Condition

Insulin Resistance

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 711 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials711

Recruiting57

Common interventions25

Lead sponsors shown15

Clinical trials

60 shown

Alpelisib Challenge Test (ACT)NCT07778524 · 2026-09-02

Prebiotic Inulin for Late-Reproductive IndividualsNCT07724522 · 2026-08-01

Sleep Loss and Circadian Misalignment - Mechanisms of Insulin ResistanceNCT07494084 · 2026-07-16

DIabetes GLycemic Assessment in Newly Confirmed EpisodesNCT07690163 · 2026-07-15

Effect of Insulin Lowering on LipogenesisNCT07403604 · 2026-07-01

PREdiabetes GLycemic Impact and Data EvaluationNCT07599072 · 2026-07-01

Food and Metabolism StudyNCT07624500 · 2026-06-03

Kodo Millet Porridge and Its Effects on Gut Health and Metabolic SyndromeNCT07703371 · 2026-06-01

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIVNCT07226128 · 2026-04-10

MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/ObesityNCT07505745 · 2026-02-02

Cardiometabolic Disease and Substrate MetabolismNCT07565727 · 2025-12-10

Effects of Ketone Bodies on Insulin SensitivityNCT07359625 · 2025-12-02

ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early AdolescenceNCT07102797 · 2025-11-24

New Mechanisms of ObesityNCT06768827 · 2025-11-13

A Sensory Strategy to Cut Sugary Beverages in African/American and Latine AdolescentsNCT07223151 · 2025-07-25

Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)NCT07297290 · 2025-07-23

Effects of Cranberry on Gut and Metabolic HealthNCT07460856 · 2025-07-07

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled TrialNCT06138821 · 2025-06-24

The Muscle Monitor: Early Skeletal Muscle Indicators of Insulin Resistance and Cardiometabolic RiskNCT07678736 · 2025-05-19

Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with ObesityNCT06847373 · 2025-03-01

Alternative Physical Activity Strategies for Breast Cancer SurvivorsNCT06633380 · 2024-10-22

Electro-Acupuncture for Obese Patients With Insulin ResistanceNCT06609200 · 2024-10-10

Prenatal Exercise and Glucose RegulationNCT07802262 · 2024-09-24

Graded Insulin Suppression Test P&FNCT06592261 · 2024-09-16

Neuromuscular Electrical Stimulation: A Novel Treatment for Improving MetabolismNCT06722391 · 2024-08-19

Effect of GLP1 Receptor Agonist on Brain Insulin ResponsivenessNCT06487832 · 2024-07-01

Characteristics of Papez Loop Neural Network in T2DM （Type 2 Diabetes Mellitus）NCT06912321 · 2024-05-01

Human Models of Selective Insulin Resistance: Alpelisib, Part INCT06354088 · 2024-04-24

Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS DiagnosisNCT05950282 · 2024-02-01

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) SignalingNCT06129110 · 2024-01-31

The Acute T-Rex (Timing of Resistance Exercise) StudyNCT06366399 · 2023-11-15

Exercise Training on Brain Insulin ResponsivenessNCT06039787 · 2023-10-20

Effect of Timed-Restricted Eating on Metabolic HealthNCT06061042 · 2023-10-01

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKDNCT04984226 · 2023-09-08

Understanding Metabolism and Inflammation Risks for Diabetes in AdolescentsNCT06007404 · 2023-09-06

Metabolic Adaptations to Weight Loss With and Without ExerciseNCT05806801 · 2023-07-19

Small Extracellular Vesicles and Insulin ActionNCT05933707 · 2023-06-14

Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2NCT05833217 · 2023-06-06

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 DiabetesNCT05543083 · 2023-06-02

Effects of Oral Glutamine Supplementation on Insulin Resistance and Functional Intestinal Disorders in Obese Patients.NCT04883515 · 2023-03-01

Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical ExerciseNCT06959043 · 2022-11-22

Improving Glycemic Control With Electrical StimulationNCT03947697 · 2022-08-09

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)NCT05277558 · 2022-05-24

Mitochondrial Substrate Utilization in the Diabetic Human HeartNCT05958706 · 2021-12-01

Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin ResistanceNCT04578652 · 2021-10-22

Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) CohortNCT06167135 · 2021-09-10

Mitigating the Pro-inflammatory Phenotype of ObesityNCT04934228 · 2021-07-01

Exercise Effects on Adipose Tissue Structure and FunctionNCT04812314 · 2021-03-01

Pregnancy Outcomes: Effects of Metformin Study (POEM Study)NCT02947503 · 2019-11-26

Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style InterventionNCT03875625 · 2019-04-01

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin ResistanceNCT05165706 · 2019-01-31

Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMINCT05046483 · 2018-12-30

Metabolic and Bone Changes After Adjuvant Cancer Treatments in Early Non-metastatic Breast CancerNCT03784651 · 2018-12-17

Collection of Human Metabolic TissuesNCT02861781 · 2016-02-02

Metabolic Effects of Angiotensin-(1-7)NCT02646475 · 2016-02-01

Study of the Effect of Innate on the Inflammatory Response to EndotoxinNCT01143480 · 2012-07-30

Leipzig Adipose Tissue Childhood CohortNCT02208141 · 2010-10-01

Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin ResistanceNCT04062890 · 2030-04-15

Human Models of Selective Insulin Resistance: Pancreatic ClampNCT06558422 · 2027-01-01

NOT_YET_RECRUITING

The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM)NCT07664501 · 2027-01-01

NOT_YET_RECRUITING

Common interventions

Leading sponsors

Stanford University 21 Maastricht University Medical Center 15 Columbia University 13 National Heart, Lung, and Blood Institute (NHLBI) 13 Washington University School of Medicine 12 Mayo Clinic 11 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 10 University of Aarhus 10 Yale University 10 Massachusetts General Hospital 8 Pennington Biomedical Research Center 8 University Hospital Tuebingen 8 University of Alabama at Birmingham 8 University of California, San Francisco 7 University of Missouri-Columbia 7

Trial status mix

COMPLETED488

UNKNOWN74

RECRUITING57

TERMINATED27

WITHDRAWN21

ACTIVE_NOT_RECRUITING19

NOT_YET_RECRUITING15

ENROLLING_BY_INVITATION5

SUSPENDED5

Phase mix

NA387

PHASE260

PHASE448

PHASE144

PHASE331

EARLY_PHASE110

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.