Disease & disorder

delusional disorder

MONDO:0004359

A disorder characterized by the presence of one or more nonbizarre delusions that persist for at least 1 month; the delusion(s) are not due to schizophrenia or a mood disorder, and do not impair psychosocial functioning apart from the ramifications of the delusion(s).

Clinical trials27
Recruiting4
Drug concepts studied3
Synonyms0

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

Loading mapped interventions…

MONDO disease family

Loading verified ontology relationships…

Recruiting studies by city

Loading research-site locations…

Trial status

Loading…

Trial phase

Loading…

Study start year

Loading…

Investigated drug interventions

Loading…
Background context

Delusional disorder

Delusional disorder is a mental disorder in which a person has delusions, but with no accompanying prominent hallucinations, thought disorder, mood disorder, or significant flattening of affect. Delusions are a specific symptom of psychosis. Delusions can be bizarre or non-bizarre in content; non-bizarre delusions are fixed false beliefs that involve situations that could occur in real life, such as being harmed or poisoned. Apart from their delusion or delusions, people with delusional disorder may continue to socialize and function in a normal manner and their behavior may not necessarily seem odd. However, the preoccupation with delusional ideas can be disruptive to their overall lives. For the diagnosis to be made, auditory and visual hallucinations cannot be prominent, though olfactory or tactile hallucinations related to the content of the delusion may be present. The delusions cannot be due to the effects of a drug, medication, or general medical condition, and delusional disorder cannot be diagnosed in an individual previously properly diagnosed with schizophrenia. A person with delusional disorder may be high-functioning in daily life as measured, for example, by the Global Assessment of Functioning. Recent and comprehensive meta-analyses of scientific studies point to an association with a deterioration in aspects of IQ in psychotic patients, in particular, perceptual reasoning, although the between-group differences were small. According to German psychiatrist Emil Kraepelin, patients with delusional disorder remain coherent, sensible, and reasonable. The Diag...

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

27 shown
Enhancing Veteran-Clinical Collaboration in VA PRRCsNCT06898879 · 2026-08-12
RECRUITING
FEEL-GOOD: A Multicenter Trial of a Mindfulness-Based Group Therapy in Young Adults With Early PsychosisNCT07645443 · 2026-05-27
RECRUITING
The Efficacy of Metacognitive Skills Training in the Context of Forensic Psychiatric CareNCT06005766 · 2023-09-01
RECRUITING
Biomarkers/Biotypes, Course of Early Psychosis and Specialty ServicesNCT06740383 · 2023-01-01
RECRUITING
Shared Decision Making for Antipsychotic MedicationsNCT05416658 · 2027-01-01
NOT_YET_RECRUITING
SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial DisabilitiesNCT06007105 · 2025-09-18
COMPLETED
Young Adults With Violent Behavior During Early Psychosis (Aim 2)NCT05756855 · 2024-03-19
COMPLETED
Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum DisordersNCT06423651 · 2022-09-01
UNKNOWN
Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental IllnessNCT04324944 · 2022-07-05
COMPLETED
Rituximab Treatment for Psychosis And/or Obsessive Compulsive Disorder with Probable Immune System InvolvementNCT04323566 · 2022-05-01
ENROLLING_BY_INVITATION
Feasibility of a Novel Process-based Treatment for Patients With PsychosisNCT04874974 · 2021-05-10
COMPLETED
The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode PsychosisNCT04916626 · 2021-05-06
COMPLETED
Effect of Individual Cognitive Stimulation at Home in Adults With Psychotic DisordersNCT04783285 · 2021-03-29
COMPLETED
Research Into Antipsychotic Discontinuation and Reduction TrialNCT03559426 · 2016-03-24
COMPLETED
D-Cycloserine Augmentation of Cognitive Behavioral Therapy for DelusionsNCT01981759 · 2014-02-01
COMPLETED
Pilot-trial of Emotion-focused Cognitive Behavior Therapy for Patients With SchizophreniaNCT02787122 · 2014-01-01
COMPLETED
Agomelatine Treatment of Depression in Schizophrenia (AGOPSYCH)NCT01822418 · 2013-01-01
COMPLETED
Multi-disciplinary Treatment for Patients Experiencing First Episode of PsychosisNCT01216891 · 2010-10-01
COMPLETED
Minimizing Doses of Antipsychotic Medication in Older Patients With Schizophrenia.NCT00716755 · 2009-10-01
COMPLETED
Acceptance and Commitment Therapy for DelusionsNCT00657631 · 2008-04-01
COMPLETED
Schizophrenic Patients Taking Part in Integrated Care ProgramNCT00617214 · 2008-01-01
TERMINATED
Anticholinergic Burden in SchizophreniaNCT00715377 · 2007-06-01
TERMINATED
Integrated Care in Psychotic Disorders With Severe Mental IllnessNCT01888627 · 2007-05-01
UNKNOWN
Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset PsychosisNCT00465920 · 2007-05-01
UNKNOWN
Trial of Cognitive Behavioral Therapy for SchizophreniaNCT00300651 · 2006-03-01
UNKNOWN
Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes MellitusNCT00222807 · 2003-08-01
COMPLETED
A Study of the Efficacy and Safety of Intramuscular Ziprasidone Followed by Oral Ziprasidone for the Treatment of PsychosisNCT00644800 · 2003-07-01
COMPLETED

Leading sponsors

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.