Condition

Left Bundle-Branch Block

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 25 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials25

Recruiting6

Common interventions25

Lead sponsors shown15

Clinical trials

25 shown

Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT NonrespondersNCT05760924 · 2024-11-01

Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure PatientsNCT05769036 · 2023-10-01

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy AssessmentNCT05327062 · 2023-03-06

ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System PacingNCT06324682 · 2023-01-01

Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Block With Cardiac Resynchronization TherapyNCT05564689 · 2022-09-29

Prediction of Outcome by Echocardiography in Left Bundle Branch BlockNCT04293471 · 2021-04-15

Left Bundle Branch Area Pacing in Patients With Heart FailureNCT06488989 · 2024-06-01

HIS Alternative II - UK SiteNCT05814263 · 2023-12-01

REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)NCT05652218 · 2023-02-26

ACTIVE_NOT_RECRUITING

Conduction System Pacing Versus Biventricular Resynchronization in Patients With Chronic Heart FailureNCT05572736 · 2022-11-07

LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBBNCT05572957 · 2022-10-14

ACTIVE_NOT_RECRUITING

The Left Bundle Cardiac Resynchronization Therapy TrialNCT05434962 · 2022-06-27

ACTIVE_NOT_RECRUITING

Conduction System Pacing Versus Biventricular Pacing for Cardiac ResYNChronizationNCT05155865 · 2022-01-10

Direct HIS/LBB Pacing as an Alternative to Biventricular Pacing in Patients With HFrEF and a Typical LBBB.NCT04409119 · 2020-06-01

Mid-Q Response StudyNCT04180696 · 2020-01-23

Optimised MultiSite Pacing Vector StudyNCT03938090 · 2019-12-01

Mechanisms and Innovations in Cardiac Resynchronisation TherapyNCT04221763 · 2019-10-15

Mapping and Pacing of the His Bundle for Heart Failure Patients With Left Bundle Branch BlockNCT03803995 · 2019-03-20

LV Only MPP With SyncAVNCT03567096 · 2018-10-09

Direct HIS-pacing as an Alternative to BiV-pacing in Symptomatic HFrEF Patients With True LBBBNCT03614169 · 2018-09-09

Optimizing CRT With ECGINCT03492788 · 2017-12-28

Left Ventricular Septal Pacing: Potential Application for Cardiac Resynchronization TherapyNCT03415945 · 2017-11-23

LV Endocardial CRT for Patients With Intermediate QRS WidthNCT03573427 · 2016-04-28

Tailor-CRT: Better Application of Cardiac Resynchronization TherapyNCT02326493 · 2014-11-01

Resynchronization in Paced Heart Failure Patients With Implantable Cardioverter Defibrillator (ICD) IndicationNCT01415024 · 2011-05-01

Common interventions

Cardiac resynchronization therapyDEVICE2 HIS/LBB pacingDEVICE2 LV pacingDEVICE2 aCRT OFFDEVICE1 aCRT ONDEVICE1 BiV pacing with MPP and SyncAVDEVICE1 BIV-CRTDEVICE1 Biventricular pacingDEVICE1 Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD)DEVICE1 Cardiac pacing - Conduction System PacingDEVICE1 Cardiac pacing - Conventional RV pacingDEVICE1 Cardiac pacing - Epicardial pacingDEVICE1 Cardiac pacing - Leadless pacingDEVICE1 Cardiac resynchronization therapy (CRT)DEVICE1 Cardiac Resynchronization Therapy Devices with Defibrillator Function (CRT-D) or CRT-D Leads ReplacementDEVICE1 Cardiac resynchronization therapy with biventricular stimulationDEVICE1 Conduction system pacingDEVICE1 CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessmentDEVICE1 CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right and Left Ventricular PacingDEVICE1 CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right Ventricular PacingDEVICE1 ECGI-optimized VV-offsetOTHER1 Guideline-Directed Medical Therapy(GDMT)DRUG1 His-bundle pacing.DEVICE1 Implantation of a HIS-pacing leadPROCEDURE1 Implantation of a LV-pacing leadPROCEDURE1

Leading sponsors

Abbott Medical Devices 2 Copenhagen University Hospital, Rigshospitalet 2 Maastricht University Medical Center 2 Tomsk National Research Medical Center of the Russian Academy of Sciences 2 Ashkan Eftekhari 1 Barts & The London NHS Trust 1 Hospital Moinhos de Vento 1 Imperial College Healthcare NHS Trust 1 Imperial College London 1 Inova Health Care Services 1 Jaimie Manlucu 1 Medtronic Cardiac Rhythm and Heart Failure 1 National Research Center for Cardiac Surgery, Kazakhstan 1 Óscar Cano Pérez 1 Schuechtermann-Klinik 1

Trial status mix

COMPLETED9

RECRUITING6

UNKNOWN4

ACTIVE_NOT_RECRUITING3

WITHDRAWN2

TERMINATED1

Phase mix

NA20

PHASE41

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.