Condition

Advanced Parkinson's Disease

ClinicalTrials.gov condition label

Clinical trials19

Recruiting2

Common interventions25

Lead sponsors shown10

Clinical trials

19 shown

SAD Study in Patients With Parkinson's Disease and Motor FluctuationsNCT07422675 · 2026-02-01

A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/FoscarbidopaNCT07284342 · 2025-11-17

An Automated Navigation System for Deep Brain Electrode ImplantationNCT06396494 · 2024-01-01

A Study on the Safety and Tolerability of RGL-193 in Patients With Advanced Parkinson's DiseaseNCT06195124 · 2023-12-01

Phase 1 Safety and Tolerability Study of MSK-DA01 Cell Therapy for Advanced Parkinson's DiseaseNCT04802733 · 2021-05-03

A Study to Assess the PK and Pharmacodynamics of IPX203 in Subjects With Advanced Parkinson's DiseaseNCT03007888 · 2016-11-14

Observational Study Evaluating Long-Term Effectiveness of Duodopa/Duopa in Patients With Advanced Parkinson's DiseaseNCT02611713 · 2016-01-04

A Study to Examine the Effect of Levodopa-Carbidopa Intestinal Gel (LCIG) Therapy Relative to That of Optimized Medical Treatment (OMT) on Non-motor Symptoms (NMS) Associated With Advanced Parkinson's Disease (PD)NCT02549092 · 2015-10-26

An Extension Study to Assess the Safety, Tolerability and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease and Persistent Motor-Complications Despite Optimized Treatment With Available Anti-Parkinsonian MedicationsNCT02082249 · 2014-03-10

A Study to Assess the Efficacy, Safety and Tolerability of ABT-SLV187 Monotherapy in Subjects With Advanced Parkinson's Disease (PD) and Persistent Motor Complications, Despite Optimized Treatment With Available Anti-Parkinsonian MedicationsNCT01960842 · 2013-10-01

Clinical Study for Adaptive Deep Brain Stimulation (aDBS)Controlled by Intracerebral Activity in Parkinson's DiseaseNCT02154724 · 2013-09-01

A Study to Assess the Safety and Efficacy of Levodopa-carbidopa Intestinal Gel (LCIG) for the Treatment of Non-motor Symptoms in Patients With Advanced Parkinson's DiseaseNCT01736176 · 2013-03-01

A Phase 3b, Open-Label, Safety and Efficacy Study of Rotigotine as Add-On Therapy With Low Doses of Pramipexole or Ropinirole in Patients With Advanced Parkinson's DiseaseNCT01723904 · 2012-10-01

Effect of Rotigotine on Motor Symptoms in Patients With Advanced Parkinson's Disease (PD) With Motor Fluctuations and Symptoms of Gastrointestinal DysfunctionNCT01536015 · 2012-01-01

Study of Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's DiseaseNCT01479127 · 2011-10-01

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's SubjectsNCT00660387 · 2009-12-01

Open Label Continuation Treatment Study With Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson's DiseaseNCT00660673 · 2009-11-13

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's SubjectsNCT00357994 · 2009-01-01

Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's DiseaseNCT00335153 · 2008-01-01

Common interventions

Leading sponsors

AbbVie6 AbbVie (prior sponsor, Abbott)5 Beijing Tiantan Hospital1 BlueRock Therapeutics1 Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico1 Impax Laboratories, LLC1 Second Affiliated Hospital of Soochow University1 Serina Therapeutics1 UCB BIOSCIENCES GmbH1 UCB Pharma1

Trial status mix

COMPLETED13

UNKNOWN3

RECRUITING2

TERMINATED1

Phase mix

PHASE310

PHASE12

PHASE22

EARLY_PHASE11

NA1

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.