Disease & disorder

amusia

MONDO:0000662

An agnosia that is a loss of the ability to recognize musical notes, rhythms, and intervals.

Clinical trials1
Recruiting0
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Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Amusia

Amusia, also called being tone-deaf, is a musical disorder that appears mainly as a defect in processing pitch but also encompasses musical memory and recognition. Two main classifications of amusia exist: acquired amusia, which occurs as a result of brain damage, and congenital amusia, which results from a music-processing anomaly present since birth. Studies have shown that congenital amusia is a deficit in fine-grained pitch discrimination. Early estimates suggested that 4% of the population has this disorder. More recent direct counts based on a sample of 20,000 people indicate a true rate closer to 1.5%. Acquired amusia may take several forms. Patients with brain damage may experience the loss of ability to produce musical sounds while sparing speech, much like aphasics lose speech selectively but can sometimes still sing. Other forms of amusia may affect specific sub-processes of music processing. Current research has demonstrated dissociations between rhythm, melody, and emotional processing of music. Amusia may include impairment of any combination of these skill sets.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.