Disease & disorder

erysipelas

MONDO:0001266

An infection of the upper layers of the skin caused by species of streptococcus. Erysipelas results in a fiery red rash with raised edges that can easily be distinguished from the skin around it. The affected skin may be warm to the touch.

Clinical trials1
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Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Erysipelas

Erysipelas () is a relatively common bacterial infection of the superficial layer of the skin (upper dermis), extending to the superficial lymphatic vessels within the skin, characterized by a raised, well-defined, tender, bright-red rash, typically on the face or legs, but which can occur anywhere on the skin. It is a form of cellulitis and is potentially serious. Erysipelas is usually caused by the bacterium Streptococcus pyogenes, also known as group A, β-hemolytic streptococci, which enters the body through a break in the skin, such as a scratch or an insect bite. It is more superficial than cellulitis and is typically more raised and demarcated. The term comes from the Greek ἐρυσίπελας (erysípelas), meaning red skin. In animals, erysipelas is a disease caused by infection with the bacterium Erysipelothrix rhusiopathiae. In animals, it is called diamond skin disease, and occurs especially in pigs. Heart valves and skin are affected. E. rhusiopathiae can also infect humans, but in that case, the infection is known as erysipeloid and is an occupational skin disease.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.