Condition

Pleural Effusion

ClinicalTrials.gov condition label

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Search results distinguish clinical terminology from original registry names. Shared trial participation does not imply treatment or approval.

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This is the original ClinicalTrials.gov condition label, found in 27 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials27

Recruiting5

Common interventions25

Lead sponsors shown15

Clinical trials

27 shown

Pleural Effusion Biomarkers in Lung Adenocarcinoma PatientsNCT07012759 · 2025-06-10

ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNGNCT06959719 · 2025-04-14

Strategy for Prompt and Effective Thoracentesis in the Emergency DepartmentNCT06180603 · 2024-01-15

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICUNCT06538376 · 2023-12-12

First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.NCT06946498 · 2023-05-23

AI Assisted Detection of Chest X-RaysNCT06075836 · 2023-10-31

Enhancing Respiratory Auscultation Skills Among Medical Students: Digital Stethoscopes in Medical EducationNCT06359158 · 2023-08-01

Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)NCT05797649 · 2023-07-01

Retrospective Study of Carebot AI CXR Performance in Preclinical PracticeNCT05594485 · 2022-08-15

Local Anesthesia Versus Combined Local Anesthesia With Single Dose Analgesia on Pain Control During Thoracic Ultrasound Guided ProceduresNCT05121233 · 2021-11-01

Thoracentesis to Alleviate Cardiac Pleural EffusionNCT05017753 · 2021-08-31

Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural InterventionNCT05910112 · 2020-09-01

Value of Additional Upfront Systematic Lung Ultrasound in the Workup of Patients With Unilateral Pleural EffusionNCT04235998 · 2020-02-17

Evaluation of Ultra-portable Ultrasound in General PracticeNCT04127149 · 2019-12-03

The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.NCT03678090 · 2018-12-01

Betadine Pleurodesis Via Tunneled Pleural CathetersNCT02975921 · 2018-07-01

Minirigid Versus Conventional Rigid Thoracoscopy in Undiagnosed Pleural EffusionsNCT03449602 · 2018-03-01

Novel Pleural Fluid, Biopsy and Serum Biomarkers for the Investigation of Pleural EffusionsNCT03661801 · 2017-10-26

Noninvasive Ventilation Therapy for the Treatment of Pleural Effusion in Patients With Heart FailureNCT03189654 · 2017-07-01

Data Visualization of Kidney and Prostate Tumors Using Routine Pre-Operative Imaging, 3D Printed, and 3D Virtual Reality ModelsNCT03656822 · 2017-02-07

Evaluation of Implementation of a National Point-of-Care Ultrasound Training ProgramNCT03296280 · 2016-10-03

International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)NCT03210298 · 2016-01-01

Driving Pressure And EFL in Adult Cardiac SurgeryNCT03064659 · 2015-11-01

The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung ResectionNCT01612975 · 2014-04-01

Comparison of Pleural Drainage Systems on Reducing Pleural Effusion Formation Following Lung ResectionNCT01776372 · 2013-01-01

Echocardiographic Examination Performed by Nurses in Cardiac Intensive Care UnitNCT00886548 · 2009-04-01

Malignant Pleural Effusion With ZD6474NCT00402896 · 2006-10-01

Common interventions

PlaceboDRUG2 Air Entrainment - intentional introduction of the atmospheric air into the pleural space.PROCEDURE1 Atrium Express Dry Seal Chest DrainDEVICE1 biomarkersOTHER1 Carebot AI CXRDEVICE1 Cases readingOTHER1 Conventional rigid thoraoscopyDEVICE1 DiclofenacDRUG1 Digital stethoscope useDEVICE1 Gravity fluid drainage in the radiology departmentPROCEDURE1 Ground truthingOTHER1 Local Anesthesia ThoracoscopyPROCEDURE1 Manual drainage in the emergency departmentPROCEDURE1 Medela Thopaz Thoracic Drainage SystemDEVICE1 Mini-thoracoscopyDEVICE1 NaproxenDRUG1 Non-invasive ventilationDEVICE1 PIPACCOMBINATION_PRODUCT1 Pleural interventionsPROCEDURE1 Pleuroscopy with Rigid Thoracoscope and Forceps biopsiesDEVICE1 Portable Dynamic Digital Radiography (DDR)DIAGNOSTIC_TEST1 Povidone-IodineDRUG1 Routine CTDIAGNOSTIC_TEST1 Routine imaging CT with a 3D printed modelDIAGNOSTIC_TEST1 Routine imaging CT with a VR modelDIAGNOSTIC_TEST1

Mapped drugs appearing in these trials

Shared trial participation only; not evidence of efficacy or approval.

placebo2 diclofenac1 naproxen1 povidone-iodine1

Leading sponsors

McMaster University 2 University of Oxford 2 Yale University 2 Assiut University 1 Bispebjerg Hospital 1 Brigham and Women's Hospital 1 Cambridge University Hospitals NHS Foundation Trust 1 Carebot s.r.o. 1 Chinese University of Hong Kong 1 Chung Shan Medical University 1 Fu Jen Catholic University 1 Heart and Diabetes Center North-Rhine Westfalia 1 Helse Nord-Trøndelag HF 1 Hospices Civils de Lyon 1 M.D. Anderson Cancer Center 1

Trial status mix

COMPLETED13

RECRUITING5

UNKNOWN4

WITHDRAWN3

TERMINATED2

Phase mix

NA9

PHASE23

PHASE42

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.