing Effectiveness RegistryNCT06512324 · 2024-06-27
ENROLLING_BY_INVITATIONpBFS Guided rTMS Over Different Targets for Treatment-Resistant DepressionNCT06255561 · 2024-02-20
UNKNOWNResonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive DisorderNCT06572683 · 2024-02-12
ENROLLING_BY_INVITATIONTake-home Functional Electrical Stimulation for MDDNCT06261177 · 2023-12-04
ACTIVE_NOT_RECRUITINGrTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFSNCT06095778 · 2023-11-06
UNKNOWNpBFS-Guided rTMS Therapy Over Different Targets for Treatment-Resistant DepressionNCT05976009 · 2023-08-29
UNKNOWNpBFS Guided VS "5-cm Rule" rTMS Over DLPFC for MDDNCT05964023 · 2023-08-20
UNKNOWNpBFS Guided rTMS Therapy Over Different Targets for Treatment-Resistant DepressionNCT05976022 · 2023-08-04
UNKNOWNExtended Reality Behavioral Activation: An Intervention for Major Depressive DisorderNCT05525390 · 2022-12-19
COMPLETEDXanamem® in Adults With Major Depressive Disorder and Impaired Cognition (XanaCIDD)NCT05657691 · 2022-11-28
COMPLETEDThe MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD)NCT04279522 · 2021-08-31
COMPLETEDMechanism of Action of tACS for the Treatment of MDDNCT03994081 · 2021-06-09
COMPLETEDEffect of Magnesium Supplementation in Selective Serotonin Reuptake Inhibitors Treated Major Depressive Disorder PatientsNCT04880460 · 2021-03-18
COMPLETEDVirtual Reality Behavioral Activation: An Intervention for Major Depressive DisorderNCT04268316 · 2020-05-18
COMPLETEDThree Dosing Regimens of Dextromethorphan (DXM) Reportedly Used in Major Depressive DisorderNCT04226352 · 2020-03-15
COMPLETEDVortioxetine in Patients With Depression Coexisting With General Anxiety Disorder (GAD)NCT04220996 · 2019-12-27
COMPLETEDEffect of Zinc Supplementation on Depression in SSRI-treated Major Depressive Disorder PatientsNCT04482296 · 2019-09-15
COMPLETEDMaintenance Transcranial Magnetic Stimulation in Major Depressive DisorderNCT04076644 · 2019-09-01
COMPLETEDEffect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking StudyNCT04071886 · 2019-09-01
UNKNOWNEffect of Vitamin D Administration Along With SSRIs in Patients With Major Depressive DisorderNCT03754712 · 2018-03-10
UNKNOWNA Six Week, Randomized, Double-Blind Placebo-Controlled, Suvorexant Augmentation Study of Antidepressant Treatment of Major Depressive Disorder With Residual InsomniaNCT02669030 · 2017-03-01
UNKNOWNTranscranial Alternating Current Stimulation for Major Depressive DisorderNCT02339285 · 2015-05-07
COMPLETEDBrexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work EnvironmentNCT02013609 · 2013-11-01
COMPLETEDGlutamatergic and GABAergic Mediators of Antidepressant Response in Major DepressionNCT01557946 · 2012-03-01
COMPLETEDA Non Interventional Study to Investigating the Ratio of Mis-diagnosed Bipolar Symptoms in Patient With Major Depressive Disorder (MDD)NCT01344733 · 2011-05-01
COMPLETEDEvaluation of Generalization Paradigm Patterns Among Different Psychiatric DisordersNCT01501812 · 2011-03-01
UNKNOWNA Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive DisorderNCT01152554 · 2010-06-01
COMPLETEDCommon interventions
PlaceboDRUG4active rTMSDEVICE2active rTMS stimulatingDEVICE2Functional Electrical Stimulation (FES)DEVICE25-cm rTMSDEVICE160Hz Intermittent Light TherapyDEVICE1Accelerated intermittent theta burst (aiTBS) rTMS treatmentDEVICE1Active Repetitive Transcranial Magnetic Stimulation (rTMS)DEVICE1Ampa One TMS SystemDEVICE1Behavioral Activation in real-lifeBEHAVIORAL1BrexpiprazoleDRUG1citalopramDRUG1DextromethorphanDRUG1Eicosapentaenoic acid (omega-3 fatty acid)DIETARY_SUPPLEMENT1EscitalopramDRUG1Extended Reality-Enhanced Behavioral ActivationBEHAVIORAL1Generalization patternBEHAVIORAL1Genetic testingGENETIC1Low-dose psilocybinDRUG1LV232 40mgDRUG1LV232 60mgDRUG1Magnesium Glycinate tablet 200mgDIETARY_SUPPLEMENT1Mindfulness-Based TrainingBEHAVIORAL1N,N-Dimethyltryptamine (1 mg + 4 mg)DRUG1N,N-Dimethyltryptamine (15 mg + 60 mg)DRUG1
Leading sponsors
Changping Laboratory5Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh3AstraZeneca2NYU Langone Health2Stanford University2Unity Health Toronto2University of North Carolina, Chapel Hill2Actinogen Medical1Ain Shams University1Biomedical Discoveries and Neuroscientific Foundations LLC1Central South University1Children's Hospital Medical Center, Cincinnati1H. Lundbeck A/S1Institute for Advanced Medical Research, Alpharetta, GA1Johns Hopkins University1
Trial status mix
COMPLETED15
RECRUITING11
UNKNOWN9
ACTIVE_NOT_RECRUITING2
ENROLLING_BY_INVITATION2
NOT_YET_RECRUITING2
Phase mix
NA23
PHASE26
PHASE33
PHASE43
EARLY_PHASE11
PHASE11
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.