Condition
Primary Open-angle Glaucoma
ClinicalTrials.gov condition label
How to interpret these research links
Connected source recordsThis is the original ClinicalTrials.gov condition label, found in 44 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.
Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.
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Clinical trials
44 shownAssessment of Endothelial Glycocalyx in Patients With Primary Open-angle GlaucomaNCT05264818 · 2022-05-06
RECRUITINGRetinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot StudyNCT03921931 · 2018-11-26
RECRUITINGEffects of Primary Open-angle Glaucoma on Visual-motor CoordinationNCT06692205 · 2024-11-21
UNKNOWNSafety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle GlaucomaNCT06321562 · 2023-03-01
TERMINATEDMINIject Implantation Combined With Cataract Surgery in Patients With POAG and CataractNCT05432245 · 2023-01-18
ENROLLING_BY_INVITATIONGORE Glaucoma Drainage Implant Clinical Study Dominican RepublicNCT05557058 · 2022-09-14
ACTIVE_NOT_RECRUITINGEffect of Acupuncture on Visual Acuity and Visual Field in Patients With Primary Open-angle GlaucomaNCT05247762 · 2022-02-28
COMPLETEDStudy in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag IsopropylNCT05279716 · 2022-02-15
UNKNOWNSwitching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSDNCT04891588 · 2021-03-08
UNKNOWNBREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular HypertensionNCT03235232 · 2021-02-01
COMPLETEDPrevalence of Ocular Surface Disease in Malaysian Glaucoma PatientsNCT04609345 · 2020-11-01
UNKNOWNSafety and Effectiveness of VISULAS Green Selective Laser Trabeculoplasty (SLT)NCT04519814 · 2020-06-30
COMPLETEDPRESERFLO® MicroShunt Extension StudyNCT04333433 · 2020-05-22
COMPLETEDSIGHT Study: Cost-effectiveness of InnFocus Microshunt Implantation vs. Trabeculectomy.NCT03931564 · 2020-02-01
UNKNOWNDecorin in Sub Scleral TrabeculectomyNCT03924544 · 2019-09-01
UNKNOWNLevobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular HypertensionNCT02617459 · 2019-01-04
COMPLETEDA Clinical Study to Evaluate the Efficacy and Safety of CKD-351NCT03762369 · 2018-12-07
UNKNOWNOptical Coherence Tomography of Nerve Fiber Layer and Ganglion Cell Complex After Cataract ExtractionNCT03889652 · 2018-10-20
COMPLETEDImpact of Glaucoma and Visual Field Loss on Life SpaceNCT03673644 · 2018-10-09
ACTIVE_NOT_RECRUITINGLong-term Safety and Performance of the ARGOS-IO Intraocular Pressure Sensor System in Subjects With Primary Open Angle Glaucoma (POAG)NCT03651336 · 2018-08-15
COMPLETEDModified Trabeculectomy With an ESST Versus Conventional SST for Management of Primary Open Angle GlaucomaNCT03480711 · 2018-07-10
COMPLETEDPRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM)NCT03193333 · 2017-11-06
TERMINATEDEducational Intervention to Adopt SLT as First-Line Glaucoma TreatmentNCT03365778 · 2017-10-23
COMPLETEDPost Approval Study of the CyPass SystemNCT03273907 · 2017-10-12
TERMINATEDPeripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography StudyNCT03323164 · 2017-07-10
COMPLETEDPAIR Study-PAP And IOP Relationship: Study 2NCT03145129 · 2017-03-24
COMPLETEDMetabolomics in Surgical Ophthalmological PatientsNCT03098316 · 2017-01-31
UNKNOWNEfficacy and Tolerability of an Innovative Formulation of BAK-free LatanoprostNCT03331770 · 2017-01-06
COMPLETEDMicropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation GlaucomaNCT03483402 · 2016-12-01
COMPLETEDA Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension PatientsNCT03419975 · 2016-04-26
COMPLETEDIntravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma.NCT02330978 · 2014-01-01
COMPLETEDGlaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery Postmarket RegistryNCT01841437 · 2013-09-01
COMPLETEDCombined Viscocanalostomy, Phacoemulsification, OIogen Implant in Open Angle GlaucomaNCT03782051 · 2013-08-01
COMPLETEDComparison of Vitamin D Status and Vitamin D Receptor Polymorphisms in Patients With High Myopia and Primary Open-angle GlaucomaNCT03021629 · 2013-07-01
COMPLETEDEfficacy and Tolerability of Preservative-free 0.0015% Tafluprost in Glaucoma PatientsNCT03104621 · 2013-03-01
COMPLETEDIOP Fluctuations in Patients With Sleep Apnea With or Without Primary Open Angle Glaucoma Using Positive Airway PressureNCT01560975 · 2012-03-01
COMPLETEDStudy to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular HypertensionNCT01528111 · 2012-03-01
COMPLETEDMulticentric Observational Study on Quality of Life in GlaucomaNCT01742104 · 2012-03-01
COMPLETEDMulticenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract SurgeryNCT01461291 · 2012-01-16
COMPLETEDMulticenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract SurgeryNCT01461278 · 2011-12-22
COMPLETEDStudy of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma PatientsNCT02077231 · 2011-09-01
COMPLETEDSafety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular HypertensionNCT01410188 · 2011-09-01
COMPLETEDAdherence With Fixed Versus Unfixed Glaucoma TherapyNCT01281020 · 2009-05-01
COMPLETEDStudy of Brinzolamide and Timolol When Added to Travoprost in Primary Open-angle Glaucoma or Ocular HypertensionNCT00372827 · 2004-02-01
COMPLETEDCommon interventions
Cataract surgeryPROCEDURE3LatanoprostDRUG3TrabeculectomyPROCEDURE20.0015% tafluprostDRUG1AcupunctureDEVICE1ARGOS-IO Sensor Pressure SystemDEVICE1Benzalkonium chloride (BAK)DRUG1Betaxolol eye dropsDRUG1BREMEN eye dropsDRUG1Brimonidine Ophthalmic SolutionDRUG1Brimonidine TartrateDRUG1Brinzolamide 1% added to Travoprost 0.004%DRUG1carbomer eye gelDRUG1CKD-351DRUG1Combigan®DRUG1combined phacoemulsification and viscocanalostomyPROCEDURE1combined phacoemulsification and viscocanalostomy and ologenPROCEDURE1Continuous Positive Airway PressureDEVICE1Culture and isolation of autologous bone-marrow mesenchymal stem cellsBIOLOGICAL1CyPass Micro-Stent implanted with CyPass 241-S applierDEVICE1D930DRUG1DecorinDRUG1Dorzolamide-Timolol OphthalmicDRUG1Eybelis ophthalmic solution 0.002%DRUG1GlycocheckPROCEDURE1
Leading sponsors
Glaukos Corporation3Alcon Research2Wills Eye2Aristotle University Of Thessaloniki1Cairo University1Carl Zeiss Meditec AG1China Medical University Hospital1Chong Kun Dang Pharmaceutical1EMS1EyeD Pharma1Fondation Ophtalmologique Adolphe de Rothschild1Gangnam Severance Hospital1Implandata Ophthalmic Products GmbH1InnFocus Inc.1iSTAR Medical1
Trial status mix
COMPLETED28
UNKNOWN8
TERMINATED3
ACTIVE_NOT_RECRUITING2
RECRUITING2
ENROLLING_BY_INVITATION1
Phase mix
NA17
PHASE15
PHASE35
PHASE45
PHASE22
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.