Condition
Colorectal Neoplasms
ClinicalTrials.gov condition label
How to interpret these research links
Connected source recordsThis is the original ClinicalTrials.gov condition label, found in 88 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.
Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.
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Clinical trials
60 shownA First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS MutationsNCT07629960 · 2026-06-04
RECRUITINGDETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.NCT07440290 · 2026-04-01
RECRUITINGA Study of LY4337713 in Participants With FAP-Positive Solid TumorsNCT07213791 · 2025-10-22
RECRUITINGDPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-AdjustmentNCT07158164 · 2025-08-27
RECRUITINGA Study of LY4257496 in Participants With Cancer (OMNIRAY)NCT07114601 · 2025-08-06
RECRUITINGMethylation Profile Test (Methylscape) in Body Fluids for Multi-Cancer Detection and Monitoring in ColombiaNCT07741435 · 2025-06-05
RECRUITINGA Study of DM002 in Patients With Advanced Solid TumorsNCT06751329 · 2025-02-17
RECRUITINGDiagnosis of Multiple Cancer and Monitoring of Minimal Residual Tumors After Treatment Using Blood and High-Sensitivity Genetic Analysis TechniquesNCT07035587 · 2024-08-21
RECRUITINGA Phase I/II Trial of UCB4594 in Participants With Advanced CancerNCT06380816 · 2024-07-09
RECRUITINGA Study of Sofe-M in Participants With Selected Advanced Solid TumorsNCT06400472 · 2024-05-20
RECRUITINGA Study of SGN-CEACAM5C in Adults With Advanced Solid TumorsNCT06131840 · 2023-11-20
RECRUITINGHTL0039732 in Participants With Advanced Solid TumoursNCT05944237 · 2023-08-02
RECRUITINGDETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating MutationsNCT05786716 · 2023-03-07
RECRUITINGDETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.NCT05768178 · 2023-03-01
RECRUITINGPRE-ISPY Phase I/II Oncology Platform ProgramNCT05868226 · 2023-02-15
RECRUITINGPDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical CarcinomaNCT05286814 · 2022-10-24
RECRUITINGMetarrestin (ML-246) in Subjects With Metastatic Solid TumorsNCT04222413 · 2020-10-27
RECRUITINGPersonalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching HostNCT02732860 · 2015-12-01
RECRUITINGEstablishment of a Tumor Bank for Blood SamplesNCT01763125 · 2003-11-01
RECRUITINGEstablishment of a Tumor Bank for Tissue SamplesNCT01789229 · 2003-09-01
RECRUITINGIncreasing Breast and Colorectal Cancer Screening in the CommunityNCT07748377 · 2026-10-01
NOT_YET_RECRUITINGA Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial EnrollmentNCT07814872 · 2026-09-01
NOT_YET_RECRUITINGExploratory Study on the Efficacy and Safety of Trastuzumab Rezetecan in the Treatment of HER2-Expressiong Advanced Solid TumorNCT07631884 · 2026-06-15
NOT_YET_RECRUITINGNudging Preventive Screening Via Message Framing and BundlingNCT07644910 · 2026-06-08
NOT_YET_RECRUITINGA Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.NCT07623642 · 2026-06-02
NOT_YET_RECRUITINGA Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.NCT06704724 · 2024-12-10
TERMINATEDA Study of SGN-MesoC2 in Advanced Solid TumorsNCT06466187 · 2024-08-02
TERMINATEDA Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.NCT06447662 · 2024-06-27
ACTIVE_NOT_RECRUITINGImpact on Quality of Life and Health of the CONTINUUM+ CONNECT Remote Monitoring SolutionNCT06379880 · 2024-04-25
COMPLETEDA Study of PF-08046052/SGN-EGFRd2 in Advanced Solid TumorsNCT05983133 · 2023-11-14
TERMINATEDRegorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable CancersNCT05582031 · 2023-04-30
WITHDRAWNA Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 ExpressionNCT05736731 · 2023-04-28
ACTIVE_NOT_RECRUITINGCombination Immunotherapy in Colorectal CancerNCT05571293 · 2023-03-17
ACTIVE_NOT_RECRUITINGA Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid TumorsNCT05571839 · 2023-01-03
TERMINATEDFirst in Human Study of AZD9592 in Solid TumorsNCT05647122 · 2022-12-21
ACTIVE_NOT_RECRUITINGPlatform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationNCT05358249 · 2022-10-24
ACTIVE_NOT_RECRUITINGIntravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal CarcinomatosisNCT05185947 · 2022-10-13
COMPLETEDA Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing CancerNCT05451849 · 2022-06-21
TERMINATEDStudy of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)NCT05239741 · 2022-04-02
ACTIVE_NOT_RECRUITINGSafety, Tolerability, and Anti-Tumor Activity of AFM24 in Combination With SNK01 in Subjects With Advanced/Metastatic EGFR-Expressing CancersNCT05099549 · 2021-11-03
TERMINATEDThree Birds With One StoneNCT05022511 · 2021-09-01
COMPLETEDStudy of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)NCT04956640 · 2021-07-19
ACTIVE_NOT_RECRUITINGEvaluation of a Cosmetic Product to Preserve Skin Conditions When Using Anti-EGFR Cancer TherapiesNCT04878692 · 2021-06-01
UNKNOWNA Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid TumorsNCT04644315 · 2021-05-24
TERMINATEDStudy of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)NCT04776148 · 2021-03-29
COMPLETEDA Study of SGN-STNV in Advanced Solid TumorsNCT04665921 · 2021-01-18
TERMINATEDAssessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among SurvivorsNCT03935282 · 2020-10-01
COMPLETEDA Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)NCT03948763 · 2019-06-26
TERMINATEDPredictive Value of Innovative Prognostic Markers (Gut Microbiota, Sarcopenia, Metabolic Syndrome and Obesity) on Surgical and Oncologic Results in the Management of Sporadic Colorectal Adenocarcinoma.NCT03843905 · 2018-11-15
UNKNOWNUltrasound-enhanced Delivery of Chemotherapy to Patients With Liver Metastasis From Breast- and Colorectal CancerNCT03477019 · 2018-11-12
COMPLETEDPF-06952229 Treatment in Adult Patients With Advanced Solid TumorsNCT03685591 · 2018-10-04
TERMINATEDSafety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)NCT03631407 · 2018-09-24
COMPLETEDStudy of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001)NCT03515824 · 2018-08-13
TERMINATEDEfficacy and Safety Study of Tisotumab Vedotin for Patients With Solid TumorsNCT03485209 · 2018-06-25
ACTIVE_NOT_RECRUITINGPhase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid TumorsNCT03037385 · 2017-03-17
COMPLETEDA Safety Study of SGN-2FF for Patients With Advanced Solid TumorsNCT02952989 · 2017-02-23
TERMINATEDAn Intervention Programme to Reduce Cognitive Impairment Due to CancerNCT02581709 · 2016-05-01
TERMINATEDDeterminants of Quality Of Life in AGEd Cancer PatientsNCT02672657 · 2016-02-01
UNKNOWNPreoperative High Intensity Interval Training: The PHIIT TrialNCT02674815 · 2016-02-01
COMPLETEDLimiting Chemotherapy Side Effects by Using MoxaNCT02781155 · 2016-02-01
UNKNOWNCommon interventions
pembrolizumabDRUG5BevacizumabDRUG3carboplatinDRUG3cisplatinDRUG3LeucovorinDRUG3PembrolizumabBIOLOGICAL35-Fluorouracil (5-FU)DRUG2BevacizumabCOMBINATION_PRODUCT2CarboplatinCOMBINATION_PRODUCT2CetuximabBIOLOGICAL2CetuximabCOMBINATION_PRODUCT2CetuximabDRUG2CisplatinCOMBINATION_PRODUCT2FluorouracilCOMBINATION_PRODUCT2GemcitabineCOMBINATION_PRODUCT2LeucovorinCOMBINATION_PRODUCT2Nab-paclitaxelCOMBINATION_PRODUCT2OxaliplatinCOMBINATION_PRODUCT2OxaliplatinDRUG2PaclitaxelCOMBINATION_PRODUCT2PembrolizumabCOMBINATION_PRODUCT2PemetrexedDRUG2pemetrexedCOMBINATION_PRODUCT2SasanlimabCOMBINATION_PRODUCT2trametinibDRUG2
Leading sponsors
Eli Lilly and Company
6
Cancer Research UK
5
Merck Sharp & Dohme LLC
5
National Cancer Institute (NCI)
5
Pfizer
5
Seagen, a wholly owned subsidiary of Pfizer
5
AstraZeneca
2
Hoffmann-La Roche
2
Medical University of Vienna
2
Seagen Inc.
2
Stanford University
2
A2 Biotherapeutics Inc.
1
Aarhus University Hospital
1
Achieve Life Sciences
1
AHS Cancer Control Alberta
1
Trial status mix
COMPLETED30
RECRUITING20
TERMINATED16
ACTIVE_NOT_RECRUITING9
UNKNOWN7
NOT_YET_RECRUITING5
WITHDRAWN1
Phase mix
PHASE138
PHASE238
NA13
PHASE37
PHASE41
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.