Disease & disorder

gingivitis

MONDO:0002508

A disorder involving inflammation of the gums; may affect surrounding and supporting structures of the teeth.

Clinical trials14
Recruiting1
Drug concepts studied0
Synonyms5

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Background context

Gingivitis

Gingivitis, also known as ulitis, is a non-destructive disease that causes inflammation of the gums. The most common form of gingivitis, and the most common form of periodontal disease, is in response to bacterial biofilms (also called plaque) that are attached to tooth surfaces, termed plaque-induced gingivitis. Most forms of gingivitis are plaque-induced. Although gingivitis does not always progress to periodontitis, periodontitis is always preceded by gingivitis. Gingivitis is reversible with good oral hygiene; however, without treatment, gingivitis can progress to periodontitis, in which the inflammation of the gums results in tissue destruction and bone resorption around the teeth. Periodontitis can ultimately lead to tooth loss.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

14 shown
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose ControlNCT06890676 · 2024-03-01
RECRUITING
Effects of Nonsurgical Periodontal Treatment on GCF Calprotectin and IL-10 in Rheumatoid ArthritisNCT07844564 · 2025-07-17
COMPLETED
Salivary and Serum Inflammatory Biomarkers in Diabetic Nephropathy by Periodontal StatusNCT07498894 · 2024-06-10
COMPLETED
Periodontal Management in Hypertensive Patients (PERIOTENSION Trial I)NCT04328389 · 2024-06-01
UNKNOWN
Gingival Health and Malocclusion Among Type 1 Diabetic Children and AdolescentsNCT06291129 · 2022-10-30
UNKNOWN
Asprosin, Adropin, Irisin Levels in PeriodontitisNCT06250764 · 2020-02-12
COMPLETED
Diet, Diabetes and PeriodontitisNCT03407508 · 2018-10-17
UNKNOWN
Dental Prophylaxis and Rheumatoid ArthritisNCT03087240 · 2017-02-28
UNKNOWN
Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-studyNCT05146557 · 2015-07-01
COMPLETED
Iranian Traditional Mouth Rinse Punica Granatum Pleniflora (Golnaar) in Treatment of Gingivitis in Diabetic PatientsNCT02227485 · 2014-07-01
COMPLETED
Assessment of Periodontal Therapy and Biofilm Management in Breast CancerNCT06212908 · 2012-09-18
COMPLETED
Obesity and Oxidative Stress in Patients With Different Periodontal StatusNCT02508987 · 2012-09-01
COMPLETED
Mechanical-chemical Gingival Therapy in Diabetics and/or ObeseNCT02123563 · 2012-06-01
COMPLETED
Study on Periodontal Treatment in Diabetic PatientsNCT01271231 · 2010-04-01
COMPLETED

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.