Disease & disorder

body dysmorphic disorder

MONDO:0000690

Preoccupations with appearance or self-image causing significant distress or impairment in important areas of functioning.

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Synonyms1

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Body dysmorphic disorder

Body dysmorphic disorder (BDD), also known in some contexts as dysmorphophobia or simply dysmorphia, is a mental disorder defined by an overwhelming preoccupation with a perceived flaw in one's physical appearance. In BDD's delusional variant, the flaw is imagined. When an actual visible difference exists, its importance is disproportionately magnified in the mind of the individual. Whether the physical issue is real or imagined, ruminations concerning this perceived defect become pervasive and intrusive, consuming substantial mental bandwidth for extended periods each day. This excessive preoccupation induces severe emotional distress and also disrupts daily functioning and activities. The DSM-5 places BDD within the obsessive–compulsive spectrum, distinguishing it from disorders such as anorexia nervosa. BDD is estimated to affect up to 2 to 3% of the population. It usually starts during adolescence, and affects men and women at roughly similar rates. The BDD subtype muscle dysmorphia, perceiving the body as too small, affects mostly men. In addition to thinking about it, the sufferer typically checks and compares the perceived flaw repetitively and can adopt unusual routines to avoid social contact that exposes it. Fearing the stigma of vanity, they usually hide this preoccupation. Commonly overlooked even by psychiatrists, BDD has been underdiagnosed. As the disorder severely impairs quality of life due to educational and occupational dysfunction and social isolation, those experiencing BDD tend to have high rates of suicidal thoughts and may attempt suicide.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.