Condition

Substance Abuse

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 71 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials71

Recruiting2

Common interventions25

Lead sponsors shown15

Clinical trials

60 shown

The Trans-Led Care StudyNCT06880705 · 2026-04-14

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant FamiliesNCT06627764 · 2025-06-30

Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral SystemNCT07432555 · 2026-10-20

NOT_YET_RECRUITING

Comparison of the Italian and U.S. Forensic Models for Dual-diagnosis Offenders: a 3-year Longitudinal StudyNCT07585656 · 2026-06-01

NOT_YET_RECRUITING

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose RiskNCT05657106 · 2023-03-06

ACTIVE_NOT_RECRUITING

Electronic SBI(RT) for MSM in ArgentinaNCT05542914 · 2022-11-01

Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved PopulationsNCT05286879 · 2022-03-31

Cost-effectiveness of the Care PathwaysNCT04619836 · 2020-06-26

ENROLLING_BY_INVITATION

To Reach Unrestricted Services for Transgender WomenNCT03877497 · 2019-09-19

Perinatal Mental Health Care in SwitzerlandNCT04185896 · 2019-07-10

Hispanic Men Building Respect Education and Safety/ HoMBRES Manteniendo Respeto, Educacion y Seguridad.NCT03730987 · 2019-04-19

OPTIONS: A Patient-Centered HIV Prevention Decision Aid for PrEP Uptake for Women With Substance Use in Treatment SettingsNCT03651453 · 2018-10-15

Integrated BA and HIV RR Counseling for MSM With Stimulant AbuseNCT03175159 · 2018-03-01

Health and Justice: A Continuum of Care for HIV and SU for Justice-Involved Young Adults (PHASE 2)NCT03369249 · 2017-12-09

Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use DrugsNCT03282890 · 2017-11-20

Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging AdultsNCT03751020 · 2017-10-27

Integrated Care (iCare) at Mount Sinai to Improve Substance Use Diagnosis and Treatment Practices in HIV Clinic SettingsNCT03092596 · 2017-02-02

Victim Impact Modules for Jail InmatesNCT01381146 · 2016-07-15

Implementation Research for Vulnerable Women in South AfricaNCT02733003 · 2015-09-01

Understanding Substance Use and Incident HIV/STI Among Young Black MSMNCT02503618 · 2015-07-01

Yappalli - The Road to Choctaw HealthNCT02400554 · 2015-03-01

Feasibility of Interventions on People Who Inject Drugs in VietnamNCT02573948 · 2014-09-01

Young Women's Health CoOp (Cooperative) in Cape TownNCT02677025 · 2014-05-01

Enhanced Access to HIV Care for Drug Users in San Juan, Puerto RicoNCT01792752 · 2013-12-20

Effect Evaluation of Individual Placement and Support (IPS)NCT01964092 · 2013-05-01

Linking Former Inmates to Primary CareNCT01863290 · 2013-05-01

Goal Setting for Health Behavior and Psychosocial Issues in Primary CareNCT01825746 · 2013-03-01

Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine UsersNCT01614106 · 2013-01-01

Targeting PM to Improve HIV Adherence in Adolescents at Risk for Substance AbuseNCT01959217 · 2012-12-13

Reducing High Risk Behavior in Treatment CourtNCT01481428 · 2012-09-01

Hospital Visit as Opportunity for Prevention and Engagement for HIV-Infected Drug UsersNCT01612169 · 2012-07-01

WHC+ (Women's Health CoOp PLUS)NCT01497405 · 2012-05-01

Substance Treatment and HIV Testing and Referral SystemNCT01488630 · 2011-12-01

A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIVNCT01362634 · 2011-08-01

Seek, Test, and Retain. Linkages for Black HIV+, Substance-Using MSMNCT01790360 · 2011-07-01

Evaluation of Re-Entry Values and Mindfulness Program (REVAMP) With Jail InmatesNCT01378923 · 2011-04-01

Improving Antihypertensive Medication AdherenceNCT01296594 · 2011-02-01

Clinical Intervention Psychosis and AddictionNCT01411566 · 2011-01-01

Adherence to HIV Therapy in Heroin Addicts: Oral vs XR-NTXNCT01101815 · 2010-06-01

Young Women's CoOp StudyNCT01224184 · 2010-05-01

Using Incentives to Improve Parolee Participation and Attendance in Community TreatmentNCT01090245 · 2010-04-01

Stonewall Treatment Evaluation ProjectNCT01129401 · 2010-03-01

Juvenile Offender HIV Prevention and Drug Abuse ServicesNCT01922297 · 2010-01-01

Screening Protocol for Research ParticipantsNCT01010620 · 2009-12-01

Jail-Based Impact of Crime InterventionNCT01378936 · 2009-08-01

Aripiprazole Treatment for Methamphetamine Dependence Among High-risk IndividualsNCT00497055 · 2009-03-01

Health Behaviors in School-age Children: 2009-2010NCT00797095 · 2008-11-19

Risk Reduction for Urban Substance Using Men Who Have Sex With Men (MSM)NCT01327898 · 2008-11-01

Women-Focused HIV Prevention in the Western CapeNCT00729391 · 2008-09-26

Healthy Activities for Prize IncentivesNCT00717444 · 2008-09-01

Transitions: Linkages From Jail To CommunityNCT00841711 · 2008-09-01

Intervention to Reduce Injection Drug UseNCT00786630 · 2007-11-01

Effects of Manualized Treatment in a Seamless SystemNCT01372033 · 2007-06-01

Mirtazapine to Reduce Methamphetamine Use Among MSM With High-risk HIV BehaviorsNCT00497081 · 2007-05-01

Behavior Change and Maintenance Intervention for HIV+ MSM Methamphetamine UsersNCT00432926 · 2007-02-01

Acceptability of Pharmacologic Treatment for Methamphetamine Dependence Among MSMNCT00318409 · 2006-09-01

Evaluation of Treatments for Homeless YouthsNCT01143792 · 2006-09-01

Group Therapy for Women Prisoners With Comorbid Substance Use and DepressionNCT00606996 · 2006-07-01

Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse DisorderNCT00316303 · 2006-02-01

Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use DisorderNCT00130923 · 2005-09-01

Common interventions

PlaceboDRUG3 AripiprazoleDRUG2 Attention ControlBEHAVIORAL2 contingency managementBEHAVIORAL2 Directly Administered Antiretroviral TherapyBEHAVIORAL2 QuetiapineDRUG2 TAUBEHAVIORAL2 Adapted SBIRT-T for transgender womenBEHAVIORAL1 BupropionDRUG1 Case Management + HIV PreventionBEHAVIORAL1 Case management plus facilitated treatment allianceBEHAVIORAL1 CHRP-BBOTHER1 Clozapine versus typical (conventional) and atypical antipsychotic medicationsDRUG1 Cognitive Behavioral TherapyBEHAVIORAL1 Community Reinforcement Approach (CRA) + HIV preventionBEHAVIORAL1 Computer-facilitated HIV interventionBEHAVIORAL1 Contingency management: voucher/monetary incentives for treatment attendanceBEHAVIORAL1 ControlOTHER1 Day Treatment MDFT-HIVOTHER1 Day Treatment SAUOTHER1 Decision aidBEHAVIORAL1 Diabetes Prevention InterventionBEHAVIORAL1 EDGE counseling, no maintenanceBEHAVIORAL1 EDGE counseling, plus maintenanceBEHAVIORAL1 electronic screening and brief intervention.BEHAVIORAL1

Leading sponsors

Yale University8 George Mason University5 Columbia University4 Dartmouth-Hitchcock Medical Center4 RTI International4 San Francisco Department of Public Health3 Creighton University2 Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)2 Nova Southeastern University2 UConn Health2 University of California, Los Angeles2 University of Miami2 University of Pennsylvania2 ANRS, Emerging Infectious Diseases1 April M Young1

Trial status mix

COMPLETED57

UNKNOWN5

NOT_YET_RECRUITING2

RECRUITING2

TERMINATED2

ACTIVE_NOT_RECRUITING1

ENROLLING_BY_INVITATION1

WITHDRAWN1

Phase mix

NA37

PHASE214

PHASE47

PHASE15

PHASE33

EARLY_PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.