Condition

Painful Diabetic Neuropathy

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 57 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials57

Recruiting4

Common interventions25

Lead sponsors shown15

Clinical trials

57 shown

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial DiseaseNCT06480786 · 2024-12-18

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMANCT05754190 · 2023-06-20

Low-Dose Naltrexone for the Treatment of Painful Diabetic NeuropathyNCT04678895 · 2020-12-22

Peripheral Nerve Block in Patients With Painful Diabetic PolyneuropathyNCT04699734 · 2020-09-08

Observational Study to Evaluate the Efficacy of Sustained QUTENZA® Use in Painful Diabetic Peripheral NeuropathyNCT06495424 · 2025-03-14

ACTIVE_NOT_RECRUITING

Feasibility of Self-treatment of Painful Diabetic Neuropathy Using Electrical Vasomotor Nerve StimulationNCT06524284 · 2024-07-22

A Study to Evaluate Pregabalin in Painful Diabetic Peripheral NeuropathyNCT06383702 · 2024-05-15

Multimodal Intervention for Painful Diabetic Neuropathy: NeuOst Feasibility TrialNCT06423391 · 2024-04-30

Treatment for Painful Diabetic NeuropathyNCT05937984 · 2023-10-01

BurstDR Stimulation for Painful Diabetic NeuropathyNCT05985291 · 2023-07-03

Pain and Neurological Function Improvements With 10 kHz Spinal Cord Stimulation Treatment of Painful Diabetic NeuropathyNCT05777317 · 2023-04-24

ACTIVE_NOT_RECRUITING

Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic StudyNCT05993871 · 2023-01-01

Axon Therapy and Conventional Medical Management for Painful Diabetic Neuropathy Compared to Sham and Conventional Medical ManagementNCT05620225 · 2022-12-15

EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISANCT05480228 · 2022-09-21

EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral NeuropathyNCT05476276 · 2022-09-21

The Therapeutic Effect of Low-intensity Focused Ultrasound on Painful Diabetic Peripheral NeuropathyNCT05624762 · 2022-07-07

Microvascular Dysfunction in Diabetic Peripheral NeuropathyNCT05118217 · 2021-11-18

Vitamin D and Painful Diabetic NeuropathyNCT05080530 · 2021-10-29

Safety, Tolerability & Pharmacokinetics Study of CNTX-6016 in Healthy Subjects and Subjects With PDNNCT04857957 · 2021-04-14

A 12-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Painful Peripheral NeuropathyNCT04786340 · 2020-11-20

The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy PatientNCT04689958 · 2020-11-03

The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy PatientNCT04689984 · 2020-11-03

The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy PatientNCT04689971 · 2020-11-03

Efficacy and Safety of VM202 in Painful Diabetic Peripheral Neuropathy -The HOPES TrialNCT04087941 · 2019-11-01

A 24-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Peripheral NeuropathyNCT04005287 · 2019-10-15

Injection of Subcutaneous Glucose 10% in Small Shots is Effective in the Treatment of Diabetic Neuropathic PainNCT04097691 · 2019-07-14

Extension of Phase 3 Gene Therapy for Painful Diabetic NeuropathyNCT04055090 · 2019-02-04

Trazodone/Gabapentin Fixed Dose Combination Products in Painful Diabetic NeuropathyNCT03749642 · 2018-11-22

Quantitative Assessment of Painful Diabetic Peripheral Neuropathy After High Frequency Spinal Cord StimulationNCT03769675 · 2018-11-20

Efficacy and Safety of MEDI7352 in Participants With Painful Diabetic NeuropathyNCT03755934 · 2018-11-19

The Development of Contextual Cognitive Behavioural Approach to PDNNCT03700528 · 2018-10-01

Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy (PDN)NCT03297294 · 2018-03-14

An Evaluation of an SCCD on the Symptomatology of Painful DPNNCT03331614 · 2017-10-15

Comparison of 10 kHz SCS Combined With CMM to CMM Alone in the Treatment of Neuropathic Limb PainNCT03228420 · 2017-07-20

Graded Exposure in Patients With Painful Diabetic NeuropathyNCT03066570 · 2017-06-01

Trazodone in Painful Diabetic NeuropathyNCT03202979 · 2017-05-16

Functional Magnetic Resonance Imaging of Brain Activity in Patients With Painful Diabetic NeuropathyNCT03700502 · 2016-06-05

Phase 3 Gene Therapy for Painful Diabetic NeuropathyNCT02427464 · 2016-04-01

The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic NeuropathyNCT02643251 · 2015-12-01

A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic NeuropathyNCT02355158 · 2014-06-01

Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic NeuropathyNCT02068027 · 2014-03-01

A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral NeuropathyNCT01521598 · 2012-01-01

Eslicarbazepine Acetate as Therapy in Diabetic Neuropathic PainNCT01129960 · 2010-11-01

A Trial in Painful Diabetic Peripheral Neuropathy With GRT3983YNCT01056315 · 2009-11-01

Capsaicin Nanoparticle in Patient With Painful Diabetic NeuropathyNCT01125215 · 2009-09-01

A Study of Single Dose Pain Therapy in Patients With Painful Diabetic Neuropathy (0000-115)NCT00837941 · 2009-04-01

Efficacy of Inhaled Cannabis in Diabetic Painful Peripheral NeuropathyNCT00781001 · 2008-07-01

Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic NeuropathyNCT00695565 · 2008-05-01

Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve CompressionNCT00703209 · 2008-01-01

Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Painful Diabetic NeuropathyNCT00980746 · 2007-11-01

A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic NeuropathyNCT00350103 · 2006-06-30

A Trial to Assess the Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic NeuropathyNCT00220337 · 2004-12-21

Study Evaluating Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.NCT00546351 · 2004-05-01

An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic NeuropathyNCT00861042 · 2002-04-01

Electromagnetic Stimulation (FREMS) in Patients With Painful Diabetic NeuropathyNCT00337324 · 2002-03-01

A Trial to Investigate Safety and Efficacy of SPM927 in Painful Diabetic NeuropathyNCT00861445 · 2001-06-01

A Clinical Trial to Study the Effects of GRC 17536 in Patients With Painful Diabetic Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients)NCT01556152

Common interventions

Leading sponsors

UCB Pharma 5 BioDelivery Sciences International 3 Duta Wacana Christian University 3 Aziende Chimiche Riunite Angelini Francesco S.p.A 2 Bial - Portela C S.A. 2 Helixmith Co., Ltd. 2 James P. Rathmell, MD 2 Nevro Corp 2 WinSanTor, Inc 2 Arcion Therapeutics Inc 1 AstraZeneca 1 Averitas Pharma, Inc. 1 Baqai Institute of Diabetology and Endocrinology 1 Brigham and Women's Hospital 1 Brown University 1

Trial status mix

COMPLETED31

UNKNOWN12

TERMINATED5

RECRUITING4

WITHDRAWN3

ACTIVE_NOT_RECRUITING2

Phase mix

PHASE227

NA15

PHASE312

PHASE12

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.