Disease & disorder

childhood-onset epilepsy syndrome

MONDO:0020072

A epilepsy syndrome that occurs during childhood.

Clinical trials0
Recruiting0
Drug concepts studied0
Synonyms5

Disease research snapshot

No clinical trials have been linked to this exact normalized concept in the current published dataset. This is a coverage limitation, not evidence that the condition or medicine has never been studied. Try a synonym or browse registry-reported labels.

Numbers are derived from CureCurrent's current ClinicalTrials.gov projection and conservative MONDO/RxNorm mappings. See sources, counting rules and limitations and verify eligibility or clinical findings with the original study record.

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Epilepsy in children

Epilepsy is a neurological condition of recurrent episodes of unprovoked epileptic seizures. A seizure is an abnormal neuronal brain activity that can cause intellectual, emotional, and social consequences. Epilepsy affects children and adults of all ages and races, and is one of the most common neurological disorders of the nervous system. Epilepsy is more common among children than adults, affecting about 6 out of 1000 US children that are between the age of 0 to 5 years old. The epileptic seizures can be of different types depending on the part of the brain that was affected, seizures are classified in 2 main types partial seizure or generalized seizure. Once a child has their first seizure or suspect seizure, they should be referred to specialized paediatrician in epilepsy and seizures to assess the seizure and conclude a diagnosis. The specialist doctor will take a detailed history of the child, perform physical examinations, clinical laboratory tests such as blood and genetic test, and neuroimaging. If the child is suspected of epileptic seizures, then additional investigations are to be performed such as, an electroencephalogram (EEG) which can give more information of the brain electrical activity and the seizure type. The epileptic seizure in the vast majority of pediatric epilepsy patients is ephemeral, and symptoms typically subside on their own after the seizure comes to an end, but some children experience what is known as a "seizure cluster," in which the first seizure is followed by a second episode approximately six hours later. These recurrent seizure ep...

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.