Condition
Hepatic Impairment
ClinicalTrials.gov condition label
How to interpret these research links
Connected source recordsThis is the original ClinicalTrials.gov condition label, found in 10 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.
Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.
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Clinical trials
10 shownA PK Study Testing Single Oral Dose of Elacestrant in Subjects With Normal or Severely Impaired Hepatic FunctionNCT06126575 · 2023-03-13
COMPLETEDPharmacokinetics of Single-dose Dolutegravir in HIV-seronegative Subjects With Severe Hepatic Impairment Compared to Matched Controls.NCT03813979 · 2020-11-15
WITHDRAWNThe Role and Dynamics of Liver Dysfunction in Patients Undergoing Cardiac SurgeryNCT02893657 · 2017-12-01
UNKNOWNPharmacokinetics, Safety, and Tolerability of Ertugliflozin (MK-8835/PF-04971729) in Participants With Hepatic Impairment and in Healthy Participants (MK-8835-014)NCT02115347 · 2014-09-19
COMPLETEDPharmacokinetics of AGO178 in Participants With Liver ImpairmentNCT01531309 · 2011-02-08
COMPLETEDGSK1349572 Hepatic Impairment StudyNCT01231529 · 2010-11-19
COMPLETEDA Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Hepatic Impairment Patients and Healthy VolunteersNCT01146938 · 2010-05-01
COMPLETEDTMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function.NCT00736905 · 2008-06-01
COMPLETEDPharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic ImpairmentNCT00162097 · 2004-11-01
COMPLETEDA Study of the Pharmacokinetics of Paliperidone in Volunteers With Normal or Impaired Liver FunctionNCT00791284 · 2004-08-01
COMPLETEDCommon interventions
Leading sponsors
Boryung Pharmaceutical Co., Ltd
1
Bristol-Myers Squibb
1
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
1
Merck Sharp & Dohme LLC
1
Novartis Pharmaceuticals
1
Radboud University Medical Center
1
Semmelweis University Heart and Vascular Center
1
Stemline Therapeutics, Inc.
1
Tibotec Pharmaceuticals, Ireland
1
ViiV Healthcare
1
Trial status mix
COMPLETED8
UNKNOWN1
WITHDRAWN1
Phase mix
PHASE18
PHASE41
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.