complement component 2 deficiency
MONDO:0009006
Complement component 2 deficiency (C2D) is a genetic condition that affects the immune system. Signs and symptoms include recurrent bacterial infections and risk for a variety of autoimmune conditions. Infections can be very serious and are common in early life. They become less frequent during the teen and adult years. The most frequent autoimmune conditions associated with C2D are lupus (10-20%) and vasculitis. C2D is caused by mutations in the C2 gene and is inherited in an autosomal recessive fashion.
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Complement 2 deficiency
Complement 2 deficiency is a type of complement deficiency caused by any one of several different alterations in the structure of complement component 2. It has been associated with an increase in infections. It can present similarly to systemic lupus erythematosus (SLE).
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.