Disease & disorder

erythrasma

MONDO:0002885

A chronic bacterial infection of major folds of the skin, caused by Corynebacterium minutissimum.

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Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Erythrasma

Erythrasma is a superficial skin infection that causes brown, scaly skin patches. It is caused by the bacteria Corynebacterium minutissimum, which is normally part of skin flora (the microorganisms that are normally present on the skin). There are two types of erythrasma: interdigital and generalized. Interdigital is the most common bacterial infection of the feet and is typically asymptomatic. Generalized erythrasma is most commonly seen in type 2 diabetes mellitus where the lesions go beyond the areas of the body where skin is rubbing together. It is prevalent among diabetics and the obese, and in warm climates; it is worsened by wearing occlusive clothing. The presence of erythrasma is approximately 4% and is more likely to be found in the subtropical and tropical areas compared to the rest of the world. It is found more commonly in African Americans due to the darker skin and even though both sexes are affected, it is usually found more frequently in males for the thigh and leg regions. A great contributor to this infection is a weakened immune system which comes with aging, therefore the elderly are more susceptible to this disease than the young; this does not mean the young cannot be affected. The epidemiology background of erythrasma remains partially unsolved.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.