Disease & disorder

atypical autism

MONDO:0016052

Atypical autism is a pervasive developmental disorder that does not fit the diagnosis for the other specific autistic spectrum disorders (autism, Asperger syndrome, Rett syndrome or childhood disintegrative disorder) and is characterized by usually milder developmental and social delay and less stereotypical autistic behavior. '

Clinical trials0
Recruiting0
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Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Background context

Pervasive developmental disorder not otherwise specified

Pervasive developmental disorder not otherwise specified (PDD-NOS) is a historic psychiatric diagnosis first defined in 1980 that has since been incorporated into autism spectrum disorder in the DSM-5 (2013). According to the earlier DSM-IV, PDD-NOS referred to "mild or severe pervasive deficits in the development of reciprocal social interaction and/or verbal and nonverbal communication skills, or when stereotyped behavior, interests, and/or activities are present, but the criteria are not met for a specific PDD" or for several other disorders. PDD-NOS was one of four disorders collapsed into the diagnosis of autism spectrum disorder in the DSM-5, and also was one of the five disorders classified as a pervasive developmental disorder (PDD) in the DSM-IV. The ICD-10 equivalents also became part of its definition of autism spectrum disorder, as of the ICD-11. PDD-NOS included atypical autism, a diagnosis defined in the ICD-10 for the case that the criteria for autistic disorder were not met because of late age of onset, or atypical symptomatology, or both of these. Even though PDD-NOS was considered milder than typical autism, this was not always true. While some characteristics may be milder, others may be more severe.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.