Condition

Idiopathic Intracranial Hypertension

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 23 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials23

Recruiting1

Common interventions25

Lead sponsors shown15

Clinical trials

23 shown

Prospective Ocular Imaging for Intracranial Pressure EvaluationNCT06855342 · 2025-01-10

Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary ManagementNCT07707544 · 2026-06-01

ACTIVE_NOT_RECRUITING

Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical ApproachesNCT06856850 · 2025-02-27

ACTIVE_NOT_RECRUITING

ICP & Outflow StudyNCT06436820 · 2024-06-01

Ocular Perfusion in Patients With Idiopathic Intracranial HypertensionNCT06545981 · 2024-05-28

Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension TreatmentNCT06361823 · 2024-05-01

Biomarkers in the Etiology of Idiopathic Intracranial HypertensionNCT06059703 · 2023-11-27

MR Lymphatic Imaging in Idiopathic Intracranial HypertentionNCT05762367 · 2023-03-10

A Trial to Determine the Efficacy and Safety of Presendin in IIHNCT05347147 · 2022-11-18

The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial PressureNCT06027567 · 2022-09-02

Outcome of Cerebral Venous Sinuses Stenting on Idiopathic Intracranial HypertensionNCT05308823 · 2022-03-15

Assessment of ICP in Idiopathic Intracranial Hypertension Using Transocular Ultrasound and Transcranial DopplerNCT04314128 · 2020-01-01

The Effects of MAP and EtCO2 on Venous Sinus PressuresNCT03867461 · 2019-06-20

Surgical Idiopathic Intracranial Hypertension Treatment TrialNCT03501966 · 2019-02-06

Venous Sinus Stenting With the River Stent in IIHNCT03556085 · 2018-08-24

ACTIVE_NOT_RECRUITING

Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial HypertensionNCT03963336 · 2017-07-22

Evaluating Raised Intracranial Pressure Using MR ElastographyNCT03096743 · 2017-01-10

ACTIVE_NOT_RECRUITING

Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary SyndromeNCT02896452 · 2016-10-01

ACTIVE_NOT_RECRUITING

Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure MeasurementNCT01863381 · 2014-09-01

Safety and Effectiveness of 11b-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) to Treat Idiopathic Intracranial Hypertension.NCT02017444 · 2014-04-25

An RCT of Bariatric Surgery vs a Community Weight Loss Programme for the Sustained Treatment of IIHNCT02124486 · 2014-03-06

Stenting of Venous Sinus Stenosis for Medically Refractory Idiopathic Intracranial HypertensionNCT02143258 · 2014-03-01

Idiopathic Intracranial Hypertension Treatment TrialNCT01003639 · 2010-01-01

Common interventions

AcetazolamideDRUG3 Lumbar puncturePROCEDURE2 PlaceboDRUG2 SemaglutideDRUG2 3T MRI with Gadobutrol injectionDIAGNOSTIC_TEST1 Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range)OTHER1 Adjustment to end-tidal carbon dioxide concentrations (24-26 mmHg range)OTHER1 Adjustment to Mean Arterial Pressure (100-110 mmHg range)OTHER1 Adjustment to Mean Arterial Pressure (60-80 mmHg range)OTHER1 AZD4017DRUG1 Bariatric surgeryPROCEDURE1 Blood punctionPROCEDURE1 Central blood samplingPROCEDURE1 Conservative Management: Centered on lifestyle modifications for weight reduction, alongside targeted medical therapies including carbonic anhydrase inhibitors (e.g., acetazolamide) and/or topiramate.DRUG1 Dietetic interventionBEHAVIORAL1 Dietician counsellingBEHAVIORAL1 DPOAEDEVICE1 Formal weight loss counselling programBEHAVIORAL1 Intracranial pressure measurementPROCEDURE1 LMWHDRUG1 Low calorie dietDIETARY_SUPPLEMENT1 Lumbar puncture and administration of medicationOTHER1 lumbo-peritoneal shuntPROCEDURE1 MR elastographyDIAGNOSTIC_TEST1 MRI structural brain imagingDIAGNOSTIC_TEST1

Leading sponsors

University of Birmingham 2 Al-Azhar University 1 Capital Medical University 1 Danish Headache Center 1 Fayoum University 1 Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 1 Guy's and St Thomas' NHS Foundation Trust 1 Institut National de la Santé Et de la Recherche Médicale, France 1 Invex Therapeutics Ltd. 1 Jaeb Center for Health Research 1 King's College Hospital NHS Trust 1 LifeBridge Health 1 Mayo Clinic 1 Medical University of Vienna 1 National Aeronautics and Space Administration 1

Trial status mix

COMPLETED7

UNKNOWN7

ACTIVE_NOT_RECRUITING5

TERMINATED3

RECRUITING1

Phase mix

NA11

PHASE34

PHASE22

EARLY_PHASE11

PHASE41

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.