cystitis
MONDO:0006032
Inflammation of the urinary bladder.
Research intelligence
Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
Medications under investigation
Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
MONDO disease family
Recruiting studies by city
Trial status
Trial phase
Study start year
Investigated drug interventions
Urinary tract infection
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract, which includes the bladder, urethra and the kidney. Lower UTIs affect the bladder (cystitis) or urethra while upper UTIs affect the kidney (pyelonephritis). Symptoms from a lower UTI include burning or pain during urination, pain in the lower abdomen and the urge to urinate even when the bladder is empty. Symptoms of a kidney infection are more systemic and include fever or flank pain, usually in addition to the symptoms of a lower UTI. Rarely, the urine may appear bloody. Symptoms may be less clear in very young or old people. The most common cause of infection is E. coli, though other bacteria or fungi may sometimes be the cause. Risk factors include being female, sexual intercourse, diabetes, using a catheter, and family history. Additional factors that have been found to increase the risk of infection include urinary retention (delaying urination), insufficient water intake, use of spermicides as a contraceptive method, and poor genital hygiene. Kidney infections usually occur when a bladder infection spreads, but may also come from bacteria in the blood. Diagnosis in young healthy women can be based on symptoms alone. In those with vague symptoms, diagnosis can be harder because bacteria may be present even if there is no infection. In uncomplicated cases, UTIs are usually treated with a short course of antibiotics. Resistance to many of the antibiotics used to treat this condition is increasing. In complicated cases, a longer course or intravenous antibiotics may be needed. If...
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.