Disease & disorder

infectious disease

MONDO:0005550

A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact.

Clinical trials40
Recruiting2
Drug concepts studied9
Synonyms8

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Recruiting studies by city

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Trial status

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Investigated drug interventions

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Background context

Infection

An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease is an illness resulting from an infection, and some infectious diseases are also communicable (transmissible). Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune systems. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Treatment for infections depends on the type of pathogen involved. Common medications include: Antibiotics for bacterial infections. Antivirals for viral infections. Antifungals for fungal infections. Antiprotozoals for protozoan infections. Antihelminthics for infections caused by parasitic worms. Infectious diseases remain a significant global health concern; communicable, maternal, neonatal, and nutritional diseases together accounted for an estimated 18.6% of global deaths in 2017. The branch of medicine that focuses on infections is referred to as infectious diseases.

Read on Wikipedia ↗ Wikidata Q18123741 ↗
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

40 shown
Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical IllnessNCT07536035 · 2024-09-30
RECRUITING
Prospective Urban Rural Epidemiology StudyNCT03225586 · 2002-01-01
RECRUITING
Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved PopulationsNCT05286879 · 2022-03-31
COMPLETED
Integrating Enhanced HIV PrEP Into a STI Clinic in LilongweNCT05307991 · 2022-03-09
COMPLETED
Dalbavancin Real-life Utilization in Diabetic Patients Suffering From Infections (DALBADIA)NCT04959799 · 2022-01-02
COMPLETED
Data Driven Behavior Intervention and Medical Outcome Evaluation of Patients' Comprehensive MonitoringNCT04966754 · 2021-08-01
UNKNOWN
PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy 2NCT04815876 · 2021-06-24
COMPLETED
PReclude Infection EVEnts With No Prophylaxis Transperineal BiopsyNCT04843566 · 2021-03-22
COMPLETED
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia AreataNCT04239521 · 2020-10-01
COMPLETED
Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19)NCT04427280 · 2020-05-26
COMPLETED
Remote Continues Glucose Monitoring During the COVID-19 Pandemic in Quarantined Hospitalized PatientsNCT04430608 · 2020-05-25
COMPLETED
Why in Hospital After VATS LobectomyNCT04294108 · 2020-04-20
COMPLETED
A Retrospective Cohort Study on the Risk of Serious Infections in Rheumatoid Arthritis Patients Receiving TocilizumabNCT04115423 · 2020-04-01
UNKNOWN
Pediatric Intensive Care and COVID-19NCT04544878 · 2020-03-26
UNKNOWN
Optimal Antibiotics for Operated Diabetic Foot InfectionsNCT04081792 · 2019-09-04
COMPLETED
Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and ComplicationsNCT04081636 · 2019-09-02
COMPLETED
Metabolomics and Wound Healing in DiabetesNCT04475861 · 2018-10-31
WITHDRAWN
Impact of AferBio® on Quality of Life and Chemotherapy Toxicity in Lung Cancer PatientsNCT03469063 · 2018-06-28
UNKNOWN
Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy.NCT03228108 · 2018-04-03
COMPLETED
Feasibility of SBIRT-PNNCT03057119 · 2018-02-12
COMPLETED
Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot UlcersNCT02447172 · 2015-06-01
COMPLETED
Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot UlcersNCT02427802 · 2015-05-01
COMPLETED
Technology That Permits Focal Dose of Antibiotics to be Delivered to Lower Limb(s) of Diabetic PatientsNCT02158442 · 2013-10-01
COMPLETED
A Pilot Study on Raltegravir, Tenofovir and Emtricitabine for Peri-exposure Prophylaxis for HIV InfectionNCT01697046 · 2012-11-01
UNKNOWN
Immune Response of Patients With Chronic, Staphylococcus Aureus-infected WoundsNCT01551667 · 2012-11-01
COMPLETED
Immune Response to HPV Vaccine Among HIV-1-infected Subjects in BrazilNCT02236234 · 2012-01-01
COMPLETED
Insulin Infusion and Infectious Diabetic Foot Ulcers (IIIFU)NCT00700362 · 2011-12-01
WITHDRAWN
Insulin Infusion Diabetes UlcerNCT00700154 · 2011-11-01
TERMINATED
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of CareNCT01431326 · 2011-11-01
COMPLETED
Outcomes of Non-infected Diabetic Foot Ulcers With/Without AntibioticsNCT01418456 · 2011-08-01
UNKNOWN
Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant PatientsNCT01760356 · 2011-05-01
TERMINATED
Vitamin D and Staphylococcus Aureus in the Diabetes StudyNCT01395290 · 2011-04-01
COMPLETED
The All Ireland Infectious Diseases Cohort ProjectNCT06410053 · 2011-03-01
UNKNOWN
Study in COPD (Chronic Obstructive Pulmonary Disease) Subjects to Investigate Safety, Tolerability, and Pharmacokinetics of Ciprofloxacin After Single Dose Inhalations of 50 mg and 75 mg Ciprofloxacin Inhalation PowderNCT01168895 · 2010-07-01
COMPLETED
GRACE: A Study to Compare the Effectiveness, Safety and Tolerability of PREZISTA (Darunavir)/Ritonavir by Gender and Race When Administered With Other Antiretroviral Medications in Human Immunodeficiency Virus (HIV) Positive Women and Men.NCT00381303 · 2006-11-01
COMPLETED
Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell TransplantNCT00324324 · 2006-05-01
TERMINATED
Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell TransplantationNCT00064311 · 2003-06-01
COMPLETED
New Techniques for Using a Saline Wash as a Diagnostic Tool for Pneumocystis PneumoniaNCT00342589 · 1999-09-28
COMPLETED
Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or LymphomaNCT00005590 · 1999-08-01
COMPLETED
Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)NCT03221127 · 1984-03-01
ACTIVE_NOT_RECRUITING

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.