Disease & disorder

hypoglycemia

MONDO:0004946

Abnormally low level of glucose in the blood.

Clinical trials187
Recruiting13
Drug concepts studied20
Synonyms3

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

Loading mapped interventions…

MONDO disease family

Loading verified ontology relationships…

Recruiting studies by city

Loading research-site locations…

Trial status

Loading…

Trial phase

Loading…

Study start year

Loading…

Investigated drug interventions

Loading…
Background context

Hypoglycemia

Hypoglycemia (American English), also spelled hypoglycaemia or hypoglycæmia (British English), sometimes called low blood sugar, is a fall in blood sugar to levels below normal, typically below 70 mg/dL (3.9 mmol/L). Whipple's triad is used to properly identify hypoglycemic episodes. It is defined as blood glucose below 70 mg/dL (3.9 mmol/L), symptoms associated with hypoglycemia, and resolution of symptoms when blood sugar returns to normal. Hypoglycemia may result in headache, tiredness, clumsiness, trouble talking, confusion, fast heart rate, sweating, shakiness, nervousness, hunger, loss of consciousness, seizures, or death. Symptoms typically come on quickly. Symptoms can persist after blood-glucose levels are restored to normal. The most common cause of hypoglycemia is medications used to treat diabetes such as insulin, sulfonylureas, and biguanides. Risk is greater in people with diabetes who have eaten less than usual, recently exercised, or consumed alcohol. Other causes of hypoglycemia include severe illness, sepsis, kidney failure, liver disease, hormone deficiency, tumors such as insulinomas or non-B cell tumors, inborn errors of metabolism, and several medications. Low blood sugar may occur in otherwise healthy newborns who have not eaten for a few hours. Hypoglycemia is treated by eating a sugary food or drink, for example glucose tablets or gel, apple juice, soft drinks, or lollipops. The person must be conscious and able to swallow. The goal is to consume 10–20 grams of a carbohydrate to raise blood glucose levels to a minimum of 70 mg/dL (3.9 mmol/L). If...

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

40 shown
Enhancing Shared Decision-making to Guide Care for People With Dementia and DiabetesNCT05643144 · 2026-09-29
RECRUITING
FEAR of HYPOGLYCEMIA in PATIENTS WITH DIABETESNCT07329985 · 2026-04-15
RECRUITING
Monitoring Exhaled Breath to Noninvasively Detect Glycemic EventsNCT06893341 · 2025-10-23
RECRUITING
"Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring"NCT07286500 · 2025-07-30
RECRUITING
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes MellitusNCT06575426 · 2025-06-10
RECRUITING
Effect of C-peptide on Hypoglycemic CounterregulationNCT06470295 · 2024-06-01
RECRUITING
Safer Aging With Diabetes MonitoringNCT06296485 · 2024-05-01
RECRUITING
Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 DiabetesNCT06297980 · 2024-03-24
RECRUITING
Continuous Subcutaneous Glucose Monitoring in Critical PatientsNCT06234787 · 2023-11-30
RECRUITING
A Study of Glycemic Control in Left Ventricular AssistNCT05933161 · 2023-11-10
RECRUITING
Diabetes Clinical Decision SupportNCT05447806 · 2022-07-15
RECRUITING
DiGESTnewborn StudyNCT04192422 · 2020-09-01
RECRUITING
French National Cohort of People With Type 1 DiabetesNCT04657783 · 2020-06-10
RECRUITING
Perioperative Hypoglycemia in Diabetic Patients Undergoing Vitrectomy: a Masked CGM Prospective Observational StudyNCT07696910 · 2026-07-15
NOT_YET_RECRUITING
CGM/Clarity Use, Glycemic Control and Clinical OutcomesNCT03827434 · 2024-11-22
WITHDRAWN
Diabetes Islet Preservation Immune TreatmentNCT02586831 · 2024-06-01
WITHDRAWN
Study of a Primary Care Hypoglycemia Prevention ProgramNCT06353217 · 2024-05-22
COMPLETED
Hypoglycemia Biomarkers to Predict Timing of a Hypoglycemic EventNCT06652867 · 2024-03-03
COMPLETED
Concordance of Hypoglycemia Measurement With Simultaneous Use of Two Devices for Continuous Glucose Measurement.NCT06246578 · 2024-01-19
SUSPENDED
Role of Adrenaline in in the Inflammatory Response in DiabetesNCT05990933 · 2023-12-03
COMPLETED
Pilot Feasibility Study for HypoPals, a Mobile Health Program for Improving Hypoglycemia Management.NCT05916131 · 2023-09-19
COMPLETED
Nurse Coaching the Effect of on Glycemic Control, Fear of Hypoglycemia and Risk Perception in Adults With Type 1 Diabetes.NCT05870280 · 2023-08-30
UNKNOWN
Effects of a Health Intervention on Hypoglycemic Coping : a Pilot StudyNCT06384118 · 2023-08-01
COMPLETED
Slow Digestible Carbohydrates and Exercise in Adolescents With Type 1 DiabetesNCT05540132 · 2023-07-15
WITHDRAWN
A Study to Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1DNCT05378672 · 2023-05-09
COMPLETED
Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 DiabetesNCT05616273 · 2023-05-03
COMPLETED
Micro Glucagon During Exercise in Type 1 DiabetesNCT04192019 · 2023-04-01
WITHDRAWN
Continuous Glucose Monitoring for Hyperglycemia in Critically Ill PatientsNCT05442853 · 2023-04-01
COMPLETED
Investigating the Relationship Between Nocturnal Glucose Levels and Motion During SleepNCT05609175 · 2023-02-14
COMPLETED
Remote Glucose Monitoring in Hospital SettingsNCT04797208 · 2023-01-09
UNKNOWN
Galactose - the Ideal Carbohydrate Supplement for Exercise in Type 1 DiabetesNCT05557227 · 2022-12-15
COMPLETED
Neuronostatin - a Glucagonotropic Agent in Humans?NCT06143267 · 2022-12-06
COMPLETED
The HypoVoice StudyNCT05569876 · 2022-11-11
COMPLETED
Glucagon and Advanced HCL System to Prevent Exercise-Induced Hypoglycaemia in People With Type 1 DiabetesNCT05379686 · 2022-09-21
COMPLETED
The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic SubjectsNCT05597605 · 2022-09-21
COMPLETED
FreeStyle Libre 2 Discharge TrialNCT05822232 · 2022-08-17
UNKNOWN
The Effect of Glucose-dependent Insulinotropic Polypeptide on the Alpha Cell Response to Hypoglycaemia in Patients with Type 1 DiabetesNCT06137586 · 2022-08-10
COMPLETED
Acute Changes in Plasma Glucose and Cardiovascular Disease in DiabetesNCT05500352 · 2022-07-01
UNKNOWN
Continuous Glucose Monitoring (CGM) in Long Term Care (LTC) FacilitiesNCT05711108 · 2022-01-19
COMPLETED
Low-dose Glucagon for Prevention of Exercise-Induced Hypoglycemia in People With Type 1 DiabetesNCT05076292 · 2021-11-23
COMPLETED

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.