acanthocephaliasis
MONDO:0000295
An disease or disorder caused by infection with Acanthocephala.
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Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
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Acanthocephaliasis
Acanthocephaliasis is a human disease caused by parasitic worms in the phylum Acanthocephala. They rarely infect humans. The worms' typical definitive hosts are racoons, rats, and swine, but it can survive in humans. Macracanthorhynchus hirudinaceus, Macracanthorhynchus ingens, Moniliformis moniliformis, Acanthocephalus rauschi, Pseudoacanthocephalus bufonis, and Corynosoma strumosum are the species commonly found in humans. It is acquired through consuming raw beetles or cockroaches, including the insect's larvae. The parasite is widely distributed, but cases tend to occur where insects are eaten commonly. Once ingested by a human, the worms will find their way to the intestine and mature. There are severe symptoms due to the mechanical disruption of the lumen. Abdominal pain is common. Acanthocephaliasis can be diagnosed by the presence of eggs in the stool. There is no standardized treatment, but there has been some success with pyrantel pamoate, levamisole, niclosamide, mebendazole, ivermectin, paracetamol, tiabendazole, and piperazine citrate. It is an uncommon condition, and literature on the topic in the field is sparse.
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.