Condition
Hypercapnia
ClinicalTrials.gov condition label
Explore related research
Search across original and mapped recordsSearch results distinguish clinical terminology from original registry names. Shared trial participation does not imply treatment or approval.
How to interpret these research links
Connected source recordsThis is the original ClinicalTrials.gov condition label, found in 25 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.
Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.
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Clinical trials
25 shownHow Nocturnal Hypoventilation Predicts Long-term Response to Non-invasive Ventilation in Hypercapnic COPD PatientsNCT07414108 · 2025-12-10
RECRUITINGMedical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.NCT07432191 · 2025-05-29
RECRUITINGRespiratory Strategies in COPD Patients With Persistent Hypercapnia Following ExacerbationNCT07065799 · 2024-06-30
RECRUITINGDUET Versus Standard Interface for Hypercapnic COPD PatientsNCT05829083 · 2023-07-18
RECRUITINGRemote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory SupportNCT07751003 · 2027-08-01
NOT_YET_RECRUITINGCombination of High-flow Nasal Oxygen (Optiflow) and Vibrating Membrane Nebuliser (Aerogen) in the Pre-hospital Setting - Before/After StudyNCT07791992 · 2026-10-01
WITHDRAWNEffectiveness and Efficiency of Home Telemonitoring and Non-invasive Ventilation in Patients With COPD and Hypercapnia (EVALECO)NCT07679646 · 2026-07-01
NOT_YET_RECRUITINGImpact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From Assiut University HospitalNCT07198880 · 2026-01-01
NOT_YET_RECRUITINGComfort of Patients Under Non Invasive Ventilation According to the MaskNCT06212180 · 2024-01-01
UNKNOWNNon-invasive Home Ventilation in Patients With Severe Hypercapnic Chronic Obstructive Pulmonary DiseaseNCT03934749 · 2019-06-27
TERMINATEDImpact of Non-invasive Ventilation in Hypercapnic COPDNCT03522805 · 2018-04-23
TERMINATEDSleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD OutpatientsNCT03221387 · 2017-09-10
COMPLETEDPostoperative Complications in Patients With Obesity Hypoventilation SyndromeNCT02980770 · 2016-11-01
UNKNOWNEvaluation of the Risk of Hyperoxia-induced Hypercapnia in Obese Cardiac Surgery PatientsNCT02917668 · 2016-09-01
COMPLETEDThe Effect of Non-invasive Ventilation on the Oxygenation of Peripheral Muscle in Hypercapnic COPD PatientsNCT02877290 · 2016-08-01
COMPLETEDAdaptive Non-invasive Ventilation to Abolish Tidal Flow LimitationNCT04497090 · 2014-10-23
COMPLETEDIntrinsic Periodic Pattern of BreathingNCT02201875 · 2014-09-01
UNKNOWNClosed-loop System for Oxygen Delivery and Exercise in Chronic Obstructive Pulmonary DiseaseNCT01575327 · 2012-07-01
COMPLETEDSTIT-2: Evaluation of Safety and Efficacy of Short-time TNI® Treatment in Patients With COPD and HypercapniaNCT01693146 · 2011-12-01
UNKNOWNNocturnal Transnasal Insufflation (nTNI)NCT01499550 · 2011-08-01
COMPLETEDPhysiological and Clinical Changes in NHF TherapyNCT02504814 · 2011-06-01
COMPLETED"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"NCT01317329 · 2011-03-01
COMPLETEDChanges in Blood Gases, Disturbance of Breath During Sleep and Cardiovascular Co-morbidity in COPD PatientsNCT00888342 · 2009-05-01
COMPLETEDPulmonary Rehabilitation in Patients Before Lung Transplantation (LTx)NCT00962078 · 2008-07-01
COMPLETEDNon-invasive Ventilation in Severe Chronic Obstructive Pulmonary Disease(COPD)NCT00710541 · 2004-10-01
TERMINATEDCommon interventions
alcoholOTHER1Asymmetric nasal cannula - DUETDEVICE1auto-EPAPDEVICE1Automated settings on the oxygen delivery deviceDEVICE1BiPAP device (non invasive ventilation)DEVICE1Clinically prescribed CPAP therapyOTHER1continuous endurance trainingOTHER1Conventional nasal high flow cannulaDEVICE1fixed-EPAPDEVICE1FreeO2OTHER1Group 1: NHF/LTOTDEVICE1Group 2: HMV/LTOTDEVICE1High-intensity non-invasive ventilationDEVICE1Home Non-Invasive Ventilation and TelemonitoringDEVICE1Humidified nasal high flow with oxygenDEVICE1humidified transnasal insufflation (TNI20oxy)DEVICE1INBENTUS VERSATILEDEVICE1interval trainingOTHER1Manual settings with FreeO2 system in collection modeDEVICE1maskDEVICE1Nasal Highflow (NHF)DEVICE1Nasal insufflation of oxygenDEVICE1Nasal oxygen insufflation with a TNI® 20 oxy deviceDEVICE1nebulizer mask and oxygen therapy of 6 to 9 liters per minuteDEVICE1Non Invasive VentilationDEVICE1
Mapped drugs appearing in these trials
Shared trial participation only; not evidence of efficacy or approval.
Leading sponsors
IRCCS Azienda Ospedaliero-Universitaria di Bologna
2
Schön Klinik Berchtesgadener Land
2
AGIR à Dom
1
Air Liquide Healthcare Spain
1
Assistance Publique - Hôpitaux de Paris
1
Assiut University
1
Association pour la Recherche en Physiologie de l'Environnement
1
Centre Hospitalier Sud Francilien
1
Centre Hospitalier Universitaire de Besancon
1
Deutsche Lungenstiftung e.V.
1
Iconic Solutions By Murcia SL
1
Institut für Pneumologie Hagen Ambrock eV
1
Larissa University Hospital
1
Laval University
1
LHL Helse
1
Trial status mix
COMPLETED10
RECRUITING4
UNKNOWN4
NOT_YET_RECRUITING3
TERMINATED3
WITHDRAWN1
Phase mix
NA17
PHASE11
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.