autoinflammatory disease, familial, Behcet-like-3
MONDO:0032659
An inborn error of immunity caused by variants in the RELA gene that cause decreased RELA (NF-kB p65) protein function. The disease is characterized by chronic mucocutaneous ulcerations, variable immune deficiency, lymphoproliferation with autoimmune cytopenias, inflammatory bowel disease, and autoinflammatory manifestations such as recurrent fever and arthralgia. Affected Individuals express various combinations of clinical features.
Research intelligence
Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
Medications under investigation
Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
MONDO disease family
Recruiting studies by city
Trial status
Trial phase
Study start year
Investigated drug interventions
Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.