Disease & disorder

hyperphosphatemia

MONDO:0000328

Abnormally high level of phosphate in the blood.

Clinical trials2
Recruiting1
Drug concepts studied1
Synonyms2

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Hyperphosphatemia

Hyperphosphatemia is an electrolyte disorder in which there is an elevated level of phosphate in the blood. Most people have no symptoms while others develop calcium deposits in the soft tissue. The disorder is often accompanied by low calcium blood levels, which can result in muscle spasms. Causes include kidney failure, pseudohypoparathyroidism, hypoparathyroidism, diabetic ketoacidosis, tumor lysis syndrome, and rhabdomyolysis. Diagnosis is generally based on a blood phosphate level exceeding 1.46 mmol/L (4.5 mg/dL). Levels may appear falsely elevated with high blood lipid levels, high blood protein levels, or high blood bilirubin levels. Treatment may include a phosphate low diet and antacids like calcium carbonate that bind phosphate. Occasionally, intravenous normal saline or kidney dialysis may be used. How commonly it occurs is unclear.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.