Condition

Valvular Heart Disease

ClinicalTrials.gov condition label

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Search results distinguish clinical terminology from original registry names. Shared trial participation does not imply treatment or approval.

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Connected source records

This is the original ClinicalTrials.gov condition label, found in 26 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials26

Recruiting8

Common interventions25

Lead sponsors shown15

Clinical trials

26 shown

Longitudinal Validation of CIRC TechnologiesNCT07081711 · 2026-05-06

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable MonitorNCT06699056 · 2024-11-21

Efficacy of MitraCLip Vs. PASCAL for the TrEAtment of MitraL REgurgiTation in an All-comer PopulationNCT06634121 · 2024-04-01

European Registry of Transcatheter Repair for Tricuspid RegurgitationNCT06307262 · 2023-10-23

Vibrometer Based Pulse Wave Analysis for Arterial Stiffness and Ischemic Heart Disease Risk AssessmentNCT06984211 · 2023-02-01

Development of CIRC TechnologiesNCT05654272 · 2022-09-09

Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk PatientsNCT04973579 · 2021-05-01

Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of ImagingNCT05081115 · 2021-04-01

a Foundational Model for Cardiovascular Disease Diagnosis and PredictionNCT06591923 · 2024-10-01

Prehabilitation for Patients Undergoing Elective Cardiac SurgeryNCT07704086 · 2024-06-01

Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health ProjectNCT05775354 · 2023-11-01

ENROLLING_BY_INVITATION

Middle East African Registry Women CardioVascular DiseaseNCT05869214 · 2023-05-10

NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR TrialNCT05666713 · 2023-02-21

Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort II: Structural Heart Interventions (PLUTO-II)NCT06204783 · 2022-11-14

Novel Echocardiographic Biomarkers Assessing the Myocardial Work in Heart FailureNCT05573997 · 2022-04-10

Sugammadex Titration in Cardiac Surgery PatientsNCT05246397 · 2022-02-01

In Search of Best Practices for Patients With Heart Failure and Secondary Mitral Regurgitation: An Evaluation of the Inova Heart Failure Treatment AlgorithmNCT06675448 · 2021-01-28

The Relationship Between Inflammatory ARTritis and CArdiac DIseAseNCT05647577 · 2021-01-01

ACTIVE_NOT_RECRUITING

Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging ModalitiesNCT03935178 · 2019-08-05

Validation Study of an Advanced Blood Pressure MonitorNCT04030494 · 2019-03-13

Safety and Efficacy of the Gastric Reactance (XL) in Patients Post-operated of Elective Cardiac SurgeryNCT03799133 · 2018-09-26

Fluid Status and T1-mapping by CMRNCT03372512 · 2018-05-08

Improving Mitral Repair for Functional Mitral RegurgitationNCT03366649 · 2018-03-20

Strategies for Revascularization in Patients Undergoing Heart Valve Surgery With Concomitant Coronary Artery DiseaseNCT02173860 · 2016-07-01

Prognostic Indicators as Provided by the EPIC ClearViewNCT01476995 · 2010-09-01

Sildenafil for Secondary Pulmonary Hypertension Due to Valvular DiseaseNCT00862043 · 2009-04-01

Common interventions

15-minutes of sitting during COR ECG AcquistionDEVICE1 ABCDE-Stress EchoDIAGNOSTIC_TEST1 AF detectionDIAGNOSTIC_TEST1 Angio-guided surgical revascularizationPROCEDURE1 Bioimpedance spectroscopyDIAGNOSTIC_TEST1 BP measurementDIAGNOSTIC_TEST1 Early diagnosis strategyDIAGNOSTIC_TEST1 Educational program and respiration physiotherapyOTHER1 FFR-guided surgical revascularizationPROCEDURE1 Florence deviceDEVICE1 Investigation of clinical profile, laboratory and novel echocardiographic imaging biomarkersDIAGNOSTIC_TEST1 Measuring Right Ventricular Size and FunctionDIAGNOSTIC_TEST1 MitraClipDEVICE1 Moderate MROTHER1 MRIDIAGNOSTIC_TEST1 No InterventionsOTHER1 Papillary Muscle ApproximationPROCEDURE1 Physical exerciseOTHER1 PlaceboDRUG1 Pressure volume (PV) loop measurementOTHER1 SE diastolic assessmentDIAGNOSTIC_TEST1 SE in heart donorsDIAGNOSTIC_TEST1 SE Right ventricular function assessmentDIAGNOSTIC_TEST1 Sildenafil CitrateDRUG1 Simutaneous (single anaesthesia) carotid artery stenting with MicroNet covered stent (CGuard) and cardiac surgery (CABG or surgical valve replacement / repair procedure)PROCEDURE1

Mapped drugs appearing in these trials

Shared trial participation only; not evidence of efficacy or approval.

placebo1 sildenafil citrate1

Leading sponsors

LMU Klinikum 2 The Cleveland Clinic 2 Aristotle University Of Thessaloniki 1 Critical Perfusion Inc. 1 Dartmouth-Hitchcock Medical Center 1 Emory University 1 Epic Research & Diagnostics, Inc. 1 Erasmus Medical Center 1 Fatebenefratelli Hospital 1 HJN Sverige AB/Neko Health 1 Hospital General Universitario Gregorio Marañon 1 Hospital Universitario 12 de Octubre 1 Inova Health Care Services 1 John Paul II Hospital, Krakow 1 Medical University of Vienna 1

Trial status mix

COMPLETED8

RECRUITING8

UNKNOWN6

TERMINATED2

ACTIVE_NOT_RECRUITING1

ENROLLING_BY_INVITATION1

Phase mix

NA8

PHASE42

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.