Brown-Sequard syndrome
MONDO:0003754
Brown-Sequard syndrome is a rare neurological condition that results from an injury or damage to one side of the spinal cord. This condition results in weakness or paralysis on one side of the body (hemiparaplegia) and a loss of sensation on the opposite side (hemianesthesia). Brown-Sequard syndrome most commonly occurs in the the thoracic spine (upper and middle back). There are several causes of Brown-Sequard syndrome, including: a spinal cord tumor, trauma (such as a puncture wound to the neck or back), infectious or inflammatory diseases (tuberculosis or multiple sclerosis), and disk herniation. Treatment for this condition varies depending on the underlying cause.
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Brown-Séquard syndrome
Brown-Séquard syndrome (also known as Brown-Séquard's hemiplegia, Brown-Séquard's paralysis, hemiparaplegic syndrome, hemiplegia et hemiparaplegia spinalis, or spinal hemiparaplegia) is a neurological condition caused by damage to one half of the spinal cord. The condition presents clinically with spastic paralysis and loss of fine touch perception, vibratory sensation and proprioception just below the lesion on the same side of the body as the lesion, but with loss of crude touch, pain and temperature sensation on the opposite side and beginning somewhat lower than the lesion. At the level of the lesion, on the same side of the lesion, there is meanwhile a region of flaccid paralysis and complete loss of all sensation. Because injury to a whole half but only one half of the spinal cord only rarely occurs under real-life circumstances, the condition is most often encountered in partial forms. It is named after physiologist Charles-Édouard Brown-Séquard, who first described the condition in 1850.
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.