Condition

Scleroderma

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 26 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials26

Recruiting6

Common interventions14

Lead sponsors shown15

Clinical trials

26 shown

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.NCT06991114 · 2025-07-09

Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs）NCT06801119 · 2025-03-16

Rheumatology Diet StudyNCT06339957 · 2024-03-01

Rheumatology Patient Registry and BiorepositoryNCT04402086 · 2020-08-04

Maternal Autoimmune Disease Research Alliance (MADRA) RegistryNCT03276923 · 2018-01-01

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordNCT01793168 · 2010-07-01

Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)NCT06843239 · 2025-02-06

ACTIVE_NOT_RECRUITING

Ultrasonic COmparison of Salivary Glands in Autoimmune Diseases (COUGAR)NCT06680310 · 2024-12-01

NOT_YET_RECRUITING

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune DiseaseNCT06587828 · 2023-01-03

COvid-19 Vaccine Booster in Immunocompromised Rheumatic DiseasesNCT05236491 · 2022-03-09

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research InitiativesNCT05635266 · 2021-10-26

Smartphone Mindfulness Meditation for Patients With Rheumatic DiseasesNCT03937856 · 2019-05-07

Cardiac Assessment by PV Loop in IPAH and Scleroderma PAHNCT04610788 · 2019-04-15

CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PHNCT03726398 · 2018-09-01

Endothelial Biomarkers of Systemic Sclerosis-associated Pulmonary HypertensionNCT03459716 · 2018-06-01

Mindfulness Based Stress Reduction in Rheumatic DiseasesNCT03411057 · 2018-01-18

Bosentan Treatment of Digital Ulcers Related to Systemic SclerosisNCT02798055 · 2016-09-30

Pregnancy and Medically Assisted Conception in Rare DiseasesNCT02450396 · 2015-06-01

PatientSpot Formerly Known as ArthritisPowerNCT03840928 · 2015-04-01

Endothelial Microparticles in Systemic Sclerosis Pulmonary HypertensionNCT02331225 · 2014-12-01

Novel Screening Strategies for Scleroderma PAHNCT01959815 · 2013-09-26

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic ConditionsNCT01931644 · 2013-07-01

Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic TreatmentsNCT01642706 · 2012-07-02

Duke Autoimmunity in Pregnancy RegistryNCT00513591 · 2007-08-01

Sleep Disturbances and Pulmonary Artery/Aorta Diameter in Scleroderma PatientNCT00566137 · 2006-02-01

Multi-center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma PatientsNCT00377949 · 2005-02-01

Common interventions

Allogeneic NK CellsDRUG1 Bosentan groupDRUG1 Calm- Mindfulness Meditation smartphone applicationBEHAVIORAL1 Companion blood samples with procedurePROCEDURE1 ControlOTHER1 COVID-19 vaccineBIOLOGICAL1 HN2301 injectionDRUG1 Mindfulness Based Stress Reduction (MBSR)BEHAVIORAL1 No interventionOTHER1 No intervention givenOTHER1 Opsumit 10 Mg TabletDRUG1 PlaceboOTHER1 Specimen sampleDIAGNOSTIC_TEST1 TibulizumabBIOLOGICAL1

Leading sponsors

Johns Hopkins University 3 Duke University 2 Louisiana State University Health Sciences Center in New Orleans 2 Sanguine Biosciences 2 Artiva Biotherapeutics, Inc. 1 Assistance Publique - Hôpitaux de Paris 1 Elpen Pharmaceutical Co. Inc. 1 Franz Rischard, DO 1 Georgetown University 1 Global Healthy Living Foundation 1 Northwell Health 1 Paul R Fortin 1 Sanford Health 1 Shenzhen MagicRNA Biotechnology Co., Ltd 1 TScan Therapeutics, Inc. 1

Trial status mix

COMPLETED9

RECRUITING6

UNKNOWN5

TERMINATED2

WITHDRAWN2

ACTIVE_NOT_RECRUITING1

NOT_YET_RECRUITING1

Phase mix

PHASE24

PHASE32

NA1

PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.