Condition

Systemic Sclerosis

ClinicalTrials.gov condition label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov condition label, found in 85 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials85
Recruiting18
Common interventions25
Lead sponsors shown15
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Clinical trials

60 shown
Immun4Cure Cohort of Autoimmune DiseasesNCT07515638 · 2026-06-23
RECRUITING
Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune DiseasesNCT07558850 · 2026-05-10
RECRUITING
Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.NCT06947473 · 2026-03-18
RECRUITING
A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune DiseasesNCT07284797 · 2026-02-24
RECRUITING
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune DiseasesNCT07246096 · 2026-02-20
RECRUITING
A Study of AZD0120 in Autoimmune DiseasesNCT07295847 · 2026-01-09
RECRUITING
EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular DiseasesNCT07077304 · 2025-11-19
RECRUITING
Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune DiseasesNCT07236801 · 2025-11-13
RECRUITING
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAHNCT06947460 · 2025-04-18
RECRUITING
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)NCT06733935 · 2024-11-04
RECRUITING
Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune DiseasesNCT06548607 · 2024-09-14
RECRUITING
Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)NCT06350110 · 2024-07-10
RECRUITING
Search for Diagnostic and Prognostic Biomarkers in Systemic Sclerosis and Inflammatory MyopathiesNCT04917705 · 2021-11-25
RECRUITING
Rheumatology Patient Registry and BiorepositoryNCT04402086 · 2020-08-04
RECRUITING
Deployment o the Multidisciplinary Prospective Cohort ImminentNCT04334031 · 2020-07-20
RECRUITING
Autologous Stem Cell Transplantation in Patients With Systemic SclerosisNCT03630211 · 2018-07-31
RECRUITING
Meir Medical Center Rheumatologic BiobankNCT03473912 · 2018-04-16
RECRUITING
New Orleans Pulmonary Hypertension BiobankNCT03269630 · 2017-12-29
RECRUITING
A Phase 1b Study of C-CAR168 in Participants With Systemic Sclerosis (SSc)NCT07854483 · 2027-03-01
NOT_YET_RECRUITING
A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune DiseasesNCT07782450 · 2026-11-19
NOT_YET_RECRUITING
Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic SclerosisNCT07821398 · 2026-11-01
NOT_YET_RECRUITING
A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the BodyNCT07649265 · 2026-09-15
NOT_YET_RECRUITING
Extracellular Vesicle Dynamics Predicting Vascular Complications and Treatment Response in Systemic SclerosisNCT07717060 · 2026-09-01
NOT_YET_RECRUITING
Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular ResearchNCT07737470 · 2026-09-01
NOT_YET_RECRUITING
CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune DiseasesNCT07596680 · 2026-09-01
NOT_YET_RECRUITING
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard TherapyNCT07676266 · 2026-07-01
NOT_YET_RECRUITING
A Study of CD19 UCAR-T Cells in Subjects With Autoimmune DiseasesNCT07212322 · 2026-01-30
NOT_YET_RECRUITING
Early Clinical Study of UTAA91 Injection for the Treatment of Relapsed/Refractory Autoimmune DiseasesNCT06970951 · 2025-05-18
NOT_YET_RECRUITING
Mesenchymal Stem Cells Infusion in Patients With Autoimmune DiseasesNCT06888973 · 2025-02-01
ENROLLING_BY_INVITATION
Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune DiseasesNCT06549296 · 2024-09-13
SUSPENDED
Integration of Remote Monitoring in the Management of Chronic Immunosuppressive TherapyNCT06544343 · 2024-07-01
UNKNOWN
The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune DiseasesNCT06420154 · 2024-05-27
NOT_YET_RECRUITING
Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune DiseasesNCT06417398 · 2024-05-14
UNKNOWN
An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune DiseaseNCT06379646 · 2024-04-24
UNKNOWN
Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune DiseaseNCT06373081 · 2024-04-20
UNKNOWN
A Study of MK-2225 in Healthy Participants (MK-2225-003)NCT06643390 · 2023-11-21
COMPLETED
A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)NCT05869955 · 2023-09-13
ACTIVE_NOT_RECRUITING
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic DiseasesNCT05879419 · 2023-05-23
ACTIVE_NOT_RECRUITING
Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune DiseasesNCT05859997 · 2023-05-17
ENROLLING_BY_INVITATION
Rheumatology-based Adaptive Intervention for Social Determinants and Health EquityNCT05715463 · 2023-03-01
ACTIVE_NOT_RECRUITING
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of RO7303509 in Participants With Systemic SclerosisNCT05462522 · 2023-01-16
COMPLETED
Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAHNCT05339087 · 2022-10-24
TERMINATED
Occupational and Environmental Causes of Autoimmune DiseasesNCT07000903 · 2022-05-10
COMPLETED
COvid-19 Vaccine Booster in Immunocompromised Rheumatic DiseasesNCT05236491 · 2022-03-09
UNKNOWN
Exercise in People With Systemic SclerosisNCT05234671 · 2021-09-01
COMPLETED
Structural and Functional Impairment of Multiple Organs in Patients With Systemic Sclerosis: A MR Imaging StudyNCT05297474 · 2021-07-01
UNKNOWN
A Study to Investigate Safety of GS-248 and Efficacy on Raynauds' Phenomenon in Systemic SclerosisNCT04744207 · 2020-12-29
COMPLETED
Clinical Risk Assessment of Cognitive Function in Systemic Autoimmune DiseasesNCT06029335 · 2020-09-01
UNKNOWN
Is a History of Pre-eclampsia a Risk Factor for Vascular Phenotype in Women With Systemic Sclerosis?NCT04363021 · 2020-07-06
COMPLETED
Cell Surface Marker Expression in Autoimmune DiseasesNCT03757065 · 2019-06-12
COMPLETED
Objective Measurement Methods for Autoimmune Disease and Dry Eye SyndromeNCT03937271 · 2019-04-01
WITHDRAWN
A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Systemic SclerosisNCT03798366 · 2019-01-14
COMPLETED
A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and DermatomyositisNCT03817424 · 2018-12-13
COMPLETED
Volatile Organic Compounds (VOCs) as a Biomarker in Immune-mediated Pulmonary Arterial Hypertension (PAH)NCT03819777 · 2018-03-01
UNKNOWN
A Systematic Review of Factors Associated With Pulmonary Arterial Hypertension in Systemic SclerosisNCT03889509 · 2018-03-01
COMPLETED
Yellow Fever Vaccine in Patients With Rheumatic DiseasesNCT03430388 · 2018-01-31
COMPLETED
A Study of KHK4827 in Patients With Systemic SclerosisNCT04368403 · 2017-10-06
COMPLETED
Pulmonary Hypertension Screening for Rheumatology Patients (SOPHIE)NCT03446339 · 2017-08-03
UNKNOWN
Echo Systemic SclerosisNCT03143413 · 2017-03-24
UNKNOWN
Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial HypertensionNCT02981082 · 2016-12-01
TERMINATED

Common interventions

Leading sponsors

Trial status mix

COMPLETED28
RECRUITING18
UNKNOWN14
NOT_YET_RECRUITING11
TERMINATED5
ACTIVE_NOT_RECRUITING3
WITHDRAWN3
ENROLLING_BY_INVITATION2
SUSPENDED1

Phase mix

NA19
PHASE119
PHASE214
EARLY_PHASE17
PHASE33
PHASE43
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.